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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 14
1946 53
1947 84
1948 53
1949 46
1950 104
1951 236
1952 349
1953 532
1954 520
1955 644
1956 682
1957 640
1958 722
1959 722
1960 639
1961 652
1962 464
1963 779
1964 1553
1965 1434
1966 1630
1967 1699
1968 2070
1969 1994
1970 1652
1971 1907
1972 2174
1973 2111
1974 2218
1975 2229
1976 2332
1977 2266
1978 2365
1979 2566
1980 2641
1981 2704
1982 2719
1983 2709
1984 2721
1985 2644
1986 2535
1987 2679
1988 2611
1989 2671
1990 2805
1991 2644
1992 2463
1993 2513
1994 2388
1995 2430
1996 2299
1997 2148
1998 1902
1999 1895
2000 1733
2001 1488
2002 1488
2003 1464
2004 1549
2005 1620
2006 1622
2007 1715
2008 1860
2009 1792
2010 1878
2011 2055
2012 2209
2013 2315
2014 2303
2015 2220
2016 2039
2017 1945
2018 1975
2019 825
2020 6
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122,277 results
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Page 1
Immune Responses in the Liver.
Kubes P and Jenne C. Annu Rev Immunol 2018 - Review. PMID 29328785
The liver is a key, frontline immune tissue. Ideally positioned to detect pathogens entering the body via the gut, the liver appears designed to detect, capture, and clear bacteria, viruses, and macromolecules. ...This balance between immunity and tolerance is essential to liver function. Excessive inflammation in the absence of infection leads to sterile liver injury, tissue damage, and remodeling; insufficient immunity allows for chronic infection and cancer. ...
The liver is a key, frontline immune tissue. Ideally positioned to detect pathogens entering the body via the gut, the liver a …
The liver.
Trefts E, et al. Curr Biol 2017. PMID 29112863 Free PMC article.
Introducing concepts critical to liver development, organization, and physiology sets the stage for these functions and serves to orient the reader. It is important to emphasize that insight into hepatic pathologies and potential therapeutic avenues to treat these conditions requires an understanding of the development and physiology of specialized hepatic functions....
Introducing concepts critical to liver development, organization, and physiology sets the stage for these functions and serves …
Normal liver function. A basis for understanding hepatic disease.
Corless JK and Middleton HM. Arch Intern Med 1983 - Review. PMID 6360063
The physiology of the liver involves metabolism, excretion, and body defense. Within the context of metabolism, the liver is the site of a multitude of biochemical reactions essential to the human organism; included are synthesis, degradation, interconversion, storage, and biotransformation. ...Our overview of hepatic physiology highlights some of these facets of normal hepatic anatomy and function of special relevance to the physician confronting liver dysfunction and its varied clinical consequences....
The physiology of the liver involves metabolism, excretion, and body defense. Within the context of metabolism, the liver
Immune and metabolic shifts during neonatal development reprogram liver identity and function.
Nakagaki BN, et al. J Hepatol 2018. PMID 30171870
However, how the liver adapts both the immune system and enzymatic profile to challenges in the postnatal period remains elusive. ...CONCLUSION: In newborns, the immune and metabolic profiles of the liver are dramatically different to those of the adult liver, which can be explained by the differences in the liver cell repertoire and phenotype. ...
However, how the liver adapts both the immune system and enzymatic profile to challenges in the postnatal period remains elusive. ... …
Dietary and metabolic modulators of hepatic immunity
Carambia A and Herkel J. Semin Immunopathol 2018 - Review. PMID 29110070
The liver maintains homoeostatic tolerance to these mostly harmless antigens. However, the liver also functions as a barrier organ to harmful pathogens and is thus permissive to liver inflammation. The regulation of the delicate balance between liver tolerance and liver inflammation is of vital importance for the organism. ...
The liver maintains homoeostatic tolerance to these mostly harmless antigens. However, the liver also functions as a barrier o …
Metabolic zonation of the liver: regulation and implications for liver function.
Gebhardt R. Pharmacol Ther 1992 - Review. PMID 1409850
Liver parenchyma shows a remarkable heterogeneity of the hepatocytes along the porto-central axis with respect to ultrastructure and enzyme activities resulting in different cellular functions within different zones of the liver lobuli. According to the concept of metabolic zonation, the spatial organization of the various metabolic pathways and functions forms the basis for the efficient adaptation of liver metabolism to the different nutritional requirements of the whole organism in different metabolic states. ...
Liver parenchyma shows a remarkable heterogeneity of the hepatocytes along the porto-central axis with respect to ultrastructure and
Modeling liver electrical conductivity during hypertonic injection.
Castellví Q, et al. Int J Numer Method Biomed Eng 2018. PMID 28557354
Metastases in the liver frequently grow as scattered tumor nodules that neither can be removed by surgical resection nor focally ablated. ...Aiming to assess the capability of increasing the global conductivity of the liver by means of hypersaline fluids, here, it is presented a mathematical model that estimates the NaCl distribution within the liver and the resulting conductivity change. ...
Metastases in the liver frequently grow as scattered tumor nodules that neither can be removed by surgical resection nor focally abla …
Effect of ligation on the viscoelastic properties of liver tissues.
Liu D, et al. J Biomech 2018. PMID 29853319
It has been reported that ex vivo viscoelastic properties of liver tissues usually differ from those measured in in vivo state due to the reasons such as the effects of perfusion, temperature, and native pre-stress. ...In this paper, we propose a simple protocol by ligating the liver when performing ex vivo indentation relaxation tests. Our results show that the viscoelastic kernel function, which measures the intrinsic time-dependent mechanical behavior of a viscoelastic material, determined with the present protocol can describe the in vivo viscoelasticity of liver tissues well in comparison with the ex vivo result measured on a liver without ligation and that obtained in vitro. ...
It has been reported that ex vivo viscoelastic properties of liver tissues usually differ from those measured in in vivo state due to …
"Hepatopancreas"?
van Weel PB. Comp Biochem Physiol A Comp Physiol 1974 - Review. PMID 4149001
An Experimental Study to Measure the Mechanical Properties of the Human Liver.
Karimi A and Shojaei A. Dig Dis 2018. PMID 29131053
However, the data on the mechanical properties of the liver capsule is limited to the animal models or confined to the tensile/compressive loading under single direction. Therefore, this study was aimed at experimentally measuring the axial and transversal mechanical properties of the human liver capsule under both the tensile and compressive loadings. ...
However, the data on the mechanical properties of the liver capsule is limited to the animal models or confined to the tensile/compre …
122,277 results
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