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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 1
1966 3
1967 5
1968 4
1969 8
1970 16
1971 6
1972 24
1973 33
1974 18
1975 12
1976 21
1977 13
1978 12
1979 21
1980 30
1981 29
1982 45
1983 33
1984 38
1985 43
1986 49
1987 49
1988 49
1989 66
1990 61
1991 53
1992 50
1993 55
1994 60
1995 60
1996 45
1997 59
1998 43
1999 52
2000 53
2001 55
2002 50
2003 59
2004 52
2005 63
2006 44
2007 38
2008 63
2009 44
2010 54
2011 55
2012 64
2013 53
2014 46
2015 49
2016 37
2017 29
2018 39
2019 8
2020 0
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2,052 results
Results by year
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Page 1
Pathophysiology of primary biliary cholangitis
Gulamhusein AF and Hirschfield GM. Best Pract Res Clin Gastroenterol 2018 - Review. PMID 30343706
In a genetically susceptible host, multi-lineage loss of tolerance to the E2 component of the 2-oxo-dehydrogenase pathway and dysregulated immune pathways directed at biliary epithelial cells leads to cholestasis, progressive biliary fibrosis, and cirrhosis in a subset of patients. ...
In a genetically susceptible host, multi-lineage loss of tolerance to the E2 component of the 2-oxo-dehydrogenase pathway and dysregulated i …
Evolution of our understanding of PBC
Tanaka A, et al. Best Pract Res Clin Gastroenterol 2018 - Review. PMID 30343708
Primary biliary cholangitis associated with drug-induced liver injury and alcoholic liver fibrosis: A case report.
Sun Y, et al. Medicine (Baltimore) 2018. PMID 30213010 Free PMC article.
Obstructive jaundice and space-occupying lesion in the liver were excluded by imaging examinations. Liver biopsy was performed to confirm the reasons for liver injury. ...When other causes of the liver injury cannot be excluded, liver biopsy is suggested. Histopathological change can be used to further clarify the reasons for liver injury and the principal contradiction as well as to guide the theraputic regimen....
Obstructive jaundice and space-occupying lesion in the liver were excluded by imaging examinations. Liver biopsy was performed …
Liver immunology: How to reconcile tolerance with autoimmunity.
Grant CR and Liberal R. Clin Res Hepatol Gastroenterol 2017 - Review. PMID 27526967
There are several examples of liver tolerance: the relative ease by which liver allografts are accepted and the exploitation of the hepatic microenvironment by the malarial parasite and hepatotrophic viruses are notable examples. ...Despite this, there are three liver diseases with likely autoimmune involvement: primary biliary cirrhosis, primary sclerosing cholangitis and autoimmune hepatitis. ...
There are several examples of liver tolerance: the relative ease by which liver allografts are accepted and the exploitation o …
Primary biliary cirrhosis in adults.
Momah N and Lindor KD. Expert Rev Gastroenterol Hepatol 2014 - Review. PMID 24580040
Primary biliary cirrhosis (PBC) is a chronic, autoimmune, cholestatic liver disease. It is characterized by slow destruction of small intrahepatic bile ducts, impaired biliary secretion and stasis of toxic endogenous bile acids within the liver with progression to liver fibrosis and cirrhosis. ...In most cases, diagnosis relies on a positive antimitochondrial antibody in the context of chronic cholestasis, without the need for a liver biopsy. ...
Primary biliary cirrhosis (PBC) is a chronic, autoimmune, cholestatic liver disease. It is characterized by slow destruction o …
Biliary epithelial cells from the liver of patients with primary biliary cirrhosis: isolation, characterization, and short-term culture.
Joplin R, et al. J Pathol 1990. PMID 2266463
Since biliary epithelial cells of the middle-sized interlobular bile ducts are targets for lymphocyte-mediated damage in patients with primary biliary cirrhosis (PBC), we have developed a method for isolating and maintaining these cells in short-term tissue culture. ...By these criteria cells were judged to be identical to biliary epithelial cells from normal liver. The cells could be maintained in short-term tissue culture for up to 4 weeks without loss of biliary epithelial cell markers. ...
Since biliary epithelial cells of the middle-sized interlobular bile ducts are targets for lymphocyte-mediated damage in patients with prima …
Mouse models of primary biliary cirrhosis.
Concepcion AR and Medina JF. Curr Pharm Des 2015 - Review. PMID 25777756
Primary biliary cirrhosis (PBC) is a chronic and progressive cholestatic liver disease of unknown etiopathogenesis that mainly affects middle-aged women. ...
Primary biliary cirrhosis (PBC) is a chronic and progressive cholestatic liver disease of unknown etiopathogenesis that mainly …
The diagnostic accuracy of biomarkers for diagnosis of primary biliary cholangitis (PBC) in anti-mitochondrial antibody (AMA)-negative PBC patients: a review of literature
de Liso F, et al. Clin Chem Lab Med 2017 - Review. PMID 28731850
Primary biliary cholangitis (PBC), also known as primary biliary cirrhosis, is an autoimmune disease of the liver characterized by anti-mitochondrial antibodies (AMA) in 90%-95% of patients. ...
Primary biliary cholangitis (PBC), also known as primary biliary cirrhosis, is an autoimmune disease of the liver characterize …
Primary biliary cirrhosis.
Laurin JM and Lindor KD. Dig Dis 1994 - Review. PMID 7712616
Primary biliary cirrhosis is a chronic, usually progressive, cholestatic liver disease of presumed autoimmune etiology that affects predominantly young and middle-aged women. ...Liver transplantation is recognized as a procedure to extend and improve the quality of life for patients with advanced disease....
Primary biliary cirrhosis is a chronic, usually progressive, cholestatic liver disease of presumed autoimmune etiology that af …
2,052 results
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