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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 1
1948 3
1951 17
1952 31
1953 30
1954 17
1955 23
1956 19
1957 39
1958 46
1959 56
1960 67
1961 74
1962 66
1963 6
1964 8
1965 156
1966 333
1967 422
1968 564
1969 614
1970 638
1971 742
1972 775
1973 801
1974 894
1975 750
1976 705
1977 701
1978 723
1979 742
1980 730
1981 787
1982 789
1983 918
1984 1063
1985 1116
1986 1173
1987 1182
1988 1204
1989 1357
1990 1304
1991 1336
1992 1330
1993 1489
1994 1464
1995 1609
1996 1555
1997 1583
1998 1661
1999 1702
2000 1887
2001 2023
2002 2174
2003 2381
2004 2554
2005 2794
2006 3133
2007 3342
2008 3492
2009 3584
2010 4113
2011 4570
2012 4876
2013 5202
2014 5640
2015 5929
2016 5601
2017 5773
2018 5787
2019 2794
2020 48
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104,833 results
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Page 1
Wilson disease - liver pathology.
Pronicki M. Handb Clin Neurol 2017 - Review. PMID 28433112
The main message concerning liver pathology is that Wilson disease may be microscopically misinterpreted as many other liver diseases, including viral or autoimmune hepatitis, alcoholic/nonalcoholic steatohepatitis, toxic liver injury, cryptogenic cirrhosis, metabolic liver disease, and many others. The possibility of Wilson disease should be considered in all patients, especially young ones presenting unexplained liver diseases with many variable patterns of microscopic liver involvement....
The main message concerning liver pathology is that Wilson disease may be microscopically misinterpreted as many other live
[Autophagy in chronic liver diseases: a friend rather than a foe?].
Gual P, et al. Med Sci (Paris) 2017 - Review. PMID 28367811 French. Free article.
Thus, it has been anticipated that autophagy would play an essential role in the pathogenesis of chronic liver diseases. Alcoholic liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD) are the most prevalent chronic liver diseases in Western countries, sharing common histopathologic features and a common disease progression. In this review, we discuss the role of autophagy at different stages of NAFLD and ALD as well as in liver regeneration and hepatocarcinogenesis....
Thus, it has been anticipated that autophagy would play an essential role in the pathogenesis of chronic liver diseases. Alcoh …
Golgi protein 73 and its diagnostic value in liver diseases.
Xia Y, et al. Cell Prolif 2019 - Review. PMID 30341783
It is primarily expressed in epithelial cells, which has been found upregulated in hepatocytes in patients suffering from both viral and non-viral liver diseases. GP73 has drawn increasing attention for its potential application in the diagnosis of liver diseases such as hepatitis, liver cirrhosis and liver cancer. ...
It is primarily expressed in epithelial cells, which has been found upregulated in hepatocytes in patients suffering from both viral and non …
Histopathology of Alcohol-Related Liver Diseases.
Roth NC and Qin J. Clin Liver Dis 2019 - Review. PMID 30454825
Excessive alcohol consumption can lead to a spectrum of liver histopathology, including steatosis, steatohepatitis, foamy degeneration, fatty liver with cholestasis, and cirrhosis. ...Liver biopsy is not routinely recommended to ascertain a diagnosis of alcohol-related liver disease in patients with an uncertain alcohol history, because the histologic features of alcohol-related liver diseases can be found in other diseases, including nonalcoholic steatohepatitis and drug-induced liver injury....
Excessive alcohol consumption can lead to a spectrum of liver histopathology, including steatosis, steatohepatitis, foamy degeneratio …
The Pathology of Alcoholic Liver Disease.
Alpert L and Hart J. Clin Liver Dis 2016 - Review. PMID 27373610
The term "alcoholic liver disease" encompasses a spectrum of pathologic conditions ranging from isolated steatosis to established cirrhosis. ...This article reviews the characteristic histologic features of the many forms of alcoholic liver disease. Histologic scoring systems are described, and diseases with overlapping morphologic features and comorbid conditions are also discussed....
The term "alcoholic liver disease" encompasses a spectrum of pathologic conditions ranging from isolated steatosis to established cir …
Histopathology, grading and staging of nonalcoholic fatty liver disease.
Kleiner DE. Minerva Gastroenterol Dietol 2018 - Review. PMID 28948754
Nonalcoholic fatty liver disease (NAFLD) is the liver disease associated with obesity, diabetes and the metabolic syndrome. Although steatosis is a key histological feature, liver biopsies of patients with NAFLD can show a wide range of other findings, including portal and lobular inflammation, ballooning and apoptotic hepatocellular injury, Mallory-Denk bodies, megamitochondria and fibrosis. ...
Nonalcoholic fatty liver disease (NAFLD) is the liver disease associated with obesity, diabetes and the metabolic syndrome. Al …
Dichotomous associations of liver pathology with hepatocellular carcinoma morphology in Middle Africa: the situation in Cameroon.
Amougou MA, et al. BMC Res Notes 2018. PMID 29986749 Free PMC article.
The database of the 360 liver biopsies received and associated medical records were reviewed for histological and demographic analysis. ...RESULTS: Malignancies were confirmed in 24.7% (89/360) of liver biopsies. Primary liver tumors consisted in 80 cases of HCC and one case of hepatoblastoma. ...
The database of the 360 liver biopsies received and associated medical records were reviewed for histological and demographic analysi …
Role of Autophagy in Chronic Liver Inflammation and Fibrosis.
Tseng YJ, et al. Curr Protein Pept Sci 2019 - Review. PMID 30843487
Over the years, studies of autophagy demonstrated its complex physiological and pathological roles in the liver. Apart from regulation of normal metabolic functions such as glycogenolysis, glycogenesis, and β-oxidation, autophagy also contributes to the modulation of various liver diseases. In this review, we provide a concise overview of the role of autophagy in regulating hepatic metabolism in healthy conditions and various chronic liver diseases. ...
Over the years, studies of autophagy demonstrated its complex physiological and pathological roles in the liver. Apart from regulatio …
Liver-associated immune abnormalities.
Grunebaum E and Avitzur Y. Autoimmun Rev 2019 - Review. PMID 30408587
In recent years, the cross talk between the liver and the immune system is being uncovered, in part by studying liver involvement in primary immune deficiencies (PID) and in part by investigating the alterations of the immune system following orthotopic liver transplantation (OLT). Here we review some of the reciprocal interactions between the liver and the immune system. Patients with PID, particularly those involving inherited defects in T and B cells or innate immunity are prone to infections and inflammatory responses that often involve the liver. ...
In recent years, the cross talk between the liver and the immune system is being uncovered, in part by studying liver involvem …
The lymphatic vascular system in liver diseases: its role in ascites formation.
Chung C and Iwakiri Y. Clin Mol Hepatol 2013 - Review. PMID 23837133 Free PMC article.
Its failure plays a crucial role in the development and maintenance of various diseases including liver diseases. Lymphangiogenesis (the growth of lymphatic vessels) and changes in the properties of lymphatic vessels are associated with pathogenesis of tumor metastases, ascites formation, liver fibrosis/cirrhosis and portal hypertension. Despite its significant role in liver diseases and its importance as a potential therapeutic target for those diseases, the lymphatic vascular system of the liver is poorly understood. ...
Its failure plays a crucial role in the development and maintenance of various diseases including liver diseases. Lymph …
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