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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 2
1990 9
1991 3
1992 8
1993 15
1994 18
1995 14
1996 15
1997 18
1998 13
1999 11
2000 18
2001 10
2002 15
2003 17
2004 20
2005 24
2006 30
2007 20
2008 32
2009 28
2010 31
2011 35
2012 38
2013 35
2014 36
2015 33
2016 34
2017 28
2018 25
2019 15
2020 0
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595 results
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Page 1
Liver Regeneration: Analysis of the Main Relevant Signaling Molecules.
Tao Y, et al. Mediators Inflamm 2017 - Review. PMID 28947857 Free PMC article.
Liver regeneration is a highly organized tissue regrowth process and is the most important reaction of the liver to injury. The overall process of liver regeneration includes three phases: priming stage, proliferative phase, and termination phase. ...While during the termination stage, hepatocytes will discontinue to proliferate to maintain normal liver mass and function. Except for cytokine- and growth factor-mediated pathways involved in regulating liver regeneration, new substances and technologies emerge to influence the regenerative process. ...
Liver regeneration is a highly organized tissue regrowth process and is the most important reaction of the liver to inj
Liver Regeneration: Different Sub-Populations of Parenchymal Cells at Play Choreographed by an Injury-Specific Microenvironment.
Manco R, et al. Int J Mol Sci 2018 - Review. PMID 30567401 Free PMC article.
Liver regeneration is crucial for the maintenance of liver functional mass during homeostasis and diseases. In a disease context-dependent manner, liver regeneration is contributed to by hepatocytes or progenitor cells. As long as they are replicatively competent, hepatocytes are the main cell type responsible for supporting liver size homeostasisand regeneration. ...
Liver regeneration is crucial for the maintenance of liver functional mass during homeostasis and diseases. In a diseas
Augmenter of liver regeneration: Essential for growth and beyond.
Ibrahim S and Weiss TS. Cytokine Growth Factor Rev 2019 - Review. PMID 30579845 Free article.
Due to the central role of the liver for body homeostasis, intensive research was conducted to identify factors that might contribute to hepatic growth and regeneration. ...Among them, a protein was identified to specifically support liver regeneration and therefore was named ALR (Augmenter of Liver Regeneration). ...
Due to the central role of the liver for body homeostasis, intensive research was conducted to identify factors that might contribute …
Factors Affecting Liver Regeneration in Living Donors After Hepatectomy.
Ibis C, et al. Med Sci Monit 2017. PMID 29249797 Free PMC article.
BACKGROUND The safety of living liver donors is the paramount priority of liver transplantation surgeons. The liver has an effective regeneration capacity. ...The size of the liver remnant or graft has a major effect on regeneration rate. Postoperative biliary leakage did not have any significant effect on liver regeneration. ...
BACKGROUND The safety of living liver donors is the paramount priority of liver transplantation surgeons. The liver has …
Liver dual arterial blood supply maintains liver regeneration: Analysis of signaling pathways in rats.
Qiao JL, et al. Mol Med Rep 2018. PMID 29115531 Free PMC article.
Liver dual arterial blood supply (LDABS) could increase blood supply to the liver and maintain normal liver regeneration in patients with compromised portal vein. ...Liver regeneration was assessed by histological examination, liver function and liver regeneration rate (LRR). Whole‑genome oligo microarray analysis was used to compare gene expression profile between rats receiving PH and rats receiving PH plus LDABS. ...
Liver dual arterial blood supply (LDABS) could increase blood supply to the liver and maintain normal liver regenera
TGF-β signalling and liver disease.
Fabregat I, et al. FEBS J 2016 - Review. PMID 26807763 Free article.
In the case of the liver, TGF-β signalling participates in all stages of disease progression, from initial liver injury through inflammation and fibrosis, to cirrhosis and cancer. TGF-β has cytostatic and apoptotic effects in hepatocytes, promoting liver differentiation during embryogenesis and physiological liver regeneration. ...
In the case of the liver, TGF-β signalling participates in all stages of disease progression, from initial liver injury throug …
Role of microRNA in liver regeneration.
Yi PS, et al. Hepatobiliary Pancreat Dis Int 2016 - Review. PMID 27020629
RESULTS: We grouped studies that involved miRNA and liver regeneration into two groups: miRNAs as promoters and as inhibitors of liver regeneration. ...CONCLUSIONS: Blocking or stimulating the pathways of miRNAs in liver regeneration may be novel therapeutic strategies in future regeneration-related liver managements. ...
RESULTS: We grouped studies that involved miRNA and liver regeneration into two groups: miRNAs as promoters and as inhibitors …
Engineered fibroblast growth factor 19 protects from acetaminophen-induced liver injury and stimulates aged liver regeneration in mice.
Alvarez-Sola G, et al. Cell Death Dis 2017. PMID 28981086 Free PMC article.
The liver displays a remarkable regenerative capacity triggered upon tissue injury or resection. However, liver regeneration can be overwhelmed by excessive parenchymal destruction or diminished by pre-existing conditions hampering repair. ...FGF19/15 is also important for liver regeneration after partial hepatectomy (PH). Therefore recombinant FGF19 would be an ideal molecule to stimulate liver regeneration, but its applicability may be curtailed by its short half-life. ...
The liver displays a remarkable regenerative capacity triggered upon tissue injury or resection. However, liver rege
Endothelial cell-derived angiopoietin-2 controls liver regeneration as a spatiotemporal rheostat.
Hu J, et al. Science 2014. PMID 24458641
Liver regeneration requires spatially and temporally precisely coordinated proliferation of the two major hepatic cell populations, hepatocytes and liver sinusoidal endothelial cells (LSECs), to reconstitute liver structure and function. ...During the later angiogenic phase of liver regeneration, recovery of endothelial Ang2 expression enables regenerative angiogenesis by controlling LSEC vascular endothelial growth factor receptor 2 expression. ...
Liver regeneration requires spatially and temporally precisely coordinated proliferation of the two major hepatic cell populat
YAP Activation Drives Liver Regeneration after Cholestatic Damage Induced by Rbpj Deletion.
Tharehalli U, et al. Int J Mol Sci 2018. PMID 30501048 Free PMC article.
Here we investigated the liver regeneration process in the context of cholestasis induced by disruption of the Notch signalling pathway. ...SOX9 upregulation in cholestatic liver injury in vitro is independent of Notch signalling. We could comprehensively address that in vivo Rbpj depletion is followed by YAP activation, which influences the transdifferentiation of hepatocytes and thereby contributing to liver regeneration....
Here we investigated the liver regeneration process in the context of cholestasis induced by disruption of the Notch signallin …
595 results
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