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1995 1
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Page 1
Colonoscopy: a review of its yield for cancers and adenomas by indication.
Rex DK. Rex DK. Am J Gastroenterol. 1995 Mar;90(3):353-65. Am J Gastroenterol. 1995. PMID: 7872270 Review.
Patients with indications for screening colonoscopy with a relatively high yield of cancer are those with Lynch syndrome (1 per 39 colonoscopies) and males more than 60 yr old (1 per 64 colonoscopies). ...
Patients with indications for screening colonoscopy with a relatively high yield of cancer are those with Lynch syndrome (1 …
Two-stain immunohistochemical screening for Lynch syndrome in colorectal cancer may fail to detect mismatch repair deficiency.
Pearlman R, Markow M, Knight D, Chen W, Arnold CA, Pritchard CC, Hampel H, Frankel WL. Pearlman R, et al. Mod Pathol. 2018 Dec;31(12):1891-1900. doi: 10.1038/s41379-018-0058-y. Epub 2018 Jul 2. Mod Pathol. 2018. PMID: 29967423 Free PMC article.
All remaining cases, except one, had double somatic mutations. The two-stain method fails to detect some patients with Lynch syndrome: (1) significant staining weaker than the control may be incorrectly interpreted as intact MSH6, or (2) Weak or focal/patchy …
All remaining cases, except one, had double somatic mutations. The two-stain method fails to detect some patients with Lynch syndr …
Lynch syndrome screening strategies among newly diagnosed endometrial cancer patients.
Resnick K, Straughn JM Jr, Backes F, Hampel H, Matthews KS, Cohn DE. Resnick K, et al. Obstet Gynecol. 2009 Sep;114(3):530-536. doi: 10.1097/AOG.0b013e3181b11ecc. Obstet Gynecol. 2009. PMID: 19701031
METHODS: A decision analysis compared four strategies to screen women with newly diagnosed endometrial cancer for Lynch syndrome: 1) Amsterdam criteria strategy, where full gene sequencing was performed for women who meet Amsterdam criteria; 2) Sequence-all s …
METHODS: A decision analysis compared four strategies to screen women with newly diagnosed endometrial cancer for Lynch syndrome …
A cohort analysis of men with a family history of BRCA1/2 and Lynch mutations for prostate cancer.
Kerr L, Rewhorn MJ, Longmuir M, Fraser S, Walsh S, Andrew N, Leung HY. Kerr L, et al. BMC Cancer. 2016 Jul 25;16:529. doi: 10.1186/s12885-016-2573-x. BMC Cancer. 2016. PMID: 27456091 Free PMC article.
RESULTS: Overall 1 of 7 (14 %) and 1 of 20 (5 %) men with BRCA1/2 mutations were positive for a diagnosis of prostate cancer. In men with Lynch syndrome, 1 of 4 (25 %) was diagnosed to have prostate cancer. ...
RESULTS: Overall 1 of 7 (14 %) and 1 of 20 (5 %) men with BRCA1/2 mutations were positive for a diagnosis of prostate cancer. In men with …
Cost-effectiveness analysis of prevention strategies for gynecologic cancers in Lynch syndrome.
Kwon JS, Sun CC, Peterson SK, White KG, Daniels MS, Boyd-Rogers SG, Lu KH. Kwon JS, et al. Cancer. 2008 Jul 15;113(2):326-35. doi: 10.1002/cncr.23554. Cancer. 2008. PMID: 18506736 Free article.
METHODS: Five strategies were compared for a hypothetical cohort of women with Lynch syndrome: 1) no prevention ('reference'); 2) prophylactic surgery (hysterectomy and bilateral salpingo-oophorectomy) at age 30 years; 3) prophylactic surgery at age 40 years; …
METHODS: Five strategies were compared for a hypothetical cohort of women with Lynch syndrome: 1) no prevention ('refer …
Interval colon cancer in a Lynch syndrome patient under annual colonoscopic surveillance: a case for advanced imaging techniques?
Oxentenko AS, Smyrk TC. Oxentenko AS, et al. BMC Gastroenterol. 2012 May 24;12:50. doi: 10.1186/1471-230X-12-50. BMC Gastroenterol. 2012. PMID: 22624972 Free PMC article.
CONCLUSION: Our patient illustrates two current concepts about Lynch syndrome: 1) adenomas are the cancer precursor and 2) such adenomas may be "aggressive," in the sense that the adenoma progresses more readily and more rapidly to carcinoma in this setting c …
CONCLUSION: Our patient illustrates two current concepts about Lynch syndrome: 1) adenomas are the cancer precursor and …
Transanal endoscopic microsurgery approach for rectal stump resection as an alternative to transperitoneal stump resection.
Bremers AJ, van Laarhoven KJ, van der Kolk BM, de Wilt JH, van Goor H. Bremers AJ, et al. Br J Surg. 2013 Mar;100(4):568-71. doi: 10.1002/bjs.9005. Epub 2012 Nov 27. Br J Surg. 2013. PMID: 23188592
RESULTS: The study included nine patients with a rectal stump ranging in length from 8 to 20 cm after previous surgery for inflammatory bowel disease (6), Lynch syndrome (1), collagenous colitis (1) or anastomotic leakage (1). ...
RESULTS: The study included nine patients with a rectal stump ranging in length from 8 to 20 cm after previous surgery for inflammatory bowe …