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Year Number of Results
2002 1
2003 1
2007 2
2009 4
2010 14
2011 35
2012 888
2013 2132
2014 2716
2015 2886
2016 2848
2017 2719
2018 2790
2019 1402
2020 36
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16,094 results
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Page 1
The Story of MCF-7 Breast Cancer Cell Line: 40 years of Experience in Research.
Comşa Ş, et al. Anticancer Res 2015 - Review. PMID 26026074
MCF-7 is a commonly used breast cancer cell line, that has been promoted for more than 40 years by multiple research groups but its characteristics have never been gathered in a consistent review article. The current paper provides a broad description of the MCF-7 cell line, including the molecular profile, proliferation, migration, invasion, spheroid formation, its involvement in angiogenesis and lymphangiogenesis and its interaction with the mesenchymal stem cells....
MCF-7 is a commonly used breast cancer cell line, that has been promoted for more than 40 years by multiple research groups bu
Quercetin induces apoptosis and necroptosis in MCF-7 breast cancer cells.
Khorsandi L, et al. Bratisl Lek Listy 2017. PMID 28814095
Que in presence of Nec-1 decreased expression of Bax gene, reduced apoptotic index, increased cell viability and proliferation of MCF-7 cells in comparison to absence of Nec-1. MCF-7 cells showed a significantly increased expression of RIPK1 and RIPK3 in response to Que plus ZVAD in comparison to absence of ZVAD. ...
Que in presence of Nec-1 decreased expression of Bax gene, reduced apoptotic index, increased cell viability and proliferation of MCF
Nucleocytoplasmic distribution of S6K1 depends on the density and motility of MCF-7 cells in vitro.
Kosach V, et al. F1000Res 2018. PMID 30705751 Free PMC article.
In vitro studies of MCF-7 cells demonstrated that the subcellular localization of S6K1 depends on the cell density in the monolayer culture. ...Conclusions: Subcellular localization of S6K1 depends on the density and locomotor activity of the MCF-7 cells....
In vitro studies of MCF-7 cells demonstrated that the subcellular localization of S6K1 depends on the cell density in t …
Electromagnetic Field Could Protect SH-SY5Y Cells Against Cisplatin Cytotoxicity, But Not MCF-7 Cells.
Mahmoudinasab H and Saadat M. DNA Cell Biol 2018. PMID 29446648
The molecular mechanism of CDDP-reduced cytotoxicity in our designed combinations is probably different in MCF-7 and SH-SY5Y cells. CDDP in combination with EMF could protect SH-SY5Y cells from the cytotoxicity, whereas it has no significant change in MCF-7 cells....
The molecular mechanism of CDDP-reduced cytotoxicity in our designed combinations is probably different in MCF-7 and SH-SY5Y …
In silico analysis of the potential mechanism of telocinobufagin on breast cancer MCF-7 cells.
Dang YW, et al. Pathol Res Pract 2018. PMID 29656985
RESULTS: One GEO accession (GSE85871) provided 1251 differentially expressed genes after telocinobufagin treatment on MCF-7 cells. ...This study only presented a comprehensive picture of the role of telocinobufagin in breast cancer MCF-7 cells using big data. ...
RESULTS: One GEO accession (GSE85871) provided 1251 differentially expressed genes after telocinobufagin treatment on MCF-7
The Effect of Melatonin Adsorbed to Polyethylene Glycol Microspheres on the Survival of MCF-7 Cells.
França EL, et al. Neuroimmunomodulation 2016. PMID 26445481
The MCF-7 cells were obtained from the American Type Culture Collection. MCF-7 cells were preincubated for 24 h with or without melatonin (100 ng/ml), PEG microspheres or melatonin adsorbed to PEG microspheres (100 ng/ml). ...The results indicate that melatonin adsorbed to PEG microspheres exerts antitumor effects on human MCF-7 breast cancer cells. ...
The MCF-7 cells were obtained from the American Type Culture Collection. MCF-7 cells were preincub …
Expression of Snail and E-cadherin in Drug-resistant MCF-7/ADM Breast Cancer Cell Strains.
Cai F, et al. J Coll Physicians Surg Pak 2019. PMID 30823950
OBJECTIVE: To investigate the expression of zinc finger transcription factors-Snail and E-cadherin in adriamycin-resistant human breast cancer MCF-7/ADM cells and non-resistant MCF-7 cells. ...Western blot was used to detect the expression levels of proteins of Snail and E-cadherin in normal breast cells, adriamycin-resistant human breast cancer MCF-7/ADM cells and non-resistant MCF-7 cells. ...
OBJECTIVE: To investigate the expression of zinc finger transcription factors-Snail and E-cadherin in adriamycin-resistant human breast canc …
[Effects of 3β-HSD gene silence or overexpression on DEHP induced oxidative damage in MCF-7 cells].
Wang L, et al. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2018. PMID 29996374 Chinese.
Objective: To study the oxidative damage of di- (2-ethylhexyl) phthalate (DEHP) on MCF-7 cells, and to investigate the effects of 3β-hydroxysteroid dehydrogenase (3β-HSD) gene silence or overexpression on DEHP-induced oxidative damage. ...Conclusion: DEHP could cause oxidative damage in MCF-7 cells, induce the changes of related genes and proteins, 3β-HSD plays an antioxidant role in the process of DEHP ox-idative damage....
Objective: To study the oxidative damage of di- (2-ethylhexyl) phthalate (DEHP) on MCF-7 cells, and to investigate the …
Multiparameter Phenotypic Profiling in MCF-7 Cells for Assessing the Toxicity and Estrogenic Activity of Whole Environmental Water.
Wang W, et al. Environ Sci Technol 2018. PMID 30025452
The present study demonstrates the application of image-based multi-parameter phenotypic profiling in MCF-7 cells to assess the overall toxicity and estrogenic activity of whole environmental water. ...In conclusion, the image-based multi-parameters phenotypic analysis with MCF-7 cells provides a rapid and information-rich tool for toxicity evaluation and identification in whole water samples....
The present study demonstrates the application of image-based multi-parameter phenotypic profiling in MCF-7 cells to as …
Label-free detection of hypoxia-induced extracellular vesicle secretion from MCF-7 cells.
Kilic T, et al. Sci Rep 2018. PMID 29925885 Free PMC article.
Here we present a label-free electrochemical sensor to measure the EVs secretion levels of hypoxic and normoxic MCF-7 cells. ...In order to assess the performance of the biosensor, the level of EVs secretion by the human breast cancer MCF-7 cell line was compared with enzyme-linked immunosorbent assays (ELISA) and Nanoparticle Tracking Analysis (NTA). ...
Here we present a label-free electrochemical sensor to measure the EVs secretion levels of hypoxic and normoxic MCF-7 cells
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