Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2013 1
2014 3
2015 9
2016 16
2017 19
2018 21
2019 17
2020 12
2021 23
2022 26
2023 16
2024 5
2025 8
2026 2

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

146 results

Results by year

Filters applied: . Clear all
Quoted phrase not found in phrase index: "Multicenter Randomized Clinical Trial of Endovascular Treatment of Acute Ischemic Stroke in the Netherlands (MR CLEAN) investigators"
Page 1
A randomized trial of intraarterial treatment for acute ischemic stroke.
Berkhemer OA, Fransen PS, Beumer D, van den Berg LA, Lingsma HF, Yoo AJ, Schonewille WJ, Vos JA, Nederkoorn PJ, Wermer MJ, van Walderveen MA, Staals J, Hofmeijer J, van Oostayen JA, Lycklama à Nijeholt GJ, Boiten J, Brouwer PA, Emmer BJ, de Bruijn SF, van Dijk LC, Kappelle LJ, Lo RH, van Dijk EJ, de Vries J, de Kort PL, van Rooij WJ, van den Berg JS, van Hasselt BA, Aerden LA, Dallinga RJ, Visser MC, Bot JC, Vroomen PC, Eshghi O, Schreuder TH, Heijboer RJ, Keizer K, Tielbeek AV, den Hertog HM, Gerrits DG, van den Berg-Vos RM, Karas GB, Steyerberg EW, Flach HZ, Marquering HA, Sprengers ME, Jenniskens SF, Beenen LF, van den Berg R, Koudstaal PJ, van Zwam WH, Roos YB, van der Lugt A, van Oostenbrugge RJ, Majoie CB, Dippel DW; MR CLEAN Investigators. Berkhemer OA, et al. N Engl J Med. 2015 Jan 1;372(1):11-20. doi: 10.1056/NEJMoa1411587. Epub 2014 Dec 17. N Engl J Med. 2015. PMID: 25517348 Free article. Clinical Trial.
BACKGROUND: In patients with acute ischemic stroke caused by a proximal intracranial arterial occlusion, intraarterial treatment is highly effective for emergency revascularization. ...There were no significant differences in mortality or the occurrenc …
BACKGROUND: In patients with acute ischemic stroke caused by a proximal intracranial arterial occlusion, intraarterial …
Endovascular treatment versus no endovascular treatment after 6-24 h in patients with ischaemic stroke and collateral flow on CT angiography (MR CLEAN-LATE) in the Netherlands: a multicentre, open-label, blinded-endpoint, randomised, controlled, phase 3 trial.
Olthuis SGH, Pirson FAV, Pinckaers FME, Hinsenveld WH, Nieboer D, Ceulemans A, Knapen RRMM, Robbe MMQ, Berkhemer OA, van Walderveen MAA, Lycklama À Nijeholt GJ, Uyttenboogaart M, Schonewille WJ, van der Sluijs PM, Wolff L, van Voorst H, Postma AA, Roosendaal SD, van der Hoorn A, Emmer BJ, Krietemeijer MGM, van Doormaal PJ, Roozenbeek B, Goldhoorn RB, Staals J, de Ridder IR, van der Leij C, Coutinho JM, van der Worp HB, Lo RTH, Bokkers RPH, van Dijk EI, Boogaarts HD, Wermer MJH, van Es ACGM, van Tuijl JH, Kortman HGJ, Gons RAR, Yo LSF, Vos JA, de Laat KF, van Dijk LC, van den Wijngaard IR, Hofmeijer J, Martens JM, Brouwers PJAM, Bulut T, Remmers MJM, de Jong TEAM, den Hertog HM, van Hasselt BAAM, Rozeman AD, Elgersma OEH, van der Veen B, Sudiono DR, Lingsma HF, Roos YBWEM, Majoie CBLM, van der Lugt A, Dippel DWJ, van Zwam WH, van Oostenbrugge RJ; MR CLEAN-LATE investigators. Olthuis SGH, et al. Lancet. 2023 Apr 22;401(10385):1371-1380. doi: 10.1016/S0140-6736(23)00575-5. Epub 2023 Mar 29. Lancet. 2023. PMID: 37003289 Clinical Trial.
METHODS: MR CLEAN-LATE was a multicentre, open-label, blinded-endpoint, randomised, controlled, phase 3 trial done in 18 stroke intervention centres in the Netherlands. ...FUNDING: Collaboration for New Treatments of Acute Strok …
METHODS: MR CLEAN-LATE was a multicentre, open-label, blinded-endpoint, randomised, controlled, phase 3 trial done in 18 st …
A Randomized Trial of Intravenous Alteplase before Endovascular Treatment for Stroke.
LeCouffe NE, Kappelhof M, Treurniet KM, Rinkel LA, Bruggeman AE, Berkhemer OA, Wolff L, van Voorst H, Tolhuisen ML, Dippel DWJ, van der Lugt A, van Es ACGM, Boiten J, Lycklama À Nijeholt GJ, Keizer K, Gons RAR, Yo LSF, van Oostenbrugge RJ, van Zwam WH, Roozenbeek B, van der Worp HB, Lo RTH, van den Wijngaard IR, de Ridder IR, Costalat V, Arquizan C, Lemmens R, Demeestere J, Hofmeijer J, Martens JM, Schonewille WJ, Vos JA, Uyttenboogaart M, Bokkers RPH, van Tuijl JH, Kortman H, Schreuder FHBM, Boogaarts HD, de Laat KF, van Dijk LC, den Hertog HM, van Hasselt BAAM, Brouwers PJAM, Bulut T, Remmers MJM, van Norden A, Imani F, Rozeman AD, Elgersma OEH, Desfontaines P, Brisbois D, Samson Y, Clarençon F, Krietemeijer GM, Postma AA, van Doormaal PJ, van den Berg R, van der Hoorn A, Beenen LFM, Nieboer D, Lingsma HF, Emmer BJ, Coutinho JM, Majoie CBLM, Roos YBWEM; MR CLEAN–NO IV Investigators. LeCouffe NE, et al. N Engl J Med. 2021 Nov 11;385(20):1833-1844. doi: 10.1056/NEJMoa2107727. N Engl J Med. 2021. PMID: 34758251 Clinical Trial.
BACKGROUND: The value of administering intravenous alteplase before endovascular treatment (EVT) for acute ischemic stroke has not been studied extensively, particularly in non-Asian populations. ...(Funded by the Collaboration for New Treatm …
BACKGROUND: The value of administering intravenous alteplase before endovascular treatment (EVT) for acute ischemic …
CT Perfusion Imaging After Selection for Late-Window Endovascular Stroke Treatment: Secondary Analysis of the MR CLEAN-LATE Randomized Trial.
Olthuis SGH, Pinckaers FME, Robbe MMQ, de Ridder IR, Hoving JW, Venema E, Daems JD, Pirson FAVA, Staals J, Emmer BJ, Lingsma HF, Roosendaal SD, van der Hoorn A, Koopman MS, Postma AA, Dippel DWJ, Majoie CB, van Oostenbrugge RJ, van Zwam WH; MR CLEAN-LATE (Multicenter Randomized Clinical Trial of Endovascular Treatment of Acute Ischemic Stroke in the Netherlands for Late Arrivals) Investigators. Olthuis SGH, et al. JAMA Neurol. 2025 Jun 1;82(6):589-596. doi: 10.1001/jamaneurol.2025.0716. JAMA Neurol. 2025. PMID: 40323620 Free PMC article. Clinical Trial.
IMPORTANCE: MR CLEAN-LATE (Multicenter Randomized Clinical Trial of Endovascular Treatment of Acute Ischemic Stroke in the Netherlands for Late Arrivals) showed efficacy of endovascular …
IMPORTANCE: MR CLEAN-LATE (Multicenter Randomized Clinical Trial of Endovascular Treatme …
Endovascular Treatment for Acute Ischemic Stroke in Children: Experience From the MR CLEAN Registry.
van Es ACGM, Hunfeld MAW, van den Wijngaard I, Kraemer U, Engelen M, van Hasselt BAAM, Fransen PSS, Dippel DWJ, Majoie CBLM, van der Lugt A, Emmer BJ; MR CLEAN Registry Investigators. van Es ACGM, et al. Stroke. 2021 Mar;52(3):781-788. doi: 10.1161/STROKEAHA.120.030210. Epub 2021 Feb 22. Stroke. 2021. PMID: 33617341 Free article.
BACKGROUND AND PURPOSE: Multiple trials have shown the efficacy and safety of endovascular therapy (EVT) of acute ischemic stroke in adults. Trials in children are lacking and only case reports and case series exist. However, the long-term outco …
BACKGROUND AND PURPOSE: Multiple trials have shown the efficacy and safety of endovascular therapy (EVT) of acute is …
Endovascular treatment in older adults with acute ischemic stroke in the MR CLEAN Registry.
Groot AE, Treurniet KM, Jansen IGH, Lingsma HF, Hinsenveld W, van de Graaf RA, Roozenbeek B, Willems HC, Schonewille WJ, Marquering HA, van den Berg R, Dippel DWJ, Majoie CBLM, Roos YBWEM, Coutinho JM; MR CLEAN Registry Investigators. Groot AE, et al. Neurology. 2020 Jul 14;95(2):e131-e139. doi: 10.1212/WNL.0000000000009764. Epub 2020 Jun 11. Neurology. 2020. PMID: 32527972 Clinical Trial.
OBJECTIVE: To explore clinical outcomes in older adults with acute ischemic stroke treated with endovascular thrombectomy (EVT). METHODS: We included consecutive patients (2014-2016) with an anterior circulation occlusion undergoing EVT from the Mul …
OBJECTIVE: To explore clinical outcomes in older adults with acute ischemic stroke treated with endovascular thr …
MR CLEAN-LATE, a multicenter randomized clinical trial of endovascular treatment of acute ischemic stroke in The Netherlands for late arrivals: study protocol for a randomized controlled trial.
Pirson FAVA, Hinsenveld WH, Goldhoorn RB, Staals J, de Ridder IR, van Zwam WH, van Walderveen MAA, Lycklama À Nijeholt GJ, Uyttenboogaart M, Schonewille WJ, van der Lugt A, Dippel DWJ, Roos YBWEM, Majoie CBLM, van Oostenbrugge RJ; MR CLEAN-LATE investigators. Pirson FAVA, et al. Trials. 2021 Feb 24;22(1):160. doi: 10.1186/s13063-021-05092-0. Trials. 2021. PMID: 33627168 Free PMC article.
BACKGROUND: Endovascular therapy (EVT) for acute ischemic stroke due to proximal occlusion of the anterior intracranial circulation, started within 6 h from symptom onset, has been proven safe and effective. ...We will investigate the efficacy o …
BACKGROUND: Endovascular therapy (EVT) for acute ischemic stroke due to proximal occlusion of the anterio …
Development and Validation of a Postprocedural Model to Predict Outcome After Endovascular Treatment for Ischemic Stroke.
Chalos V, Venema E, Mulder MJHL, Roozenbeek B, Steyerberg EW, Wermer MJH, Lycklama À Nijeholt GJ, van der Worp HB, Goyal M, Campbell BCV, Muir KW, Guillemin F, Bracard S, White P, Dávalos A, Jovin TG, Hill MD, Mitchell PJ, Demchuk AM, Saver JL, van der Lugt A, Brown S, Dippel DWJ, Lingsma HF; HERMES CollaboratorsMR CLEAN Registry Investigators. Chalos V, et al. JAMA Neurol. 2023 Jul 31;80(9):940-8. doi: 10.1001/jamaneurol.2023.2392. Online ahead of print. JAMA Neurol. 2023. PMID: 37523199 Free PMC article.
IMPORTANCE: Outcome prediction after endovascular treatment (EVT) for ischemic stroke is important to patients, family members, and physicians. ...The model was developed within the Highly Effective Reperfusion Evaluated in Multiple Endovascular …
IMPORTANCE: Outcome prediction after endovascular treatment (EVT) for ischemic stroke is important to patients, …
Association of hyperglycemia and computed tomographic perfusion deficits in patients who underwent endovascular treatment for acute ischemic stroke caused by a proximal intracranial occlusion: A subgroup analysis of a randomized phase 3 trial (MR CLEAN).
Kersten CJBA, Zandbergen AAM, Berkhemer OA, Borst J, Haalboom M, Roos YBWEM, Dippel DWJ, van Oostenbrugge RJ, van der Lugt A, van Zwam WH, Majoie CB, den Hertog HM; MR CLEAN investigators. Kersten CJBA, et al. J Neurol Sci. 2022 Sep 15;440:120333. doi: 10.1016/j.jns.2022.120333. Epub 2022 Jun 30. J Neurol Sci. 2022. PMID: 35834861 Clinical Trial.
METHODS: We used data from the MR CLEAN study (Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands). ...CONCLUSION: Hyperglycemia on …
METHODS: We used data from the MR CLEAN study (Multicenter Randomized Clinical Trial of Endovas …
Endovascular therapy for ischemic stroke.
Berkhemer OA, Majoie CB, Dippel DW; MR CLEAN Investigators. Berkhemer OA, et al. N Engl J Med. 2015 Jun 11;372(24):2363. doi: 10.1056/NEJMc1504715. N Engl J Med. 2015. PMID: 26061844 No abstract available.
146 results