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5,354 results

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Page 1
Recent advances in microbial production of L-malic acid.
Wu N, Zhang J, Chen Y, Xu Q, Song P, Li Y, Li K, Liu H. Wu N, et al. Appl Microbiol Biotechnol. 2022 Dec;106(24):7973-7992. doi: 10.1007/s00253-022-12260-y. Epub 2022 Nov 12. Appl Microbiol Biotechnol. 2022. PMID: 36370160 Review.
In this review, for the first time, we comprehensively describe the methods of malic acid strain transformation, raw material utilization, malic acid separation, etc., especially recent progress and remaining challenges for industrial applications. Fir …
In this review, for the first time, we comprehensively describe the methods of malic acid strain transformation, raw material …
Microbial Biosynthesis of L-Malic Acid and Related Metabolic Engineering Strategies: Advances and Prospects.
Wei Z, Xu Y, Xu Q, Cao W, Huang H, Liu H. Wei Z, et al. Front Bioeng Biotechnol. 2021 Sep 29;9:765685. doi: 10.3389/fbioe.2021.765685. eCollection 2021. Front Bioeng Biotechnol. 2021. PMID: 34660563 Free PMC article. Review.
The technological progress in the fermentative production of malic acid is presented. Metabolic engineering strategies for malic acid production in various microorganisms are particularly reviewed. Biosynthetic pathways, transport of malic ac
The technological progress in the fermentative production of malic acid is presented. Metabolic engineering strategies for …
Efficacy of a 1% malic acid spray for xerostomia treatment: A systematic review and meta-analysis.
Liu G, Qiu X, Tan X, Miao R, Tian W, Jing W. Liu G, et al. Oral Dis. 2023 Apr;29(3):862-872. doi: 10.1111/odi.14116. Epub 2022 Jan 17. Oral Dis. 2023. PMID: 34954846 Review.
OBJECTIVES: To assess the efficacy of topical sialogogue spray containing malic acid 1% for treating xerostomia. METHODS: We searched PubMed, Cochrane Library, Embase, ClinicalTrials.gov and Web of Science databases. ...RESULTS: Five original articles involving 244 …
OBJECTIVES: To assess the efficacy of topical sialogogue spray containing malic acid 1% for treating xerostomia. METHODS: We s …
Recent advances in the production of malic acid by native fungi and engineered microbes.
Khandelwal R, Srivastava P, Bisaria VS. Khandelwal R, et al. World J Microbiol Biotechnol. 2023 Jun 3;39(8):217. doi: 10.1007/s11274-023-03666-5. World J Microbiol Biotechnol. 2023. PMID: 37269376 Review.
An additional advantage of microbial production is the synthesis of pure L-form of malic acid. Due to its numerous applications, biotechnologically- produced L-malic acid is a much sought-after platform chemical. Malic acid can be produce …
An additional advantage of microbial production is the synthesis of pure L-form of malic acid. Due to its numerous application …
Malic Acid for the Treatment of Rheumatic Diseases.
de Carvalho JF, Lerner A. de Carvalho JF, et al. Mediterr J Rheumatol. 2023 Dec 30;34(4):592-593. doi: 10.31138/mjr.301223.mar. eCollection 2023 Dec. Mediterr J Rheumatol. 2023. PMID: 38282938 Free PMC article. No abstract available.
Unveiling malic acid biorefinery: Comprehensive insights into feedstocks, microbial strains, and metabolic pathways.
Xu B, Zhang W, Zhao E, Hong J, Chen X, Wei Z, Li X. Xu B, et al. Bioresour Technol. 2024 Feb;394:130265. doi: 10.1016/j.biortech.2023.130265. Epub 2023 Dec 29. Bioresour Technol. 2024. PMID: 38160850 Review.
The review discusses microbial strains for malic acid fermentation, addressing challenges related to by-products from biomass breakdown and strategies for overcoming them. ...These insights contribute to advancing the field of consolidated bioprocessing in malic
The review discusses microbial strains for malic acid fermentation, addressing challenges related to by-products from biomass …
L-malic acid production from xylose by engineered Saccharomyces cerevisiae.
Kang NK, Lee JW, Ort DR, Jin YS. Kang NK, et al. Biotechnol J. 2022 Mar;17(3):e2000431. doi: 10.1002/biot.202000431. Epub 2021 Aug 25. Biotechnol J. 2022. PMID: 34390209
L-malic acid is widely used in the food, chemical, and pharmaceutical industries. Here, we report on production of malic acid from xylose, the second most abundant sugar in lignocellulosic hydrolysates, by engineered Saccharomyces cerevisiae. ...Additi …
L-malic acid is widely used in the food, chemical, and pharmaceutical industries. Here, we report on production of malic
Enzyme-based amperometric biosensors for malic acid - A review.
Matthews CJ, Andrews ESV, Patrick WM. Matthews CJ, et al. Anal Chim Acta. 2021 Apr 29;1156:338218. doi: 10.1016/j.aca.2021.338218. Epub 2021 Jan 21. Anal Chim Acta. 2021. PMID: 33781460 Review.
Malic acid is a key flavour component of many fruits and vegetables. There is significant interest in technologies for monitoring its concentration, particularly in winemaking. ...A particular focus of our review is the three types of malate oxidoreductase enzyme th
Malic acid is a key flavour component of many fruits and vegetables. There is significant interest in technologies for monitor
Microbial biosynthesis and secretion of l-malic acid and its applications.
Chi Z, Wang ZP, Wang GY, Khan I, Chi ZM. Chi Z, et al. Crit Rev Biotechnol. 2016;36(1):99-107. doi: 10.3109/07388551.2014.924474. Epub 2014 Jul 15. Crit Rev Biotechnol. 2016. PMID: 25025277 Review.
l-Malic acid has many uses in food, beverage, pharmaceutical, chemical and medical industries. ...However, the process for one-step fermentation is preferred as it has many advantages over any other process. The pathways of l-malic acid biosynthesis in …
l-Malic acid has many uses in food, beverage, pharmaceutical, chemical and medical industries. ...However, the process for one …
Malic Acid Improves Behavioral, Biochemical, and Molecular Disturbances in the Hypothalamus of Stressed Rats.
Koriem KMM, Tharwat HAK. Koriem KMM, et al. J Integr Neurosci. 2023 Jul 17;22(4):98. doi: 10.31083/j.jin2204098. J Integr Neurosci. 2023. PMID: 37519180 Free article.
BACKGROUND: Stress can lead to emotional and mental symptoms such as anxiety, sadness, panic attacks, and depression. Malic acid was chosen due to malic acid has the ability to improve antioxidant activity and improves liver damage. ...CMS rats were di …
BACKGROUND: Stress can lead to emotional and mental symptoms such as anxiety, sadness, panic attacks, and depression. Malic acid
5,354 results