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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 9
1948 14
1949 6
1950 10
1951 3
1952 1
1953 4
1954 2
1955 1
1956 1
1957 2
1960 4
1962 1
1963 5
1964 12
1965 7
1966 1
1967 4
1968 1
1969 5
1970 49
1971 497
1972 869
1973 927
1974 1116
1975 771
1976 794
1977 805
1978 751
1979 722
1980 805
1981 796
1982 845
1983 887
1984 1155
1985 1106
1986 1066
1987 1273
1988 1373
1989 1312
1990 1452
1991 1585
1992 1597
1993 1600
1994 1970
1995 2085
1996 2530
1997 2568
1998 2917
1999 3510
2000 4847
2001 5603
2002 5887
2003 6530
2004 7872
2005 9606
2006 10168
2007 11817
2008 12180
2009 12594
2010 13749
2011 15074
2012 15351
2013 15360
2014 15414
2015 15284
2016 14671
2017 14169
2018 13554
2019 8474
2020 398
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241,516 results
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Page 1
Mass spectrometry and protein analysis.
Domon B and Aebersold R. Science 2006 - Review. PMID 16614208
Mass spectrometry is a central analytical technique for protein research and for the study of biomolecules in general. Driven by the need to identify, characterize, and quantify proteins at ever increasing sensitivity and in ever more complex samples, a wide range of new mass spectrometry-based analytical platforms and experimental strategies have emerged. Here we review recent advances in mass spectrometry instrumentation in the context of current and emerging research strategies in protein science....
Mass spectrometry is a central analytical technique for protein research and for the study of biomolecules in general. Driven
Evolution of Orbitrap Mass Spectrometry Instrumentation.
Eliuk S and Makarov A. Annu Rev Anal Chem (Palo Alto Calif) 2015 - Review. PMID 26161972
We discuss the evolution of Orbitrap mass spectrometry (MS) from its birth in the late 1990s to its current role as one of the most prominent techniques for MS. ...We illustrate the compelling potential of Orbitrap-based mass spectrometers as (ultra) high-resolution platforms, not only for high-end proteomic applications, but also for routine targeted analysis....
We discuss the evolution of Orbitrap mass spectrometry (MS) from its birth in the late 1990s to its current role as one of the …
Introduction to mass spectrometry-based proteomics.
Matthiesen R and Bunkenborg J. Methods Mol Biol 2013. PMID 23666720
Mass spectrometry has been widely applied to study biomolecules and one rapidly developing field is the global analysis of proteins, proteomics. Understanding and handling mass spectrometry data is a multifaceted task that requires many decisions to be made to get the most comprehensive information from an experiment. ...
Mass spectrometry has been widely applied to study biomolecules and one rapidly developing field is the global analysis of pro
Forensic Mass Spectrometry.
Hoffmann WD and Jackson GP. Annu Rev Anal Chem (Palo Alto Calif) 2015 - Review. PMID 26070716
Developments in forensic mass spectrometry tend to follow, rather than lead, the developments in other disciplines. Examples of techniques having forensic potential born independently of forensic applications include ambient ionization, imaging mass spectrometry, isotope ratio mass spectrometry, portable mass spectrometers, and hyphenated chromatography-mass spectrometry instruments, to name a few. ...This review attempts to capture the trends, motivating forces, and likely impact of developing areas of forensic mass spectrometry, with the caveat that none of this research is likely to have any real impact in the forensic community unless: (a) The instruments developed are turned into robust black boxes with red and green lights for positives and negatives, respectively, or (b) there are PhD graduates in the workforce who can help adopt these sophisticated techniques....
Developments in forensic mass spectrometry tend to follow, rather than lead, the developments in other disciplines. Examples o …
[Mass spectrometry: past and present].
Király M, et al. Acta Pharm Hung 2016 - Review. PMID 27295872 Hungarian.
In the present review we briefly introduce basic mass spectrometry techniques (ion surces, analyzers), combinations with chromatography (GC/MS, HPLC/MS), CEI MS) and tandem mass spectrometry. We also introduce two novel methods, mass spectrometry "imaging" and "lab-on-a-chip" technology....
In the present review we briefly introduce basic mass spectrometry techniques (ion surces, analyzers), combinations with chrom …
DESI Mass Spectrometry Imaging (MSI).
Claude E, et al. Methods Mol Biol 2017. PMID 28523500
Desorption Electrospray Ionization (DESI) mass spectrometry is a technique that allows chemical information to be obtained directly from a wide range of surfaces. ...Here, we describe the implementation and optimization of DESI imaging for metabolites and lipids from tissue sections using oa-TOF mass spectrometers....
Desorption Electrospray Ionization (DESI) mass spectrometry is a technique that allows chemical information to be obtained dir …
A researcher's guide to mass spectrometry-based proteomics.
Savaryn JP, et al. Proteomics 2016. PMID 27553853 Free PMC article.
Mass spectrometry (MS) is widely recognized as a powerful analytical tool for molecular research. MS is used by researchers around the globe to identify, quantify, and characterize biomolecules like proteins from any number of biological conditions or sample types. ...Here, we visually describe what happens to ions as they enter and move around inside a mass spectrometer. We describe basic MS principles, including electric current, ion optics, ion traps, quadrupole mass filters, and Orbitrap FT-analyzers....
Mass spectrometry (MS) is widely recognized as a powerful analytical tool for molecular research. MS is used by researchers ar
Mass spectrometry of modified RNAs: recent developments.
Wetzel C and Limbach PA. Analyst 2016 - Review. PMID 26501195 Free PMC article.
As nearly all of these chemical modifications result in an increase in the mass of the canonical nucleoside, mass spectrometry has long been a powerful approach for identifying and characterizing modified RNAs. ...With the increasing interest in how these modifications impact the epitranscriptome, mass spectrometry will continue to play an important role in bioanalytical investigations revolving around RNA....
As nearly all of these chemical modifications result in an increase in the mass of the canonical nucleoside, mass spectrome
Biomedical mass spectrometry.
Ishii A, et al. Anal Bioanal Chem 2014. PMID 24346144
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