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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 5
2007 10
2008 19
2009 14
2010 18
2011 15
2012 16
2013 18
2014 19
2015 10
2016 12
2017 10
2018 5
2019 4
2020 0
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143 results
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Page 1
Matrix Metalloproteinase-13 - A Potential Biomarker for Detection and Prognostic Assessment of Patients with Esophageal Squamous Cell Carcinoma.
Sedighi M, et al. Asian Pac J Cancer Prev 2016. PMID 27356690 Free article.
BACKGROUND: Matric metalloproteinase (MMP) 13 gene expression is increased in esophageal squamous cell carcinomas (ESCCs) and associated with increasing tumor invasion, lymph node involvement and decreased survival rates. ...ROC analysis showed that MMP-13 level is an accurate diagnostic marker especially to differentiate pre-invasive/ invasive lesions from normal controls (sensitivity and specificity: 100%). ...
BACKGROUND: Matric metalloproteinase (MMP) 13 gene expression is increased in esophageal squamous cell carcinomas (ESCCs) and …
Serum levels of matrix metalloproteinase-13 in patients with eosinophilic fasciitis.
Asano Y, et al. J Dermatol 2014. PMID 25041217
Matrix metalloproteinase-13 (MMP-13), a member of the collagenase family, has been implicated in the pathogenesis of connective tissue diseases characterized by extracellular matrix remodeling. ...Although serum MMP-13 levels did not reflect any clinical and serological features of EF, these results indicate that MMP-13 may be involved in the development of this disease....
Matrix metalloproteinase-13 (MMP-13), a member of the collagenase family, has been implicated in the pathogenesi
The role of matrix metalloproteinases in osteoarthritis pathogenesis: An updated review.
Mehana EE, et al. Life Sci 2019 - Review. PMID 31445934
A key enzyme responsible for these degenerative changes in cartilage is matrix metalloproteinase-13 (MMP-13), which is thought to be a major contributor to the degenerative process occurring during OA pathogenesis. ...Selective inhibition of MMP-13 seems to be an attractive therapeutic strategy....
A key enzyme responsible for these degenerative changes in cartilage is matrix metalloproteinase-13 (MMP-13), wh …
Serum and knee synovial fluid matrix metalloproteinase-13 and tumor necrosis factor-alpha levels in patients with late-stage osteoarthritis.
Özler K, et al. Acta Orthop Traumatol Turc 2016. PMID 27130394 Free article.
OBJECTIVE: The aim of this study was to compare serum and synovial fluid levels of matrix metalloproteinase-13 (MMP-13) and tumor necrosis factor-alpha (TNF-α) in 2 stages of osteoarthritis, and investigate their correlation with Western Ontario and McMaster Universities Arthritis Index (WOMAC) scores. ...RESULTS: Grade 4 synovial fluid MMP-13 (4.76±5.82 pg/ml) was elevated compared to grade 3 (3.95±4.45), whereas grade 3 serum MMP-13 (1.128±0.308 pg/ml) was found elevated compared to grade 4 (1.038±0.204) (p=0.438, p=0.430, respectively). ...
OBJECTIVE: The aim of this study was to compare serum and synovial fluid levels of matrix metalloproteinase-13 (MMP- …
Krüppel-Like Factor 2 Regulates Degradation of Type II Collagen by Suppressing the Expression of Matrix Metalloproteinase (MMP)-13.
Yuan Y, et al. Cell Physiol Biochem 2017. PMID 28873368 Free article.
The aim of this study was to investigate the function of KLF2 in the inhibition of cartilage matrix destruction in chondrocytes. METHODS: RT-PCR and western blot analysis was used to determine the expression of KLF2 in human chondrocytes. Luciferase assay, ELISA assay and MMP-13 enzymatic activity assays were used to investigate the effects of KLF2 in regulating MMP-13 expression. ...
The aim of this study was to investigate the function of KLF2 in the inhibition of cartilage matrix destruction in chondrocytes. METH …
Corneal Cross-Linking Has No Effect on Matrix Metalloproteinase 9 and 13 Levels During Fungal Keratitis on the Early Stage.
Kalkanci A, et al. Mycopathologia 2018. PMID 29043533
The aim of our study was to investigate matrix metalloproteinases, MMP-9 and MMP-13 levels, in the rabbit model of Fusarium and Candida keratitis treated by corneal cross-linking (PACK-CXL). ...The difference in MMP-9 and MMP-13 levels at all groups was not statistically significant (p > 0.05). PACK-CXL with 0.25% riboflavin either alone or combined with antifungal drops was unable to provide decline in inflammatory findings in both macroscopic and microscopic levels similar to medical antifungal treatment....
The aim of our study was to investigate matrix metalloproteinases, MMP-9 and MMP-13 levels, in the rabbit model of Fusa …
Rational design of matrix metalloproteinase-13 activatable probes for enhanced specificity.
Zhu L, et al. ACS Chem Biol 2014. PMID 24266806 Free PMC article.
Because of the important roles that matrix metalloproteinases (MMPs) play in tumor invasion and metastasis, various activatable optical probes have been developed to visualize MMP activities in vitro and in vivo. Our recently developed MMP-13 activatable probe, l-MMP-P12, has been successfully applied to image the expression and inhibition of MMPs in a xenografted tumor model [Zhu, L., et al. (2011) Theranostics 1, 18-27]. ...
Because of the important roles that matrix metalloproteinases (MMPs) play in tumor invasion and metastasis, various activatabl …
Clinical significance of serum matrix metalloproteinase-13 levels in patients with esophageal squamous cell carcinoma (ESCC).
Jiao XL, et al. Eur Rev Med Pharmacol Sci 2014. PMID 24610617 Free article.
OBJECTIVES: Matrix metalloproteinase-13 (MMP13) is a highly regulated zinc-dependent endopeptidase and has been reported to be associated with vascular invasion and lymph node metastasis and predicts poor outcome for relatively early stage in esophageal squamous cell carcinoma (ESCC) patients. ...Multivariate analysis revealed that patients with an elevated level of MMP-13 (≥ 76.4 ng/ml) had significantly lower 5 year survival rate than those with non-elevated MMP-13 (< 76.4 ng/ml, log-rank p < 0.001). ...
OBJECTIVES: Matrix metalloproteinase-13 (MMP13) is a highly regulated zinc-dependent endopeptidase and has been reporte …
Increased expression of matrix metalloproteinase-13 in glioma is associated with poor overall survival of patients.
Wang J, et al. Med Oncol 2012. PMID 22351249
MMP-13 plays an important role in tumor aggressive process for it can degrade the extracellular matrix of basement membranes. ...In multivariate analysis, MMP-13 expression was proved to be an independent prognostic factor for patients with glioma (P<0.001). ...
MMP-13 plays an important role in tumor aggressive process for it can degrade the extracellular matrix of basement membranes. …
Gingival crevicular fluid matrix metalloproteinase-13 levels and molecular forms in various types of periodontal diseases.
Ilgenli T, et al. Oral Dis 2006. PMID 17054770
BACKGROUND: The purpose of this study was to evaluate the levels, molecular forms and activation degree of matrix metalloproteinase-13 (MMP-13) in the gingival crevicular fluid (GCF) of patients with periodontal diseases and to correlate these findings with periodontal clinical parameters. ...The molecular forms of MMP-13 in GCF samples were analyzed by Western immunoblotting method. Differences among the groups were assessed using non-parametric statistical analysis. ...
BACKGROUND: The purpose of this study was to evaluate the levels, molecular forms and activation degree of matrix metalloproteinas
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