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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1959 1
1989 2
1990 8
1991 14
1992 78
1993 55
1994 94
1995 97
1996 146
1997 190
1998 272
1999 312
2000 345
2001 469
2002 509
2003 588
2004 700
2005 810
2006 909
2007 949
2008 1066
2009 1196
2010 1235
2011 1397
2012 1546
2013 1553
2014 1488
2015 1484
2016 1295
2017 1190
2018 1028
2019 510
2020 12
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18,973 results
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Page 1
Matrix metalloproteinase-9 deficiency protects mice from severe influenza A viral infection.
Rojas-Quintero J, et al. JCI Insight 2018. PMID 30568032 Free PMC article.
Matrix metalloproteinase-9 (MMP-9) cleaves various proteins to regulate inflammatory and injury responses. However, MMP-9's activities during influenza A viral (IAV) infections are incompletely understood. ...
Matrix metalloproteinase-9 (MMP-9) cleaves various proteins to regulate inflammatory and injury responses. However, MMP-9's ac
Gelatinase B/Matrix Metalloproteinase-9 as Innate Immune Effector Molecule in Achalasia.
Furuzawa-Carballeda J, et al. Clin Transl Gastroenterol 2018. PMID 30449890 Free PMC article.
In view of the role of extracellular proteolysis in organ-specific autoimmunity, we studied gelatinases of the matrix metalloproteinase (MMP) family in achalasia patients. METHODS: The presence of MMP-2 and MMP-9 proteoforms was analyzed in sera of two cohorts of achalasia patients. Additionally, with the use of immunohistopathological analysis, in situ MMP-2 and MMP-9 expression was investigated. ...
In view of the role of extracellular proteolysis in organ-specific autoimmunity, we studied gelatinases of the matrix metalloprote
CD68, CD163, and matrix metalloproteinase 9 (MMP-9) co-localization in breast tumor microenvironment predicts survival differently in ER-positive and -negative cancers.
Pelekanou V, et al. Breast Cancer Res 2018. PMID 30558648 Free PMC article.
Protein expression measured by QIF was compared with mRNA expression data from the METABRIC study. RESULTS: All three macrophage markers were co-expressed, displaying higher expression in ER(-) cancers. ...In the METABRIC dataset, mRNA levels followed the co-expression pattern observed in QIF but did not always show the same trend regarding OS. ...
Protein expression measured by QIF was compared with mRNA expression data from the METABRIC study. RESULTS: All three macrophage mark …
The role of matrix metalloproteinase-9 as a prognostic biomarker in papillary thyroid cancer.
Zarkesh M, et al. BMC Cancer 2018. PMID 30509240 Free PMC article.
BACKGROUND: The aim of the present study was to investigate the association between matrix metalloproteinase-9 (MMP-9) expression with BRAF V600E mutation and clinicopathological features, in Iranian papillary thyroid cancer (PTC) patients. METHODS: In total, 90 participants including 60 PTC patients (15 males and 45 females) and 30 individuals with benign multinodular goiter (MNG) (5 males and 25 females) which were confirmed by surgical pathology, were investigated. ...
BACKGROUND: The aim of the present study was to investigate the association between matrix metalloproteinase-9 (MMP-9) express …
Interleukin-17 and matrix metalloprotease-9 expression in the mycetoma granuloma.
Siddig EE, et al. PLoS Negl Trop Dis 2019. PMID 31295246 Free PMC article.
Due to the massive immune reaction and the tissue remodeling involved, we hypothesised that the expression levels of interleukin-17 (IL-17) and matrix metalloprotease-9 (MMP-9) in the mycetoma granuloma formation were correlated to the severity of the disease and that this correlation was independent of the causative agent responsible for the granuloma reaction. ...
Due to the massive immune reaction and the tissue remodeling involved, we hypothesised that the expression levels of interleukin-17 (IL-17) …
Matrix metalloproteinase-2 and matrix metalloproteinase-9 in mice with ocular toxocariasis.
Shyu LY, et al. Parasitol Res 2019. PMID 30631927
The matrix metalloproteinase (MMP)-2 and MMP-9 activities remarkably increased, compared with those of uninfected control, by gelatin zymography and Western blot analysis in ocular toxocariasis. ...The imbalance of MMP-2/TIMP-2 and MMP-9/TIMP-1 may play a role in inflammatory cell infiltration and extracellular matrix degradation, forming granuloma, in ophthalmological pathogenesis of T. canis infection....
The matrix metalloproteinase (MMP)-2 and MMP-9 activities remarkably increased, compared with those of uninfected control, by …
Matrix metalloproteinase 9 and epileptogenesis - the crucial role of the enzyme and strategies to prevent the disease development.
Khomiak D and Kaczmarek L. Postepy Biochem 2018 - Review. PMID 30656907 Free article.
Accumulating amount of evidence from animal models and epileptic patients strongly suggest that matrix metalloproteinase 9 (MMP-9) is potentially one of the key executors of the processes of epileptogenesis. ...
Accumulating amount of evidence from animal models and epileptic patients strongly suggest that matrix metalloproteinase 9 (MM …
Matrix Metalloproteinase-9-Dependent Release of IL-1β by Human Eosinophils.
Esnault S, et al. Mediators Inflamm 2019. PMID 30906226 Free PMC article.
Using a zymography approach and pharmacological inhibitors, we identified matrix metalloproteinase-9 (MMP-9) as a protease that cleaves pro-IL-1β into a ~15 kDa form and allows the release of IL-1β from cytokine-activated eosinophils. ...
Using a zymography approach and pharmacological inhibitors, we identified matrix metalloproteinase-9 (MMP-9) as a protease tha …
Impact of Matrix Metalloproteinase 9 on COPD Development in Polish Patients: Genetic Polymorphism, Protein Level, and Their Relationship with Lung Function.
Gilowska I, et al. Biomed Res Int 2018 - Clinical Trial. PMID 30643813 Free PMC article.
Increased activity of matrix metalloproteinases (MMPs) and an imbalance between MMPs and their tissue inhibitors (TIMPs) are considered as factors influencing the pathogenesis of COPD. ...We analyzed SNP in the promoter region of MMP-9 gene (rs3918242) using PCR-RFLP method among 335 COPD patients and 309 healthy individuals. ...
Increased activity of matrix metalloproteinases (MMPs) and an imbalance between MMPs and their tissue inhibitors (TIMPs) are c …
Intracerebral matrix metalloproteinase 9 in fatal diabetic ketoacidosis.
Hoffman WH, et al. Exp Mol Pathol 2019. PMID 30986397 Free PMC article.
Recent studies report that the matrix metalloproteinase enzymes and their inhibitors are systemically activated in young Type 1 diabetes mellitus (T1D) patients during DKA and speculate on their involvement in blood-brain barrier (BBB) disruption. Based on our previous studies, we address the question if matrix metalloproteinase 9 (MMP9) is expressed in the brain in the fatal brain edema (BE) of DKA. ...
Recent studies report that the matrix metalloproteinase enzymes and their inhibitors are systemically activated in young Type …
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