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2015 1
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Page 1
Inhibition of nonalcoholic fatty liver disease in mice by selective inhibition of mTORC1.
Gosis BS, Wada S, Thorsheim C, Li K, Jung S, Rhoades JH, Yang Y, Brandimarto J, Li L, Uehara K, Jang C, Lanza M, Sanford NB, Bornstein MR, Jeong S, Titchenell PM, Biddinger SB, Arany Z. Gosis BS, et al. Science. 2022 Apr 15;376(6590):eabf8271. doi: 10.1126/science.abf8271. Epub 2022 Apr 15. Science. 2022. PMID: 35420934 Free PMC article.
Structural basis for the docking of mTORC1 on the lysosomal surface.
Rogala KB, Gu X, Kedir JF, Abu-Remaileh M, Bianchi LF, Bottino AMS, Dueholm R, Niehaus A, Overwijn D, Fils AP, Zhou SX, Leary D, Laqtom NN, Brignole EJ, Sabatini DM. Rogala KB, et al. Science. 2019 Oct 25;366(6464):468-475. doi: 10.1126/science.aay0166. Epub 2019 Oct 10. Science. 2019. PMID: 31601708 Free PMC article.
Clearing debris.
Meng D, Jewell JL. Meng D, et al. Nat Chem Biol. 2019 Aug;15(8):760-761. doi: 10.1038/s41589-019-0320-8. Nat Chem Biol. 2019. PMID: 31285594 Free PMC article.
160 results