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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1969 1
1983 2
2000 3
2001 4
2003 2
2004 5
2005 23
2006 177
2007 625
2008 742
2009 876
2010 987
2011 1097
2012 1226
2013 1404
2014 1451
2015 1460
2016 1523
2017 1528
2018 1478
2019 737
2020 18
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13,013 results
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Page 1
Mitochondrial membrane potential and reactive oxygen species in cancer stem cells.
Zhang BB, et al. Fam Cancer 2015 - Review. PMID 25266577
The metabolism heterogeneity of mitochondria in CSCs shows a big promise for cancer research. Of them, mitochondrial membrane potential (Δψm), reflecting the functional status of the mitochondrion is proved to be highly related to cancer malignancy. ...Here we shall review the mitochondrial membrane potential and reactive oxygen species of CSCs and propose the novel potential targets for cancer therapy....
The metabolism heterogeneity of mitochondria in CSCs shows a big promise for cancer research. Of them, mitochondrial membra
Mitochondrial Membrane Potential (ΔΨ) Fluctuations Associated with the Metabolic States of Mitochondria.
Teodoro JS, et al. Methods Mol Biol 2018. PMID 29850996
Consequently, alterations in electric potential across the inner mitochondrial membrane generated by differential protonic accumulation and transport is known as the mitochondrial membrane potential, or ΔΨ, and is reflective of the functional metabolic status of mitochondria. ...The evaluation of the accumulation and movements of TPP(+) across the inner mitochondrial membrane is a sensitive, immediate, accurate, and simple method of evaluation of ΔΨ in isolated, respiring mitochondria....
Consequently, alterations in electric potential across the inner mitochondrial membrane generated by differential proto …
Mitochondrial uncoupling, ROS generation and cardioprotection.
Cadenas S. Biochim Biophys Acta Bioenerg 2018 - Review. PMID 29859845 Free article.
Proton leak across the inner mitochondrial membrane increases the respiration rate and decreases the electrochemical proton gradient (Δp), and is an important mechanism for energy dissipation that accounts for up to 25% of the basal metabolic rate. ...Mitochondrial uncoupling proteins (UCPs) are able to lower the efficiency of oxidative phosphorylation and are involved in the control of mitochondrial reactive oxygen species (ROS) production. ...
Proton leak across the inner mitochondrial membrane increases the respiration rate and decreases the electrochemical proton gr …
Quantitative in vivo mapping of myocardial mitochondrial membrane potential.
Alpert NM, et al. PLoS One 2018. PMID 29338024 Free PMC article.
BACKGROUND: Mitochondrial membrane potential (ΔΨm) arises from normal function of the electron transport chain. Maintenance of ΔΨm within a narrow range is essential for mitochondrial function. ...These studies demonstrate the first in vivo application of quantitative mapping of total tissue membrane potential, ΔΨT....
BACKGROUND: Mitochondrial membrane potential (ΔΨm) arises from normal function of the electron transport chain. Mainten …
Novel methods for measuring the mitochondrial membrane potential.
Springett R. Methods Mol Biol 2015. PMID 25631015
The mitochondrial membrane potential is a critical parameter for understanding mitochondrial function, but it is challenging to quantitate with current methodologies which are based on the accumulation of cation indicators. ...Here we describe the thermodynamic framework and algorithms necessary to calculate the membrane potential from the measured oxidation states of the b-hemes....
The mitochondrial membrane potential is a critical parameter for understanding mitochondrial function, but it is …
Does Mitochondrial Fusion Require Transmembrane Potential?
Karavaeva IE, et al. Biochemistry (Mosc) 2015 - Review. PMID 26071772 Free article.
Dissipation of transmembrane potential inhibits mitochondrial fusion and thus prevents reintegration of damaged mitochondria into the mitochondrial network. Consequently, damaged mitochondria are removed by autophagy. Does transmembrane potential directly regulate the mitochondrial fusion machinery? ...
Dissipation of transmembrane potential inhibits mitochondrial fusion and thus prevents reintegration of damaged mitochondri
The Involvement of Mitochondrial Membrane Potential in Cross-Resistance Between Radiation and Docetaxel.
Kuwahara Y, et al. Int J Radiat Oncol Biol Phys 2016. PMID 27681752
JC-1 staining was used to visualize mitochondrial membrane potential. DTX-induced DNA double-strand breaks were determined by γ-H2AX staining. ...The mitochondrial membrane potential of CRR cells was lower in CRR cells than in parental cells. Depletion of mtDNA induced DTX resistance in parental cells. ...
JC-1 staining was used to visualize mitochondrial membrane potential. DTX-induced DNA double-strand breaks were determi …
Measuring Mitochondrial Membrane Potential with a Tetraphenylphosphonium-Selective Electrode.
Moreno AJ, et al. Curr Protoc Toxicol 2015. PMID 26250398
Mitochondrial bioenergetics is based on the generation of the protonmotive force by the electron transport chain. The protonmotive force is used by mitochondria for different critical aspects of its normal function, ranging from calcium accumulation to the synthesis of ATP. The transmembrane electric potential (ΔΨ) is the major component of the protonmotive force and is also the main responsible for ATP synthesis by mitochondrial ATP synthase. ...
Mitochondrial bioenergetics is based on the generation of the protonmotive force by the electron transport chain. The protonmotive fo
Measurement of mitochondrial membrane potential in leukocyte suspension by fluorescent spectroscopy.
Lobanova EG and Kondrat'eva EV. Bull Exp Biol Med 2014. PMID 24952501
A method for evaluating mitochondrial membrane potential in isolated leukocyte suspension with the use of sensitive fl uorescent cation-active dye 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethylbenzimidazolocarbocyanine (JC-1) and spectrophotometry is described. ...The method can be used for evaluation of the function of living cells and mechanisms regulating energy metabolism by evaluating the mitochondrial membrane potential....
A method for evaluating mitochondrial membrane potential in isolated leukocyte suspension with the use of sensitive fl …
Factors affecting staining to discriminate between bull sperm with greater and lesser mitochondrial membrane potential.
Gloria A, et al. Anim Reprod Sci 2018. PMID 29279197
The sperm mitochondrial membrane potential (MMP) is usually evaluated using the JC-1 dye. This study aimed to verify the effect of incubation temperature (25 °C or 38 °C), incubation time (10, 30, and 45 min), JC-1 stain concentration (0.2 μM, 2 μM, 8 μM, 12 μM), and the presence of glycerol (6.6% compared with 0%), on the capacity of the stain to discriminate between sperm with high mitochondrial membrane potential (hMMP) and low mitochondrial membrane potential (lMMP) in fresh and frozen bull sample by both flow cytometry and epifluorescence microscopy. ...
The sperm mitochondrial membrane potential (MMP) is usually evaluated using the JC-1 dye. This study aimed to verify th …
13,013 results
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