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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 12
1972 8
1973 10
1974 12
1975 8
1976 14
1977 11
1978 14
1979 15
1980 11
1981 16
1982 17
1983 24
1984 15
1985 12
1986 9
1987 9
1988 8
1989 11
1990 7
1991 13
1992 10
1993 11
1994 15
1995 15
1996 8
1997 13
1998 13
1999 9
2000 14
2001 17
2002 15
2003 13
2004 14
2005 12
2006 14
2007 11
2008 12
2009 12
2010 15
2011 16
2012 17
2013 21
2014 20
2015 13
2016 16
2017 16
2018 19
2019 15
2020 0
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619 results
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Page 1
Persistent postoperative pain after total knee arthroplasty: a prospective cohort study of potential risk factors
Rice DA, et al. Br J Anaesth 2018. PMID 30236242 Free article.
Quantitative sensory testing (pressure pain thresholds, temporal summation, conditioned pain modulation) was performed, and blood samples were obtained for subsequent genotyping of OPRM1 and COMT. ...
Quantitative sensory testing (pressure pain thresholds, temporal summation, conditioned pain modulation) was performed, and blood sam …
The Treatment of Gliomas in Adulthood
Goldbrunner R, et al. Dtsch Arztebl Int 2018 - Review. PMID 29914619 Free PMC article.
The median overall survival of patients with glioblastoma who have undergone resection of all tumor tissue with a disrupted blood-brain barrier (i.e., all contrast-enhancing tumor tissue) has been prolonged to up to 20 months. ...
The median overall survival of patients with glioblastoma who have undergone resection of all tumor tissue with a disrupted blood-bra …
Low expression of PRMT5 in peripheral blood may serve as a potential independent risk factor in assessments of the risk of stable CAD and AMI.
Tan B, et al. BMC Cardiovasc Disord 2019. PMID 30704408 Free PMC article.
BACKGROUND: Protein arginine methyltransferases (PRMTs) can catalyse the methylation of arginine and participate in many important cellular reaction processes. ...RESULTS: The results indicate that at both the RNA and protein levels, the expression levels of the PRMT5 gene in peripheral blood from patients with AMI are significantly lower than those in peripheral blood from patients with stable CAD (Z = - 4.813, P = 0.000). ...
BACKGROUND: Protein arginine methyltransferases (PRMTs) can catalyse the methylation of arginine and participate in many important ce …
Validation of a high-performance liquid chromatography method for thiopurine S-methyltransferase activity in whole blood using 6-mercaptopurine as substrate.
Rieger H, et al. Clin Chem Lab Med 2018. PMID 29194039
BACKGROUND: Variation in metabolism, toxicity and therapeutic efficacy of thiopurine drugs is largely influenced by genetic polymorphisms in the thiopurine S-methyltransferase (TPMT) gene. ...Phenotype-genotype concordance (n=300) of the whole-blood method was better when TPMT activity was expressed per volume of whole blood (specificity 92.2%), whereas correction for hematocrit resulted in lower genotype concordance (specificity 86.9%). ...
BACKGROUND: Variation in metabolism, toxicity and therapeutic efficacy of thiopurine drugs is largely influenced by genetic polymorphisms in …
Swiss cheese tragedy case study
Thin LWY. J Gastroenterol Hepatol 2018. PMID 30187547
A STUDY OF THE RELATIONSHIP BETWEEN LEVELS OF METHYLTRANSFERASES IN PERIPHERAL BLOOD MONONUCLEAR CELLS AND CHARACTERISTICS OF TUMOR IN PATIENTS WITH DUCTAL INVASIVE CARCINOMA OF BREAST.
Kankava K, et al. Georgian Med News 2016. PMID 27845283
The aim of our current pilot study is to analyze correlation of changes in the levels of methyltransferases in nuclear extracts of blood cells with some morphological and phenotypic characteristics of breast cancer. ...An opposite pattern was seen for H3K4 methyltransferase. DNMT3a level was higher in larger tumors, while the level of H3K4 methyltransferase was lowest in large tumors with significant negative correlation with the tumor size. ...
The aim of our current pilot study is to analyze correlation of changes in the levels of methyltransferases in nuclear extracts of …
Thiopurine S-methyltransferase activity in Nigerians: phenotypes and activity reference values.
Adehin A and Bolaji OO. BMC Res Notes 2018. PMID 29444714 Free PMC article.
OBJECTIVES: This study assessed the activity of thiopurine S-methyltransferase (TPMT) in Nigerians with a view to providing data on susceptibility to thiopurine toxicity, and as well generate reference activity values for clinical use. ...
OBJECTIVES: This study assessed the activity of thiopurine S-methyltransferase (TPMT) in Nigerians with a view to providing data on s …
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