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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 2
1990 3
1991 36
1992 101
1993 150
1994 158
1995 161
1996 172
1997 225
1998 211
1999 229
2000 247
2001 331
2002 361
2003 396
2004 427
2005 412
2006 406
2007 455
2008 547
2009 560
2010 651
2011 781
2012 892
2013 988
2014 1109
2015 1207
2016 1100
2017 1020
2018 1046
2019 456
2020 6
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13,315 results
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Comparison of biological features between severely immuno-deficient NOD/Shi-scid Il2rg(null) and NOD/LtSz-scid Il2rg(null) mice.
Nagatani M, et al. Exp Anim 2019. PMID 31118345 Free PMC article.
The body weight was lower in NOG mice than in NSG mice. Severe depletion of peripheral blood lymphocytes and lymphoid hypoplasia that are well-known characteristics of these mice were equally observed. ...In the adrenal, subcapsular cell hyperplasia that is known as an age-related change in non-genetically modified mice developed earlier and its incidence was higher in NSG mice than in NOG mice. ...
The body weight was lower in NOG mice than in NSG mice. Severe depletion of peripheral blood lymphocytes and lymphoid hypoplas …
Background data on NOD/Shi-scid IL-2Rγ(null) mice (NOG mice).
Kasahara K, et al. J Toxicol Sci 2017. PMID 29142168 Free article.
To obtain background data of NOD/Shi-scid IL-2Rγ(null) (NOG) mice, severely immunedeficient mice, a total of 120 animals were examined at 7, 26 and 52 weeks-old (20 mice/sex/group). ...This study provided detailed background data on NOG mice up to 52 weeks-old and provided information on appropriate use of NOG mice in the various research fields....
To obtain background data of NOD/Shi-scid IL-2Rγ(null) (NOG) mice, severely immunedeficient mice, a total of 120 animal …
Pathology of Aging in NOD scid gamma Female Mice.
Santagostino SF, et al. Vet Pathol 2017. PMID 28355107 Free PMC article.
In the past decade, NOD.Cg- Prkdc(scid) Il2rg(tm1Wjl)/SzJ (NSG, NOD scid gamma) mice have become a model of choice in several areas of biomedical research; however, comprehensive data on their spontaneous age-related pathology are not currently available in the literature. ...This study indicates that both inflammatory and neoplastic conditions contribute to morbidity and mortality in experimentally manipulated aged female NSG mice....
In the past decade, NOD.Cg- Prkdc(scid) Il2rg(tm1Wjl)/SzJ (NSG, NOD scid gamma) mice have become a model of choice in s …
Experimental cannabidiol treatment reduces early pancreatic inflammation in type 1 diabetes
Lehmann C, et al. Clin Hemorheol Microcirc 2016 - Clinical Trial. PMID 27767974
METHODS: Seven-week-old female NOD mice were prophylactically administered daily 5 mg/kg CBD or control vehicle i.p. five times weekly for ten weeks. ...RESULTS: CBD-treated NOD mice developed T1D later and showed significantly reduced leukocyte activation and increased FCD in the pancreatic microcirculation. ...
METHODS: Seven-week-old female NOD mice were prophylactically administered daily 5 mg/kg CBD or control vehicle i.p. five time …
Histidine Decarboxylase Deficiency Prevents Autoimmune Diabetes in NOD Mice.
Alkan M, et al. J Diabetes Res 2015. PMID 26090474 Free PMC article.
To this end, we used mice (inactivated) knocked out for the gene encoding histidine decarboxylase, the unique histamine-forming enzyme, backcrossed on a NOD genetic background. We found that the lack of endogenous histamine in NOD HDC(-/-) mice decreased the incidence of diabetes in relation to their wild-type counterpart. ...
To this end, we used mice (inactivated) knocked out for the gene encoding histidine decarboxylase, the unique histamine-forming enzym …
The Gut Microbiome in the NOD Mouse.
Peng J, et al. Methods Mol Biol 2016. PMID 27032947
There has recently been a major increase in studies on the association of the gut microbiome composition with disease phenotypes.The nonobese diabetic (NOD) mouse is an excellent mouse model to study spontaneous type 1 diabetes development. We, and others, have reported that gut bacteria are critical modulators for type 1 diabetes development in genetically susceptible NOD mice.Here we present our standard protocol for gut microbiome analysis in NOD mice that has been routinely implemented in our research laboratory. ...
There has recently been a major increase in studies on the association of the gut microbiome composition with disease phenotypes.The nonobes …
Presence of BPIFB1 in saliva from non-obese diabetic mice.
Nashida T, et al. Odontology 2018. PMID 28748269
In this report, we confirmed the expression of BPIFB1 protein in the parotid glands of NOD mice. Immunoblotting of subcellular fractions revealed that BPIBB1 was localised in secretory granules in parotid glands from NOD mice, and was almost not in parotid glands from the control mice. ...BPIFB1 was detected in the saliva from NOD mice but not in the saliva from the control mice, indicating individual constitution. ...
In this report, we confirmed the expression of BPIFB1 protein in the parotid glands of NOD mice. Immunoblotting of subcellular …
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