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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1957 1
1958 1
1959 2
1960 2
1962 3
1964 1
1985 1
1992 1
1993 32
1994 158
1995 346
1996 719
1997 1284
1998 1890
1999 2634
2000 3400
2001 3952
2002 4602
2003 4829
2004 5417
2005 5962
2006 6941
2007 7350
2008 7886
2009 8549
2010 9179
2011 9724
2012 9784
2013 9892
2014 9817
2015 9739
2016 9203
2017 9082
2018 8876
2019 3050
2020 42
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137,970 results
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Page 1
Type I interferon receptor knockout mice as models for infection of highly pathogenic viruses with outbreak potential.
Wong G and Qiu XG. Zool Res 2018. PMID 29511140 Free PMC article.
Due to their inability to generate a complete immune response, mice knockout for type I interferon (IFN) receptors (Ifnar(-/-)) are more susceptible to viral infections, and are thus commonly used for pathogenesis studies. ...
Due to their inability to generate a complete immune response, mice knockout for type I interferon (IFN) receptors (Ifnar(-/-) …
Knockout mice.
Majzoub JA and Muglia LJ. N Engl J Med 1996 - Review. PMID 8596575
Generation and Characterization of Fibroblast-Specific Basigin Knockout Mice.
Wu XD, et al. Mol Biotechnol 2019. PMID 30539414
The systematic Basigin gene knockout leads to the perinatal lethality of mice, which limits the delineation of its function in vivo. ...The fibroblast-specific deletion of Basigin did not influence the growth, fertility and the general condition of the mice. No obvious differences were found in the size, morphology, and histological structure of the major organs, including heart, liver, spleen, lung and kidney, between the knockout mice and the control mice. ...
The systematic Basigin gene knockout leads to the perinatal lethality of mice, which limits the delineation of its function in …
Rapid phenotyping of knockout mice to identify genetic determinants of bone strength.
Freudenthal B, et al. J Endocrinol 2016 - Review. PMID 27535945 Free PMC article.
The International Knockout Mouse Consortium (IKMC) and the International Mouse Phenotyping Consortium (IMPC) provide such an opportunity. The IKMC generates knockout mice representing each of the known protein-coding genes in C57BL/6 mice and, as part of the IMPC initiative, the Origins of Bone and Cartilage Disease project identifies mutants with significant outlier skeletal phenotypes. ...
The International Knockout Mouse Consortium (IKMC) and the International Mouse Phenotyping Consortium (IMPC) provide such an opportun …
Necessary complexity
[No authors listed] Nat Genet 2017. PMID 28747749
What have we learned about GPER function in physiology and disease from knockout mice?
Prossnitz ER and Hathaway HJ. J Steroid Biochem Mol Biol 2015 - Review. PMID 26189910 Free PMC article.
Mouse models, and in particular knockout (KO) mice, represent an important approach to understand the functions of receptors in normal physiology and disease. Whereas ERα KO mice display multiple significant defects in reproduction and mammary gland development, ERβ KO phenotypes are more limited, and GPER KO exhibit no reproductive deficits. ...
Mouse models, and in particular knockout (KO) mice, represent an important approach to understand the functions of receptors i …
[Behavioral Phenotype of Mice with Alkali Sensor IRR Gene Knockout].
Zubkov EA, et al. Zh Vyssh Nerv Deiat Im I P Pavlova 2017. PMID 30695555 Russian.
In this study, we analyzed the phenotype of IRR knockout mice in a series of behavioral tests. In control experi- ments, null-mutation littermate mice were analyzed. ...In the "Resident-intruder" test, wild-type mice demonstrated their typical aggressive behavior whereas 7 out of 16 knockout animals stayed inert and, in contrast, attacked by the intruder. ...
In this study, we analyzed the phenotype of IRR knockout mice in a series of behavioral tests. In control experi- ments, null- …
137,970 results
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