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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 25
1967 93
1968 148
1969 172
1970 180
1971 231
1972 336
1973 319
1974 373
1975 440
1976 411
1977 426
1978 434
1979 465
1980 418
1981 456
1982 514
1983 527
1984 569
1985 599
1986 609
1987 485
1988 618
1989 599
1990 660
1991 661
1992 717
1993 743
1994 752
1995 592
1996 648
1997 642
1998 713
1999 720
2000 788
2001 810
2002 823
2003 848
2004 986
2005 1117
2006 1230
2007 1282
2008 1454
2009 1330
2010 1334
2011 1511
2012 1479
2013 1443
2014 1566
2015 1394
2016 1128
2017 946
2018 787
2019 281
2020 3
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35,464 results
Results by year
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Page 1
Motor activity effects in female Fischer 344 rats exposed to isopropanol for 90 days.
Burleigh-Flayer H, et al. J Appl Toxicol 1998. PMID 9804438
These motor activity measurements were made 18-20 h following the end of the last exposure for that week. In addition, to evaluate the reversibility of motor activity effects, measurements were made on three occasions during the week following the final exposure for rats in both the 9-week and 13-week subgroups and weekly thereafter for five additional weeks for rats in the 13-week subgroup. ...No change in the shape of the motor activity habituation curve was observed at 42 days following the last exposure, indicating that complete recovery of motor activity effects had occurred. ...
These motor activity measurements were made 18-20 h following the end of the last exposure for that week. In addition, to eval …
Impact of a novel environment on alcohol-induced locomotor activity in Wistar rats.
Hernández-Vázquez F, et al. Alcohol 2018. PMID 29929089
Motor activity was recorded in naïve, saline, and alcohol-administered rats at different doses (0.1, 0.25, 0.5, 1.0, or 2.5 g/kg). ...Sensitivity to alcohol motor effects may substantially depend on the initial animal's response to a novel environment. The stimulant effects of alcohol may constitute important behavioral traits significantly associated with the rewarding properties of the drug....
Motor activity was recorded in naïve, saline, and alcohol-administered rats at different doses (0.1, 0.25, 0.5, 1.0, or 2.5 g/
Circadian phase dependency of the effects of different beta-receptor blocking drugs on motor activity of rats. Importance of drug lipophilicity.
Lemmer B and Neumann G. Arzneimittelforschung 1987. PMID 2885007
No dosage-dependency was observed in the drug effects in L. In contrast, during D a dosage-dependent decrease in motor activity was found for all compounds. ...The results clearly demonstrate a circadian phase dependency in the effects of beta-receptor blocking drugs on motor activity of rats. ...
No dosage-dependency was observed in the drug effects in L. In contrast, during D a dosage-dependent decrease in motor
Prophylactic Ketamine Attenuates Learned Fear
McGowan JC, et al. Neuropsychopharmacology 2017. PMID 28128336 Free PMC article.
It remains unknown, however, when ketamine should be administered relative to a stressor in order to maximize its antidepressant and/or prophylactic effects. ...
It remains unknown, however, when ketamine should be administered relative to a stressor in order to maximize its antidepressant and/or prop …
Revisiting the validity of the mouse forced swim test: Systematic review and meta-analysis of the effects of prototypic antidepressants.
Kara NZ, et al. Neurosci Biobehav Rev 2018 - Review. PMID 29128579
The current study presents a meta-analysis of the effects of prototypic antidepressants in the mouse forced swim test (FST). We identified studies that examined effects of antidepressants in the FST in mice and used standard protocol, male mice and acute drug administration. ...
The current study presents a meta-analysis of the effects of prototypic antidepressants in the mouse forced swim test (FST). We ident …
Motor activity: a survey of methods with potential use in toxicity testing.
Reiter LW and MacPhail RC. Neurobehav Toxicol 1979 - Review. PMID 400897
Discussion focuses on the various methods currently used to record motor activity, the various components of motor activity which are likely to be recorded, and the advantages and disadvantages of these techniques for the measurement of locomotor activity. Finally, consideration is given to studies which have compared treatment effects on motor activity derived from two or more measurement techniques....
Discussion focuses on the various methods currently used to record motor activity, the various components of motor a
Quantitative assessment of cypermethrin induced behavioural and biochemical anomalies in adult zebrafish
Nema S and Bhargava Y. Neurotoxicol Teratol 2018. PMID 29802885
Motor activity of the treated group was significantly retarded which affected their overall exploratory behaviour including their visit to the central arena of the open-field test. ...However, their freezing episodes were characterized by constant drift-like movement caused by the loss of their voluntary control over the motor coordination. ...
Motor activity of the treated group was significantly retarded which affected their overall exploratory behaviour including th
The therapy of the motor symptoms in the advanced stage of Parkinson's disease.
Takahashi K. Nihon Rinsho 2017 - Review. PMID 30566298
A number of non-dopaminergic receptors are expressed on different parts of the basal ganglia motor circuits and have become targets of PD drug development. Zonisamide, which has multimodal effects on the dopaminergic and non-dopaminergic systems, and istradefylline, the first adenosine A2A antagonist, have shown positive evidence for improved motor fluctuations....
A number of non-dopaminergic receptors are expressed on different parts of the basal ganglia motor circuits and have become targets o …
Short-Term Genetic Selection for Adolescent Locomotor Sensitivity to Delta9-Tetrahydrocannabinol (THC)
Kasten CR, et al. Behav Genet 2018. PMID 29550900 Free PMC article.
Identifying genetic targets of susceptibility to the negative effects of cannabinoid use is of growing importance. The current study sought to complete short-term selective breeding for adolescent sensitivity and resistance to the locomotor effects of a single 10 mg/kg THC dose in the open field. ...Selection for locomotor sensitivity also resulted in increased anxiety-like activity in the open field. These results are the first to indicate that adolescent THC-locomotor sensitivity can be influenced via selective breeding. ...
Identifying genetic targets of susceptibility to the negative effects of cannabinoid use is of growing importance. The current study …
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