Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

MyNCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1970 2
1971 2
1972 5
1973 4
1974 1
1975 3
1976 4
1977 5
1978 1
1979 2
1980 6
1981 2
1982 6
1983 4
1984 6
1985 4
1986 8
1987 7
1988 6
1989 4
1990 7
1991 10
1992 2
1993 5
1994 4
1995 5
1996 2
1997 9
1998 5
1999 3
2000 12
2001 7
2002 6
2003 3
2004 7
2005 9
2006 6
2007 7
2008 8
2009 7
2010 10
2011 9
2012 7
2013 6
2014 7
2015 11
2016 5
2017 15
2018 10
2019 4
2020 0
Text availability
Article attribute
Article type
Publication date

Search Results

268 results
Results by year
Filters applied: . Clear all
Page 1
REM sleep selectively prunes and maintains new synapses in development and learning
Li W, et al. Nat Neurosci 2017. PMID 28092659 Free PMC article.
Here we show that REM sleep prunes newly formed postsynaptic dendritic spines of layer 5 pyramidal neurons in the mouse motor cortex during development and motor learning. This REM sleep-dependent elimination of new spines facilitates subsequent spine formation during development and when a new motor task is learned, indicating a role for REM sleep in pruning to balance the number of new spines formed over time. ...
Here we show that REM sleep prunes newly formed postsynaptic dendritic spines of layer 5 pyramidal neurons in the mouse motor cort
Anticipatory postural adjustments and spatial organization of motor cortex: evidence of adaptive compensations in healthy older adults.
Smith JA and Fisher BE. J Neurophysiol 2018. PMID 30281380 Free article.
Here we examined if altered APAs of trunk/hip musculature in older adults are accompanied by changes in the representation of these muscles in motor cortex. ...This study indicates that altered spatial organization of motor cortex accompanies altered temporal organization of APA synergies in older adults. ...
Here we examined if altered APAs of trunk/hip musculature in older adults are accompanied by changes in the representation of these muscles …
Development of corticospinal motor excitability and cortical silent period from mid-childhood to adulthood - a navigated TMS study.
Säisänen L, et al. Neurophysiol Clin 2018. PMID 29274767
OBJECTIVES: We characterized the maturation of the excitability of the motor cortex and corticospinal tract from childhood to adulthood using electric field (EF) navigated TMS and correlated the results with manual dexterity. ...The optimal cortical representation site and resting motor threshold (rMT) were determined for the abductor pollicis brevis muscle. ...
OBJECTIVES: We characterized the maturation of the excitability of the motor cortex and corticospinal tract from childh …
Developmental profile of motor cortex transcallosal inhibition in children and adolescents.
Ciechanski P, et al. J Neurophysiol 2017. PMID 28381485 Free PMC article.
Transcallosal fibers facilitate interhemispheric networks involved in motor tasks. Despite their clinical relevance, interhemispheric motor control systems have not been completely defined in the developing brain. ...TMS was applied to the motor hotspot of the first dorsal interosseous muscle. Resting motor threshold (RMT), iSP latency, duration and suppression strength, and paired-pulse IHI were measured from both hemispheres. ...
Transcallosal fibers facilitate interhemispheric networks involved in motor tasks. Despite their clinical relevance, interhemispheric …
Unilateral nasal obstruction affects motor representation development within the face primary motor cortex in growing rats.
Abe Y, et al. J Appl Physiol (1985) 2017. PMID 28336541 Free article.
This study aimed to evaluate the effect of chronic unilateral nasal obstruction during growth on the motor representations within the face primary motor cortex (M1). ...It is possible that nasal obstruction induced the initial changes in orofacial motor behavior in response to the altered respiratory pattern, which eventually contributed to face-M1 neuroplasticity.NEW & NOTEWORTHY Unilateral nasal obstruction in rats during growth periods induced changes in arterial oxygen saturation (SpO(2)) and altered development of the motor representation within the face primary cortex. ...
This study aimed to evaluate the effect of chronic unilateral nasal obstruction during growth on the motor representations within the …
Focal Stroke in the Developing Rat Motor Cortex Induces Age- and Experience-Dependent Maladaptive Plasticity of Corticospinal System.
Gennaro M, et al. Front Neural Circuits 2017. PMID 28706475 Free PMC article.
Motor system development is characterized by an activity-dependent competition between ipsilateral and contralateral corticospinal tracts (CST). ...Here, we investigated in developing rats the relation between lesion timing, motor outcome and CST remodeling pattern. We induced a focal ischemia into forelimb motor cortex (fM1) at two distinct pre-weaning ages: P14 and P21. ...
Motor system development is characterized by an activity-dependent competition between ipsilateral and contralateral corticospinal
Age-related Differences in Pre- and Post-synaptic Motor Cortex Inhibition are Task Dependent.
Opie GM, et al. Brain Stimul 2015. PMID 25944419
OBJECTIVE: To examine age-related differences in pre- and post-synaptic motor cortex inhibition at rest, and during index finger abduction and precision grip. ...When SICI was primed by LICI, disinhibition of motor cortex was reduced in older adults at rest (100 ms ISI) and during index finger abduction (150 ms ISI), but not during precision grip. ...
OBJECTIVE: To examine age-related differences in pre- and post-synaptic motor cortex inhibition at rest, and during index fing …
Neuronal subtype-specific genes that control corticospinal motor neuron development in vivo.
Arlotta P, et al. Neuron 2005. PMID 15664173 Free article.
In order to elucidate molecular mechanisms underlying the specification and development of corticospinal motor neurons (CSMN), we purified CSMN at distinct stages of development in vivo and compared their gene expression to two other pure populations of cortical projection neurons: callosal projection neurons and corticotectal projection neurons. We found genes that are potentially instructive for CSMN development, as well as genes that are excluded from CSMN and are restricted to other populations of neurons, even within the same cortical layer. ...
In order to elucidate molecular mechanisms underlying the specification and development of corticospinal motor neurons (CSMN), …
Motor cortex maturation is associated with reductions in recurrent connectivity among functional subpopulations and increases in intrinsic excitability.
Biane JS, et al. J Neurosci 2015. PMID 25788688 Free PMC article.
Primary motor cortex slices were prepared enabling simultaneous patch-clamp recordings of up to four labeled corticospinal neurons and testing of 3489 potential synaptic connections. ...Collectively, the postnatal emergence of fine motor control is associated with a relative broadening of connectivity between functionally diverse cortical motor neurons and changes in synaptic properties that could enable the emergence of smaller independent networks, enabling fine motor movement. ...
Primary motor cortex slices were prepared enabling simultaneous patch-clamp recordings of up to four labeled corticospinal
Development of motor maps in rats and their modulation by experience.
Young NA, et al. J Neurophysiol 2012. PMID 22723681 Free article.
While a substantial literature demonstrates the effect of differential experience on development of mammalian sensory cortices and plasticity of adult motor cortex, characterization of differential experience on the functional development of motor cortex is meager. ...First, cortical GABA-mediated inhibition was depressed by bicuculline infusion directly into layer V of motor cortex and ICMS-responsive points were first reliably detected on postnatal day (PND) 13. ...
While a substantial literature demonstrates the effect of differential experience on development of mammalian sensory cortices and pl …
268 results
Jump to page
Feedback