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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 2
1966 8
1967 4
1968 11
1969 23
1970 21
1971 25
1972 31
1973 31
1974 42
1975 51
1976 62
1977 50
1978 95
1979 91
1980 79
1981 95
1982 133
1983 104
1984 117
1985 120
1986 115
1987 113
1988 110
1989 130
1990 153
1991 154
1992 156
1993 137
1994 110
1995 140
1996 165
1997 160
1998 170
1999 168
2000 254
2001 205
2002 230
2003 158
2004 144
2005 181
2006 164
2007 163
2008 201
2009 179
2010 177
2011 174
2012 161
2013 163
2014 142
2015 119
2016 117
2017 88
2018 101
2019 29
2020 0
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6,064 results
Results by year
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Page 1
Complexity of Generating Mouse Models to Study the Upper Motor Neurons: Let Us Shift Focus from Mice to Neurons.
Genc B, et al. Int J Mol Sci 2019 - Review. PMID 31394733 Free PMC article.
The cortex has special importance for motor neuron diseases, in which initiation and modulation of voluntary movement is affected. Amyotrophic lateral sclerosis (ALS) is defined by the progressive degeneration of both the upper and lower motor neurons, whereas hereditary spastic paraplegia (HSP) and primary lateral sclerosis (PLS) are characterized mainly by the loss of upper motor neurons. ...
The cortex has special importance for motor neuron diseases, in which initiation and modulation of voluntary movement is affec …
The organization of spinal motor neurons in a monotreme is consistent with a six-region schema of the mammalian spinal cord.
Mitchelle A and Watson C. J Anat 2016. PMID 27173752 Free PMC article.
A medial motor column of motor neurons is found at all spinal cord levels, and a hypaxial column is found at most levels. The organization of the motor neuron clusters in the lateral motor column of the brachial (C5 to T3) and crural (L2 to S3) limb enlargements is very similar to the pattern previously revealed by retrograde tracing in placental mammals, and the motor neuron clusters have been tentatively identified according to the muscle groups they are likely to supply. The region separating the two limb enlargements (T4 to L1) contains preganglionic motor neurons that appear to represent the spinal sympathetic outflow. ...
A medial motor column of motor neurons is found at all spinal cord levels, and a hypaxial column is found at most level …
Extracellularly identifying motor neurons for a muscle motor pool in Aplysia californica.
Lu H, et al. J Vis Exp 2013. PMID 23568081 Free PMC article.
We now describe a protocol for using this technique to uniquely identify and characterize motor neurons within a motor pool. ...This is especially useful when one tries to record multiple neurons during repeating motor patterns that may only persist for minutes. ...
We now describe a protocol for using this technique to uniquely identify and characterize motor neurons within a motor
Motor neurons and motor columns of the anterior spinal cord of salamanders: posthatching development and phylogenetic distribution.
Nishikawa KC, et al. Brain Behav Evol 1991. PMID 1913139
Direct-developing desmognathine salamanders have the plesiomorphic set of motor neurons, but appear to lack Mauthner neurons. Direct-developing plethodontine salamanders have cone-shaped, pear-shaped, and spindle-shaped neurons, but lack primary motor neurons and Mauthner neurons. ...
Direct-developing desmognathine salamanders have the plesiomorphic set of motor neurons, but appear to lack Mauthner neuron
Upregulation of anti-apoptotic factors in upper motor neurons after spinal cord injury in adult zebrafish.
Ogai K, et al. Neurochem Int 2012. PMID 22982298
Unlike mammals, fish motor function can recover within 6-8weeks after spinal cord injury (SCI). The motor function of zebrafish is regulated by dual control; the upper motor neurons of the brainstem and motor neurons of the spinal cord. ...The regrowing axons from upper motor neurons reached the lesion site at 10-15days and then crossed at 4-6weeks after SCI. These long-distance descending axons from originally axotomized neurons have a major role in restoration of motor function after SCI....
Unlike mammals, fish motor function can recover within 6-8weeks after spinal cord injury (SCI). The motor function of zebrafis …
Differentiation of spinal motor neurons from pluripotent human stem cells.
Hu BY and Zhang SC. Nat Protoc 2009. PMID 19696748 Free PMC article.
We have devised a reproducible protocol by which human embryonic stem cells (hESCs) or inducible pluripotent stem cells (iPSCs) are efficiently differentiated to functional spinal motor neurons. ...These progenitor cells further generate post-mitotic, HB9-expressing motoneurons at the 5th week and mature to functional motor neurons thereafter. ...
We have devised a reproducible protocol by which human embryonic stem cells (hESCs) or inducible pluripotent stem cells (iPSCs) are efficien …
Motor neurons supplying hindwing muscles of a grasshopper: topography and distribution into anatomical groups.
Siegler MV, et al. J Comp Neurol 1991. PMID 1955587
Stained motor neurons were examined in wholemounts and in sectioned ganglia. Two unifunctional muscles are innervated by a single motor neuron each, whereas four bifunctional muscles, involved in leg and wing movements, are innervated by two or three motor neurons each. ...Thus, motor neurons that innervate antagonistic pairs of muscles may be more similar in morphology than motor neurons that innervate synergistic muscles. ...
Stained motor neurons were examined in wholemounts and in sectioned ganglia. Two unifunctional muscles are innervated by a sin …
Master or servant? emerging roles for motor neuron subtypes in the construction and evolution of locomotor circuits.
Dasen JS. Curr Opin Neurobiol 2017 - Review. PMID 27907815 Free PMC article.
Execution of motor behaviors relies on the ability of circuits within the nervous system to engage functionally relevant subtypes of spinal motor neurons. ...Alteration in the distribution of motor neuron subtypes also appears to have contributed to evolutionary transitions in the locomotor strategies used by land vertebrates. ...
Execution of motor behaviors relies on the ability of circuits within the nervous system to engage functionally relevant subtypes of …
Neuronal development: sorting out motor neurons.
Guthrie S. Curr Biol 2002 - Review. PMID 12176348 Free article.
In the developing spinal cord, motor neurons become segregated into important functional units termed motor pools. Now it has been discovered that repertoires of cadherin surface molecules play key roles in motor pool sorting....
In the developing spinal cord, motor neurons become segregated into important functional units termed motor pools. Now …
The generation and diversification of spinal motor neurons: signals and responses.
Price SR and Briscoe J. Mech Dev 2004 - Review. PMID 15296975 Free article.
Motor neurons are probably the best characterised neuronal class in the vertebrate central nervous system and have become a paradigm for understanding the mechanisms that control the development of vertebrate neurons. ...These findings suggest that motor neuron generation is shaped by extracellular signals that regulate intrinsic, cell-autonomous determinants at sequential steps during development. ...
Motor neurons are probably the best characterised neuronal class in the vertebrate central nervous system and have beco
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