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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 6
1947 8
1948 19
1949 15
1950 25
1951 30
1952 19
1953 17
1954 12
1955 14
1956 10
1957 18
1958 11
1959 14
1960 8
1961 16
1962 31
1963 50
1964 56
1965 36
1966 41
1967 70
1968 74
1969 86
1970 92
1971 89
1972 99
1973 100
1974 90
1975 70
1976 64
1977 96
1978 77
1979 91
1980 98
1981 79
1982 127
1983 132
1984 163
1985 156
1986 139
1987 188
1988 190
1989 194
1990 244
1991 268
1992 309
1993 293
1994 328
1995 354
1996 303
1997 322
1998 339
1999 339
2000 412
2001 414
2002 366
2003 374
2004 449
2005 412
2006 497
2007 488
2008 374
2009 300
2010 299
2011 321
2012 378
2013 332
2014 299
2015 318
2016 290
2017 262
2018 288
2019 164
2020 3
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12,479 results
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Page 1
Mucins, Mucus, and Goblet Cells.
Ma J, et al. Chest 2018 - Review. PMID 29170036
The development of mice deficient in specific mucins, and the cystic fibrosis pig, has greatly advanced our understanding of the role of mucins as innate immune mediators and how mucins and mucus contribute to lung disease. ...These insights into the innate immune properties of mucins and goblet cells support a shift from the current paradigm of repressing increased mucin expression to targeting regulation of specific mucins and the abnormal airway milieu....
The development of mice deficient in specific mucins, and the cystic fibrosis pig, has greatly advanced our understanding of the role …
Mucins: the frontline defence of the lung.
Ridley C and Thornton DJ. Biochem Soc Trans 2018 - Review. PMID 30154090 Free PMC article.
This mechanism of lung defence is reliant upon a flowing mucus gel, and the major macromolecular components that determine the rheological properties of mucus are the polymeric mucins, MUC5AC and MUC5B. ...
This mechanism of lung defence is reliant upon a flowing mucus gel, and the major macromolecular components that determine the rheological p …
Mucins: the Old, the New and the Promising Factors in Hepatobiliary Carcinogenesis.
Kasprzak A and Adamek A. Int J Mol Sci 2019 - Review. PMID 30875782 Free PMC article.
Mucins are large O-glycoproteins with high carbohydrate content and marked diversity in both the apoprotein and the oligosaccharide moieties. ...Abnormal expression of mucins was observed in human carcinomas that arise in various gastrointestinal organs. It was widely believed that hepatocellular carcinoma (HCC) does not produce mucins, whereas cholangiocarcinoma (CC) or combined HCC-CC may produce these glycoproteins. ...
Mucins are large O-glycoproteins with high carbohydrate content and marked diversity in both the apoprotein and the oligosaccharide m
Cancer-associated mucins: role in immune modulation and metastasis.
Bhatia R, et al. Cancer Metastasis Rev 2019 - Review. PMID 30618016 Free PMC article.
The presence of MUC16 neo-antigen-specific T cell clones and anti-MUC1 antibodies in cancer patients suggests that mucins can serve as potential targets for developing cancer therapeutics. The present review summarizes the molecular events involved in mucin-mediated immunomodulation, and metastasis, as well as the utility of mucins as targets for cancer immunotherapy and radioimmunotherapy....
The presence of MUC16 neo-antigen-specific T cell clones and anti-MUC1 antibodies in cancer patients suggests that mucins can serve a …
Muco-Obstructive Lung Diseases
Boucher RC. N Engl J Med 2019 - Review. PMID 31091375
Mucins as multifunctional building blocks of biomaterials.
Petrou G and Crouzier T. Biomater Sci 2018 - Review. PMID 30047553
Mucins are large glycoproteins that are ubiquitous in the animal kingdom. Mucins coat the surfaces of many cell types and can be secreted to form mucus gels that assume important physiological roles in many animals. ...We offer a vision for how mucins could be used in the near future and what challenges await the field before biomaterials made of mucins and mucin-mimics can be translated into commercial products....
Mucins are large glycoproteins that are ubiquitous in the animal kingdom. Mucins coat the surfaces of many cell types and can
Mucus and Mucins: do they have a role in the inhibition of the human immunodeficiency virus?
Mall AS, et al. Virol J 2017 - Review. PMID 28985745 Free PMC article.
BACKGROUND: Mucins are large O-linked glycosylated proteins which give mucus their gel-forming properties. There are indications that mucus and mucins in saliva, breast milk and in the cervical plug inhibit the human immunodeficiency virus (HIV-1) in an in vitro assay. ...Crude saliva and its purified mucins, MUC5B and MUC7, and the purified mucins from breast milk, MUC1 and MUC4 and pregnancy plug cervical mucus (MUC2, MUC5AC, MUC5B and MUC6), inhibit HIV-1 in an in vitro assay. ...
BACKGROUND: Mucins are large O-linked glycosylated proteins which give mucus their gel-forming properties. There are indications that …
Role of mucins in lung homeostasis: regulated expression and biosynthesis in health and disease.
Symmes BA, et al. Biochem Soc Trans 2018 - Review. PMID 29802217
Mucins are massive macromolecules with numerous functional domains that contribute to their structural composition and biophysical properties. ...Glycosylation is a defining process for mucins that is specific with respect to additions of glycans to mucin apoprotein backbones, and glycan additions influence the physical properties of the mucins via structural modifications as well as charge interactions. ...
Mucins are massive macromolecules with numerous functional domains that contribute to their structural composition and biophysical pr
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