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183 results

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Page 1
Fasciculating toxicity.
Ranjan A, Jamshed N, Aggarwal P, Upadhyay V. Ranjan A, et al. Am J Emerg Med. 2019 Apr;37(4):798.e1-798.e2. doi: 10.1016/j.ajem.2019.01.033. Epub 2019 Jan 21. Am J Emerg Med. 2019. PMID: 30686539
She had perioral, tongue and lower limb fasciculations along with generalized muscle weakness with no or minimal muscarinic effects. OP poisoning with isolated nicotinic receptor mediated effect is often reported in children but in adult it is extremely rare. ...
She had perioral, tongue and lower limb fasciculations along with generalized muscle weakness with no or minimal muscarinic effect …
Organophosphorus poisoning.
Paudyal BP. Paudyal BP. JNMA J Nepal Med Assoc. 2008 Oct-Dec;47(172):251-8. JNMA J Nepal Med Assoc. 2008. PMID: 19079407 Review.
Cholinesterase reactivators, by regenerating AChE, can reverse both the nicotinic and muscarinic effects; however, this benefit has not been translated well in clinical trials. ...
Cholinesterase reactivators, by regenerating AChE, can reverse both the nicotinic and muscarinic effects; however, this benefi …
Effects of muscarinic agents on cultured human trabecular meshwork cells.
Shade DL, Clark AF, Pang IH. Shade DL, et al. Exp Eye Res. 1996 Mar;62(3):201-10. doi: 10.1006/exer.1996.0025. Exp Eye Res. 1996. PMID: 8690029
In these cells, carbachol also stimulated phosphoinositide production in a dose-dependent manner, and an antagonist profile similar to that seen for calcium response was obtained when carbachol was used as the effector. The data indicate that muscarinic effects on c …
In these cells, carbachol also stimulated phosphoinositide production in a dose-dependent manner, and an antagonist profile similar to that …
Ventilatory effects of low-dose paraoxon result from central muscarinic effects.
Houze P, Pronzola L, Kayouka M, Villa A, Debray M, Baud FJ. Houze P, et al. Toxicol Appl Pharmacol. 2008 Dec 1;233(2):186-92. doi: 10.1016/j.taap.2008.08.006. Epub 2008 Aug 14. Toxicol Appl Pharmacol. 2008. PMID: 18775447
Atropine crosses the blood-brain barrier and reverses peripheral and central muscarinic effects. In contrast, methylatropine does not cross the blood-brain barrier. Atropine completely reversed the ventilatory effects of low-dose paraoxon, while methylatropine had n …
Atropine crosses the blood-brain barrier and reverses peripheral and central muscarinic effects. In contrast, methylatropine d …
Muscarinic receptors in airways: recent developments.
Barnes PJ. Barnes PJ. J Appl Physiol (1985). 1990 May;68(5):1777-85. doi: 10.1152/jappl.1990.68.5.1777. J Appl Physiol (1985). 1990. PMID: 1972938 Review.
M3 receptors are present on airway smooth muscle and submucosal glands and mediate the classical muscarinic effects in airways. Molecular biology techniques should now allow further study of the factors that regulate transcription and expression of muscarinic recept …
M3 receptors are present on airway smooth muscle and submucosal glands and mediate the classical muscarinic effects in airways …
Muscarinic effects and foetal cardiovascular and hormonal responses in utero.
Jianli Zheng, Weili Yang, Li Cao, Shigang Li, Yuying Zhang, Zhen Wan, Caiping Mao. Jianli Zheng, et al. J Renin Angiotensin Aldosterone Syst. 2009 Sep;10(3):138-46. doi: 10.1177/1470320309104866. Epub 2009 Jun 30. J Renin Angiotensin Aldosterone Syst. 2009. PMID: 19567457 Free article.
Anti-dopaminergic and anti-muscarinic effects of dibenzodiazepines: relationship to drug induced Parkinsonism.
Miller RJ, Hiley CR. Miller RJ, et al. Naunyn Schmiedebergs Arch Pharmacol. 1976;292(3):289-93. doi: 10.1007/BF00517391. Naunyn Schmiedebergs Arch Pharmacol. 1976. PMID: 7753
The "cis" isomer of clozapine, HF-2046, was the most potent in this respect and perlapine, which is devoid of neuroleptic activity, was the weakest. 2. The anti-muscarinic effects of the same compounds were measured by using the muscarinic affinity label 3H-propylbe …
The "cis" isomer of clozapine, HF-2046, was the most potent in this respect and perlapine, which is devoid of neuroleptic activity, was the …
183 results