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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1949 1
1951 2
1952 7
1953 5
1954 15
1955 13
1956 13
1957 3
1959 6
1960 6
1961 2
1962 3
1964 4
1965 3
1966 23
1967 19
1968 20
1969 19
1970 28
1971 43
1972 73
1973 67
1974 88
1975 71
1976 137
1977 111
1978 126
1979 138
1980 166
1981 132
1982 164
1983 161
1984 140
1985 151
1986 151
1987 173
1988 195
1989 194
1990 200
1991 163
1992 200
1993 192
1994 433
1995 803
1996 967
1997 953
1998 969
1999 986
2000 1042
2001 1076
2002 1135
2003 1079
2004 1117
2005 1140
2006 1251
2007 1277
2008 1307
2009 1320
2010 1414
2011 1478
2012 1544
2013 1513
2014 1535
2015 1548
2016 1359
2017 1324
2018 1220
2019 530
2020 15
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Search Results

30,621 results
Results by year
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Page 1
Skeletal muscle excitation-metabolism coupling.
Díaz-Vegas A, et al. Arch Biochem Biophys 2019 - Review. PMID 30716283
Mitochondria represent the main source of ATP in skeletal muscle and mitochondria activity increases after muscle fiber depolarization. The regulation of mitochondrial function during contraction in skeletal muscle, however, is poorly understood. Skeletal muscle has a particular distribution of mitochondria where three distinct populations can be recognized. ...
Mitochondria represent the main source of ATP in skeletal muscle and mitochondria activity increases after muscle fiber …
Skeletal Muscle Regulates Metabolism via Interorgan Crosstalk: Roles in Health and Disease.
Argilés JM, et al. J Am Med Dir Assoc 2016 - Review. PMID 27324808 Free article.
Skeletal muscle is recognized as vital to physical movement, posture, and breathing. In a less known but critically important role, muscle influences energy and protein metabolism throughout the body. ...With loss of skeletal muscle, protein and energy availability is lowered throughout the body. Muscle loss is associated with delayed recovery from illness, slowed wound healing, reduced resting metabolic rate, physical disability, poorer quality of life, and higher health care costs. ...
Skeletal muscle is recognized as vital to physical movement, posture, and breathing. In a less known but critically important
Lipid modulation of skeletal muscle mass and function.
Lipina C and Hundal HS. J Cachexia Sarcopenia Muscle 2017 - Review. PMID 27897400 Free PMC article.
Loss of skeletal muscle mass is a characteristic feature of various pathologies including cancer, diabetes, and obesity, as well as being a general feature of ageing. ...Importantly, there is growing evidence which supports a role for fatty acids and their derived lipid intermediates in the regulation of skeletal muscle mass and function. ...
Loss of skeletal muscle mass is a characteristic feature of various pathologies including cancer, diabetes, and obesity, as we …
Skeletal muscle as a gene regulatory endocrine organ.
Karstoft K and Pedersen BK. Curr Opin Clin Nutr Metab Care 2016 - Review. PMID 27101470
PURPOSE OF REVIEW: Skeletal muscle is gaining increased attention as an endocrine organ. Recently, novel myokines and new effects of already established myokines have been identified. ...SUMMARY: Skeletal muscle is an endocrine organ which, by the release of myokines, may influence metabolism in virtually all organs in the body. ...
PURPOSE OF REVIEW: Skeletal muscle is gaining increased attention as an endocrine organ. Recently, novel myokines and new effe …
Amino Acid Sensing in Skeletal Muscle.
Moro T, et al. Trends Endocrinol Metab 2016 - Review. PMID 27444066 Free PMC article.
Aging impairs skeletal muscle protein synthesis, leading to muscle weakness and atrophy. However, the underlying molecular mechanisms remain poorly understood. ...Interventions that alleviate age-related impairments in muscle protein synthesis, strength, and/or muscle mass appear to do so by reversing age-related changes in skeletal muscle AA delivery, mTORC1 activity, and/or ATF4 activity. ...
Aging impairs skeletal muscle protein synthesis, leading to muscle weakness and atrophy. However, the underlying molecu …
Muscle as a secretory organ.
Pedersen BK. Compr Physiol 2013 - Review. PMID 23897689
Skeletal muscle is the largest organ in the body. Skeletal muscles are primarily characterized by their mechanical activity required for posture, movement, and breathing, which depends on muscle fiber contractions. However, skeletal muscle is not just a component in our locomotor system. Recent evidence has identified skeletal muscle as a secretory organ. ...
Skeletal muscle is the largest organ in the body. Skeletal muscles are primarily characterized by their mechanical acti
Skeletal muscle secretion of IL-6 is muscle type specific: Ex vivo evidence.
Liang AP, et al. Biochem Biophys Res Commun 2018. PMID 30241947 Free PMC article.
Emerging evidence indicates that skeletal muscle possesses endocrine function to secret myokines. Interleukin 6 (IL-6) is a well-characterized myokine that is involved in regulation of metabolism and muscle function. Metabolism type and contractile dynamics vary in different muscle types. It is not clear, however, if IL-6 secretion differs in different muscle types. ...
Emerging evidence indicates that skeletal muscle possesses endocrine function to secret myokines. Interleukin 6 (IL-6) is a we …
Mammalian skeletal muscle does not express functional voltage-gated H(+) channels.
Fuster C, et al. Am J Physiol Cell Physiol 2018. PMID 30281323 Free article.
High metabolic activity and existence of a large transmembrane inward electrochemical gradient for H(+) at rest promote intracellular acidification of skeletal muscle. ...Voltage-gated H(+) channels have also been found to represent another H(+) extrusion pathway in cultured muscle cells. Up to now, the skeletal muscle cell was therefore the unique vertebrate excitable cell in which voltage-gated H(+) currents have been described. ...
High metabolic activity and existence of a large transmembrane inward electrochemical gradient for H(+) at rest promote intracellular acidif …
Muscle endocrinology and its relation with nutrition.
Romagnoli C, et al. Aging Clin Exp Res 2019 - Review. PMID 30977083
Recent years have demonstrated clear evidence that skeletal muscle is an active endocrine organ. During contraction of muscle fibers, the skeletal muscle produces and releases, into the blood stream, cytokines and other peptides, called myokines, thanks to which it can both communicate with cells locally within the muscle, in an autocrine and paracrine fashion, or with other distant tissues, exerting its endocrine effects. ...This review will overview the endocrinology of the skeletal muscle, making a focus on food intake as a strategy for preventing skeletal muscle decay....
Recent years have demonstrated clear evidence that skeletal muscle is an active endocrine organ. During contraction of musc
Redox control of skeletal muscle atrophy.
Powers SK, et al. Free Radic Biol Med 2016 - Review. PMID 26912035 Free PMC article.
Skeletal muscle is also an important endocrine organ that contributes to the health of numerous body organs. Therefore, maintaining healthy skeletal muscles is important to support overall health of the body. Prolonged periods of muscle inactivity (e.g., bed rest or limb immobilization) or chronic inflammatory diseases (i.e., cancer, kidney failure, etc.) result in skeletal muscle atrophy. ...
Skeletal muscle is also an important endocrine organ that contributes to the health of numerous body organs. Therefore, mainta
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