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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1948 1
1951 2
1952 1
1953 2
1955 1
1956 3
1959 1
1960 5
1961 5
1962 2
1964 1
1965 4
1966 9
1967 11
1968 17
1969 18
1970 12
1971 20
1972 19
1973 22
1974 20
1975 14
1976 19
1977 24
1978 17
1979 22
1980 22
1981 26
1982 26
1983 33
1984 30
1985 44
1986 37
1987 34
1988 44
1989 54
1990 54
1991 50
1992 51
1993 58
1994 121
1995 197
1996 214
1997 223
1998 289
1999 256
2000 320
2001 313
2002 277
2003 313
2004 338
2005 419
2006 428
2007 424
2008 468
2009 501
2010 566
2011 616
2012 632
2013 708
2014 671
2015 705
2016 588
2017 537
2018 571
2019 272
2020 2
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Search Results

10,661 results
Results by year
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Page 1
Diseases of the skeletal muscle.
Malfatti E and Romero NB. Handb Clin Neurol 2017 - Review. PMID 28987188
After the advances created by the use of cryostat sections and histochemistry 60 years ago, muscle histopathology is now living a real renaissance. ...The objective of this chapter is to give an overview on morphology of the most frequent and recently identified muscle conditions, stressing the importance that only a combined analysis of clinical findings, muscle histology, and specific ancillary investigations is effective in reaching a precise diagnosis and orienting therapy....
After the advances created by the use of cryostat sections and histochemistry 60 years ago, muscle histopathology is now living a rea …
Correlation between peripheral skeletal muscle functions and the stable phase of COPD in older patients.
Zhang YB, et al. Eur Rev Med Pharmacol Sci 2018. PMID 30178857 Free article.
OBJECTIVE: To establish normal values for detection indexes of peripheral skeletal muscle dysfunction (quadriceps femoris) of healthy older subjects, and investigate the functional status of the peripheral skeletal muscle of patients with stable phase COPD. ...CONCLUSIONS: Chronic systemic inflammation is a major risk factor of skeletal muscle dysfunction (SMD) in COPD patients. The levels of SPD, myostatin, TWEAK, and TNF-α decreased significantly in COPD patients....
OBJECTIVE: To establish normal values for detection indexes of peripheral skeletal muscle dysfunction (quadriceps femoris) of …
Cigarette smoke directly impairs skeletal muscle function through capillary regression and altered myofibre calcium kinetics in mice.
Nogueira L, et al. J Physiol 2018. PMID 29797443 Free PMC article.
KEY POINTS: Cigarette smoke components directly alter muscle fatigue resistance and intracellular muscle fibre Ca(2+) handling independent of a change in lung structure. ...Muscle fatigue measured in situ was 50% lower in the CSE and CS groups than in control. This was accompanied by 34% and 22% decreases in soleus capillary-to-fibre ratio of the CSE and CS groups, respectively, and a trend for fewer skeletal muscle actin-positive arterioles (P = 0.07). ...
KEY POINTS: Cigarette smoke components directly alter muscle fatigue resistance and intracellular muscle fibre Ca(2+) handling …
Autophagy in skeletal muscle.
Sandri M. FEBS Lett 2010 - Review. PMID 20132819 Free article.
However, excessive protein degradation in the skeletal muscle is detrimental for the economy of the body and it can lead to death. ...However, the role and regulation of the autophagic pathway in skeletal muscle is still largely unknown. This review will focus on autophagy and discuss its beneficial or detrimental role for the maintenance of muscle mass....
However, excessive protein degradation in the skeletal muscle is detrimental for the economy of the body and it can lead to de …
Muscle pathology of hereditary motor and sensory neuropathy with proximal dominant involvement with TFG mutation.
Yamashita S, et al. Muscle Nerve 2019. PMID 31449671
RESULTS: Muscle biopsy showed myopathic pathology including fiber size variability, increased internal nuclei, fiber splitting, and core-like structures, associated with neurogenic changes: large groups of atrophic fibers and fiber type-grouping. ...Although the mechanisms underlying the skeletal muscle involvement remain to be elucidated, immunohistochemistry suggests that abnormal protein aggregation may be involved in the myopathic pathology....
RESULTS: Muscle biopsy showed myopathic pathology including fiber size variability, increased internal nuclei, fiber splitting …
Cryosectioning of Contiguous Regions of a Single Mouse Skeletal Muscle for Gene Expression and Histological Analyses.
Beedle AM. J Vis Exp 2016. PMID 28060301 Free PMC article.
With this method, consecutive cryosections are collected to enable both microscopy applications for tissue histology and enrichment of RNA for gene expression using adjacent regions from a single mouse skeletal muscle. ...However, high-quality RNA can be obtained from small samples of pooled muscle cryosections, making this method accessible for many different skeletal muscles and other tissues. ...
With this method, consecutive cryosections are collected to enable both microscopy applications for tissue histology and enrichment of RNA f …
Modeling the chemoelectromechanical behavior of skeletal muscle using the parallel open-source software library OpenCMISS.
Heidlauf T and Röhrle O. Comput Math Methods Med 2013. PMID 24348739 Free PMC article.
An extensible, flexible, multiscale, and multiphysics model for nonisometric skeletal muscle behavior is presented. The skeletal muscle chemoelectromechanical model is based on a bottom-up approach modeling the entire excitation-contraction pathway by strongly coupling a detailed biophysical model of a half-sarcomere to the propagation of action potentials along skeletal muscle fibers and linking cellular parameters to a transversely isotropic continuum-mechanical constitutive equation describing the overall mechanical behavior of skeletal muscle tissue. ...The results demonstrate the model's capability of simulating different aspects of nonisometric muscle contraction and efficiently simulating the chemoelectromechanical behavior in complex skeletal muscles such as the tibialis anterior muscle....
An extensible, flexible, multiscale, and multiphysics model for nonisometric skeletal muscle behavior is presented. The ske
Histologic changes in traumatized skeletal muscle exposed to seawater: a canine cadaver study.
Stacy BA, et al. Vet Pathol 2015. PMID 24513798
Wounds were created by incision in skeletal muscle of 2 mixed-breed canine cadavers at multiple time points from 0.5 to 74.5 hours postmortem and were exposed to artificial seawater (35 parts per thousand), 0.9% saline (8 parts per thousand), or freshwater for 24 hours before fixation for histology. ...These findings are important for evaluation of skeletal muscle injuries that are exposed to seawater, such as those occurring in marine animals, and may assist in recognizing wounds inflicted either antemortem or within the supravital period....
Wounds were created by incision in skeletal muscle of 2 mixed-breed canine cadavers at multiple time points from 0.5 to 74.5 h …
How Do Skeletal Muscles Die? An Overview.
Carmeli E, et al. Adv Exp Med Biol 2015 - Review. PMID 26017731
Clarifying the confusion regarding the term "muscle death" is of great importance, especially for clinicians. In response to various stimuli, skeletal muscle may undergo pathological changes, leading to muscle atrophy and consequently resulting in the loss of muscle strength and function. Depending on the stimulus, skeletal muscles can be induced to die through different mechanisms mainly via apoptosis, autophagy and necrosis. ...
Clarifying the confusion regarding the term "muscle death" is of great importance, especially for clinicians. In response to various …
Inflammatory Muscle Diseases.
Dalakas MC. N Engl J Med 2015. PMID 26200989
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