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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 5
1995 10
1996 32
1997 44
1998 66
1999 106
2000 100
2001 143
2002 163
2003 173
2004 173
2005 207
2006 224
2007 197
2008 183
2009 165
2010 160
2011 165
2012 173
2013 168
2014 160
2015 138
2016 139
2017 147
2018 123
2019 78
2020 2
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3,161 results
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Page 1
MutL homolog 1 expression in thyroid carcinoma and its clinical significance.
Lu Y, et al. J Cancer Res Ther 2016. PMID 28230037 Free article.
OBJECTIVE: The aim of this study was to evaluate the MutL homolog 1 (MLH1) protein expression in thyroid cancer patients and its association with clinical pathological characteristics. ...MLH1 protein expression was tested by immunohistochemical method for the 40 cancer tissues and 22 partial paired normal thyroid tissues. ...
OBJECTIVE: The aim of this study was to evaluate the MutL homolog 1 (MLH1) protein expression in thyroid cancer patients and i …
Inactivation of DNA repair triggers neoantigen generation and impairs tumour growth
Germano G, et al. Nature 2017. PMID 29186113 Free article.
Here we genetically inactivate MutL homologue 1 (MLH1) in colorectal, breast and pancreatic mouse cancer cells. The growth of MMR-deficient cells was comparable to their proficient counterparts in vitro and on transplantation in immunocompromised mice. ...
Here we genetically inactivate MutL homologue 1 (MLH1) in colorectal, breast and pancreatic mouse cancer cells. The growth of MMR-def …
Aberrant methylation of mutL homolog 1 is associated with increased risk of non-small cell lung cancer.
Hu H, et al. J Clin Lab Anal 2018. PMID 29205508 Free PMC article.
The goal of the current study was to assess the diagnostic ability of mutL homolog 1 (MLH1) promoter methylation in NSCLC. METHODS: A total of 111 NSCLC patients' paired tissue samples were obtained to explore the association between MLH1 promoter methylation and NSCLC by methylation-specific polymerase chain reaction (MSP) method. ...
The goal of the current study was to assess the diagnostic ability of mutL homolog 1 (MLH1) promoter methylation in NSCLC. METHODS: A …
Promoter methylation of human mutL homolog 1 and colorectal cancer risk: A meta-analysis.
Shi B, et al. J Cancer Res Ther 2018. PMID 29970664 Free article.
AIMS: Several studies suggested that promoter methylation of human mutL homolog 1 (hMLH1) was associated with the risk of colorectal cancer (CRC). ...
AIMS: Several studies suggested that promoter methylation of human mutL homolog 1 (hMLH1) was associated with the risk of colorectal …
Relationship Between Human mutL Homolog 1 (hMLH1) Hypermethylation and Colorectal Cancer: A Meta-Analysis.
Zhang HF, et al. Med Sci Monit 2017. PMID 28635682 Free PMC article.
Promoter hypermethylation of human mutL homolog 1 (hMLH1) has been implicated in a subset of colorectal cancers that show microsatellite instability (MSI), while the connection of the epigenetic inactivation of hMLH1 in colorectal cancers remains unknown. ...
Promoter hypermethylation of human mutL homolog 1 (hMLH1) has been implicated in a subset of colorectal cancers that show microsatell …
Association between MutL homolog 1 polymorphisms and the risk of colorectal cancer: a meta-analysis.
Chen H, et al. J Cancer Res Clin Oncol 2015. PMID 25986311
PURPOSE: As one of the most essential components of mismatch repair system, MutL homolog 1 (MLH1) plays an increasingly implicated role in initiation and promotion of colorectal carcinogenesis, with germ-line mutations in different loci. ...
PURPOSE: As one of the most essential components of mismatch repair system, MutL homolog 1 (MLH1) plays an increasingly implicated ro …
Mismatch Repair Deficiency, Microsatellite Instability, and Survival: An Exploratory Analysis of the Medical Research Council Adjuvant Gastric Infusional Chemotherapy (MAGIC) Trial
Smyth EC, et al. JAMA Oncol 2017. PMID 28241187 Free PMC article.
Tumor sections were assessed for expression of the MMR proteins mutL homologue 1, mutS homologue 2, mutS homologue 6, and PMS1 homologue 2. ...
Tumor sections were assessed for expression of the MMR proteins mutL homologue 1, mutS homologue 2, mutS homologue 6, and PMS1 …
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