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Quoted phrase not found in phrase index: "Myeloid neoplasm associated with PDGFRA rearrangement"
Page 1
Myeloid neoplasms with eosinophilia.
Reiter A, Gotlib J. Reiter A, et al. Blood. 2017 Feb 9;129(6):704-714. doi: 10.1182/blood-2016-10-695973. Epub 2016 Dec 27. Blood. 2017. PMID: 28028030 Free article. Review.
Molecular diagnostics has generated substantial dividends in dissecting the genetic basis of myeloid neoplasms with eosinophilia. The family of diseases generated by dysregulated fusion tyrosine kinase (TK) genes is recognized by the World Health Organization (WHO) …
Molecular diagnostics has generated substantial dividends in dissecting the genetic basis of myeloid neoplasms with eosinophil …
Myeloid/lymphoid neoplasms with FLT3 rearrangement.
Tang G, Tam W, Short NJ, Bose P, Wu D, Hurwitz SN, Bagg A, Rogers HJ, Hsi ED, Quesada AE, Wang W, Miranda RN, Bueso-Ramos CE, Medeiros LJ, Nardi V, Hasserjian RP, Arber DA, Orazi A, Foucar K, Wang SA. Tang G, et al. Mod Pathol. 2021 Sep;34(9):1673-1685. doi: 10.1038/s41379-021-00817-7. Epub 2021 May 14. Mod Pathol. 2021. PMID: 33990705 Free article.
However, some common features were observed, such as extramedullary involvement (n = 7, 58%), associated eosinophilia in blood, bone marrow, or tissue (n = 8, 67%), multilineage involvement, either as biphasic myeloid/lymphoid neoplasms (n = 2) or mixe …
However, some common features were observed, such as extramedullary involvement (n = 7, 58%), associated eosinophilia in blood …
Clinical and Molecular Approach to Adult-Onset, Neoplastic Monocytosis.
Shallis RM, Siddon AJ, Zeidan AM. Shallis RM, et al. Curr Hematol Malig Rep. 2021 Jun;16(3):276-285. doi: 10.1007/s11899-021-00632-6. Epub 2021 Apr 22. Curr Hematol Malig Rep. 2021. PMID: 33890194 Review.
The absence of a TET2, SRSF2, or ASXL1 mutation has 90% negative predictive value for a diagnosis of CMML. These data may also reliably differentiate chronic myelomonocytic leukemia, the malignancy that is most associated with mature monocytosis, from several other …
The absence of a TET2, SRSF2, or ASXL1 mutation has 90% negative predictive value for a diagnosis of CMML. These data may also reliab …
Primary eosinophilic disorders: a concise review.
Pardanani A, Tefferi A. Pardanani A, et al. Curr Hematol Malig Rep. 2008 Jan;3(1):37-43. doi: 10.1007/s11899-008-0007-9. Curr Hematol Malig Rep. 2008. PMID: 20425445 Review.
Primary eosinophilic disorders include hypereosinophilic syndrome (HES); chronic eosinophilic leukemia, not otherwise categorized (CEL-NOC); platelet-derived growth factor receptor (PDGFR)-rearranged myeloid neoplasms; and other myeloid malignancies …
Primary eosinophilic disorders include hypereosinophilic syndrome (HES); chronic eosinophilic leukemia, not otherwise categorized (CEL-NOC); …
Ligand-dependent platelet-derived growth factor receptor (PDGFR)-alpha activation sensitizes rare lung cancer and sarcoma cells to PDGFR kinase inhibitors.
McDermott U, Ames RY, Iafrate AJ, Maheswaran S, Stubbs H, Greninger P, McCutcheon K, Milano R, Tam A, Lee DY, Lucien L, Brannigan BW, Ulkus LE, Ma XJ, Erlander MG, Haber DA, Sharma SV, Settleman J. McDermott U, et al. Cancer Res. 2009 May 1;69(9):3937-46. doi: 10.1158/0008-5472.CAN-08-4327. Epub 2009 Apr 14. Cancer Res. 2009. PMID: 19366796 Free PMC article.
Activation of PDGFR signaling has been described in gastrointestinal stromal tumors (PDGFRA mutations) as well as in chronic myeloid leukemia (BCR-PDGFRA translocation), and sunitinib can yield clinical benefit in both settings. ...These two cell lines [a non …
Activation of PDGFR signaling has been described in gastrointestinal stromal tumors (PDGFRA mutations) as well as in chronic myelo …