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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 7
1997 9
1998 5
1999 9
2000 9
2001 9
2002 8
2003 3
2004 4
2005 7
2006 5
2007 5
2008 10
2009 8
2010 8
2011 12
2012 13
2013 8
2014 9
2015 4
2016 11
2017 12
2018 11
2019 3
2020 0
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171 results
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Page 1
NADPH oxidases as drug targets and biomarkers in neurodegenerative diseases: What is the evidence?
Sorce S, et al. Free Radic Biol Med 2017 - Review. PMID 28811143 Free article.
NADPH oxidases (NOX) emerged as a novel promising class of pharmacological targets for the treatment of neurodegeneration due to their role in oxidant generation and presumably in regulating microglia activation. ...We address the possibility to use measurement of the activity of the NOX2 isoform in blood samples as biomarker of disease severity and treatment efficacy in neurodegenerative disease. ...
NADPH oxidases (NOX) emerged as a novel promising class of pharmacological targets for the treatment of neurodegeneration due
Spectrophotometric assays for measuring redox biomarkers in blood and tissues: the NADPH network.
Veskoukis AS, et al. Redox Rep 2018 - Review. PMID 29088980
The main aim of this review is to collectively present the NADPH-related molecules, namely NADPH, NADH, NAD(+) kinase, NADPH oxidase, peroxiredoxin, thioredoxin, thioredoxin reductase, and nitric oxide synthase, that can be measured in blood and tissues with the use of a spectrophotometer, which is probably the most simple, inexpensive and widely used tool in biochemistry. We are providing the researchers with reliable and valid spectrophotometric assays for the measurement of the most important biomarkers of the NADPH network in blood and other tissues, thus allowing the opportunity to follow the redox changes in response to a stimulus....
The main aim of this review is to collectively present the NADPH-related molecules, namely NADPH, NADH, NAD(+) kinase, NADP
Serum NADPH oxidase concentrations and the associations with iron metabolism in relapsing remitting multiple sclerosis.
Doğan HO and Yildiz ÖK. J Trace Elem Med Biol 2019. PMID 31345363
Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases are the primary sources of regulated ROS production. The NADPH oxidase (NOX) family consists of seven catalytic homologues, NOX1-5 and two dual oxidases. ...Serum NOX1,4,5, ferritin, iron, unbound-iron binding capacity, C-reactive protein (CRP), white blood count (WBC) and erythrocyte sedimentation rate (ESR) levels were measured in all the study subjects. ...
Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases are the primary sources of regulated ROS production. The NADPH
NADPH oxidase 2 (NOX2): A key target of oxidative stress-mediated platelet activation and thrombosis.
Fuentes E, et al. Trends Cardiovasc Med 2018 - Review. PMID 29661712
Platelet ROS are mostly generated by reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase. NOX2 is an isoform from NADPH oxidase expressed in platelets and an important regulator of platelet activation-associated thrombosis. ...
Platelet ROS are mostly generated by reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase. NOX2 is an isoform from …
Effect of oral CoQ10 supplementation along with precooling strategy on cellular response to oxidative stress in elite swimmers
Emami A and Bazargani-Gilani B. Food Funct 2018 - Clinical Trial. PMID 30058646
Blood sampling was carried out pre- and post- (two stages) administration of CoQ10 along with precooling with heavy trainings. ...No desired effect of the precooling strategy was found on the serum levels of NADPH-oxidase, CK, LA, 8-iso PGF2α, 8-OHdG, H2O2, AST, PC, ALT, and GGT....
Blood sampling was carried out pre- and post- (two stages) administration of CoQ10 along with precooling with heavy trainings. ...No
A stable nonfluorescent derivative of resorufin for the fluorometric determination of trace hydrogen peroxide: applications in detecting the activity of phagocyte NADPH oxidase and other oxidases.
Zhou M, et al. Anal Biochem 1997. PMID 9367498
When applied to the measurement of NADPH oxidase activation, the Amplex Red assay can detect H2O2 release from as few as 2000 phorbol myristate acetate-stimulated neutrophils with a sensitivity 5- to 20-fold greater than that attained in the scopoletin assay under the same experimental conditions. ...
When applied to the measurement of NADPH oxidase activation, the Amplex Red assay can detect H2O2 release from as few as 2000 phorbol …
Residual NADPH oxidase and survival in chronic granulomatous disease.
Kuhns DB, et al. N Engl J Med 2010. PMID 21190454 Free PMC article.
Expression of NADPH oxidase component protein was detected by means of immunoblotting, and the affected genes were sequenced to identify causal mutations. ...The production of residual ROI is predicted by the specific NADPH oxidase mutation, regardless of the specific gene affected, and it is a predictor of survival in patients with chronic granulomatous disease. ...
Expression of NADPH oxidase component protein was detected by means of immunoblotting, and the affected genes were sequenced to ident …
Passive Smoking Exacerbates Nicotinamide-Adenine Dinucleotide Phosphate Oxidase Isoform 2-Induced Oxidative Stress and Arterial Dysfunction in Children with Persistent Allergic Rhinitis
Loffredo L, et al. J Pediatr 2018. PMID 30172425
A cross-sectional study was performed to compare endothelial function by flow-mediated dilation, blood levels of isoprostanes, serum activity of soluble NOX2-dp (sNOX2-dp), and nitric oxide bioavailability, in these 2 groups of children. ...
A cross-sectional study was performed to compare endothelial function by flow-mediated dilation, blood levels of isoprostanes, serum …
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