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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 1
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1952 1
1957 2
1958 5
1962 2
1963 10
1964 40
1965 34
1967 3
1968 3
1969 5
1970 4
1971 8
1972 5
1973 5
1974 7
1975 12
1976 9
1977 4
1978 26
1979 18
1980 11
1981 8
1982 27
1983 26
1984 64
1985 76
1986 89
1987 92
1988 78
1989 40
1990 34
1991 33
1992 59
1993 46
1994 37
1995 45
1996 60
1997 82
1998 99
1999 104
2000 154
2001 111
2002 79
2003 101
2004 94
2005 84
2006 78
2007 104
2008 107
2009 111
2010 127
2011 136
2012 134
2013 141
2014 158
2015 170
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2017 128
2018 147
2019 54
2020 1
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Naphthyridines part 4: unprecedented synthesis of polyfunctionally substituted benzo[c][2,7]naphthyridines and benzo[c]pyrimido[4,5,6-ij][2,7]naphthyridines with structural analogy to pyrido[4,3,2-mn]acridines present in the marine tetracyclic pyridoacridine alkaloids.
Mekheimer RA, et al. Mol Divers 2018. PMID 29164475
An easy, efficient and one-step synthesis of the versatile, hitherto unreported of polyfunctionally substituted benzo[c][2,7]naphthyridines 4a-c is described. ...Lastly, diazotization of 10a-c afforded the novel tetracyclic ring system 3,6-dialkyl-2-oxo-3,6-dihydro-2H-benzo[c][1,2,3]triazino[4,5,6-ij][2,7]naphthyridine-1-carbonitriles 16a-c....
An easy, efficient and one-step synthesis of the versatile, hitherto unreported of polyfunctionally substituted benzo[c][2,7]naphthyridin
Synthesis and photocytotoxic activity of [1,2,3]triazolo[4,5-h][1,6]naphthyridines and [1,3]oxazolo[5,4-h][1,6]naphthyridines.
Frasson I, et al. Eur J Med Chem 2019. PMID 30445266
[1,2,3]Triazolo[4,5-h][1,6]naphthyridines and [1,3]oxazolo[5,4-h][1,6]naphthyridines were synthesized with the aim to investigate their photocytotoxic activity. ...
[1,2,3]Triazolo[4,5-h][1,6]naphthyridines and [1,3]oxazolo[5,4-h][1,6]naphthyridines were synthesized with the aim to investig …
Naphthyridines with Antiviral Activity - A Review.
Singh IP, et al. Med Chem 2017 - Review. PMID 28031019
Antiviral activity displayed by many naphthyridine analogs is in nM range. Only few review articles are available in literature which describe about various biological activities of naphthyridines, but there is no comprehensive compilation particularly for antiviral activities. ...CONCLUSION: This review will be helpful for future researches to design and synthesize naphthyridine analogs with improved antiviral activities....
Antiviral activity displayed by many naphthyridine analogs is in nM range. Only few review articles are available in literature which …
Multistep regulation of TFEB by MTORC1
Vega-Rubin-de-Celis S, et al. Autophagy 2017. PMID 28055300 Free PMC article.
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