Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

MyNCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 117
2003 136
2004 157
2005 169
2006 155
2007 109
2008 115
2009 169
2010 212
2011 222
2012 214
2013 198
2014 213
2015 213
2016 273
2017 276
2018 257
2019 233
2020 42
Text availability
Article attribute
Article type
Publication date

Search Results

3,381 results
Results by year
Filters applied: . Clear all
Page 1
mRNA vaccines - a new era in vaccinology
Pardi N, et al. Nat Rev Drug Discov 2018 - Review. PMID 29326426 Free PMC article.
Drug repurposing: progress, challenges and recommendations.
Pushpakom S, et al. Nat Rev Drug Discov 2019 - Review. PMID 30310233
Various data-driven and experimental approaches have been suggested for the identification of repurposable drug candidates; however, there are also major technological and regulatory challenges that need to be addressed. In this Review, we present approaches used for drug repurposing (also known as drug repositioning), discuss the challenges faced by the repurposing community and recommend innovative ways by which these challenges could be addressed to help realize the full potential of drug repurposing....
Various data-driven and experimental approaches have been suggested for the identification of repurposable drug candidates; ho …
Targeting the NLRP3 inflammasome in inflammatory diseases
Mangan MSJ, et al. Nat Rev Drug Discov 2018 - Review. PMID 30026524
Although these findings highlight the potential of NLRP3 as a drug target, an understanding of NLRP3 structure and activation mechanisms is incomplete, which has hampered the discovery and development of novel therapeutics against this target. ...
Although these findings highlight the potential of NLRP3 as a drug target, an understanding of NLRP3 structure and activation mechani …
Kinase inhibitors: the road ahead
Ferguson FM and Gray NS. Nat Rev Drug Discov 2018 - Review. PMID 29545548
Kinase inhibitor drug discovery programmes have recently broadened their focus to include an expanded range of kinase targets and therapeutic areas. ...
Kinase inhibitor drug discovery programmes have recently broadened their focus to include an expanded range of kinase targets and the …
Mitochondria as a therapeutic target for common pathologies
Murphy MP and Hartley RC. Nat Rev Drug Discov 2018 - Review. PMID 30393373
Mitochondria therefore represent an important drug target for these highly prevalent diseases. Several strategies aimed at therapeutically restoring mitochondrial function are emerging, and a small number of agents have entered clinical trials. ...
Mitochondria therefore represent an important drug target for these highly prevalent diseases. Several strategies aimed at therapeuti …
Delivery technologies for cancer immunotherapy
Riley RS, et al. Nat Rev Drug Discov 2019 - Review. PMID 30622344 Free PMC article.
The number of immunotherapy drug approvals has been increasing, with numerous treatments in clinical and preclinical development. ...Advanced biomaterials and drug delivery systems, such as nanoparticles and the use of T cells to deliver therapies, could effectively harness immunotherapies and improve their potency while reducing toxic side effects. ...
The number of immunotherapy drug approvals has been increasing, with numerous treatments in clinical and preclinical development. ... …
3,381 results
Jump to page
Feedback