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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 8
1946 16
1947 18
1948 19
1949 19
1950 1
1951 32
1952 73
1953 56
1954 70
1955 75
1956 63
1957 59
1958 57
1959 59
1960 60
1961 56
1962 32
1963 2
1964 6
1965 85
1966 135
1967 146
1968 206
1969 242
1970 206
1971 235
1972 210
1973 247
1974 196
1975 214
1976 206
1977 205
1978 220
1979 231
1980 187
1981 261
1982 241
1983 216
1984 225
1985 216
1986 236
1987 265
1988 248
1989 243
1990 293
1991 294
1992 326
1993 328
1994 289
1995 284
1996 307
1997 311
1998 325
1999 292
2000 342
2001 317
2002 346
2003 349
2004 339
2005 381
2006 421
2007 375
2008 451
2009 412
2010 411
2011 489
2012 436
2013 447
2014 443
2015 421
2016 443
2017 413
2018 442
2019 233
2020 5
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Page 1
Worm Infections in Children.
Weatherhead JE and Hotez PJ. Pediatr Rev 2015 - Review. PMID 26232464
• On the basis of research evidence, worm infections are important global child health conditions causing chronic disability that lasts from childhood into adulthood (Table 1). (2)(3) Evidence Quality: B • On the basis of research evidence, the major worm infections found in developing countries include ascariasis, trichuriasis, hookworm infection, and schistosomiasis; toxocariasis, enterobiasis, and cysticercosis are also found in poor regions of North America and Europe. (4)(9)(13) Evidence Quality: B • On the basis of expert consensus, children and adolescents are often vulnerable to acquiring large numbers of worms, ie, high-intensity infections (Fig 1)(21)(22)(23) Evidence Quality: D • On the basis of expert consensus and research evidence, moderate and heavy worm burdens cause increased morbidity because of growth and intellectual stunting in children and adolescents. Many of these effects may result from helminth-induced malnutrition. (21)(22)(23) Evidence Quality: C • On the basis of expert consensus and research evidence, worm infections are also commonly associated with eosinophilia. (48) (49) Evidence Quality: B • On the basis of research evidence as well as consensus, helminthes can cause inflammation in the lung (asthma), gastrointestinal tract (enteritis and colitis), liver (hepatitis and fibrosis), and urogenital tract. (7)(21)(22)(23)(27)(28)(40)(41)(43) Evidence Quality: B • On the basis of research evidence, microscopy techniques for diagnosis of worm infections in children often exhibit suboptimal sensitivities and specificities, necessitating new or improved diagnostic modalities such as polymerase chain reaction. (54)(55) Evidence Quality: A • On the basis of research evidence and expert consensus, mass drug administration (“preventive chemotherapy”) has becomea standard practice for ministries of health in low- and middle-income countries to control intestinal helminth infections and schistosomiasis. (67)(68) Evidence Quality: B....
• On the basis of research evidence, worm infections are important global child health conditions causing chronic disability that las …
Integrated control of nematode infections in cattle: a reality? A need? A future?
Vercruysse J and Dorny P. Int J Parasitol 1999 - Review. PMID 10048829
Helminth infections are a major cause of production loss in cattle. Great progress has been achieved in the design of control strategies for these infections. ...
Helminth infections are a major cause of production loss in cattle. Great progress has been achieved in the design of control strateg …
Mebendazole
Keystone JS and Murdoch JK. Ann Intern Med 1979. PMID 484964
The drug's poor absorption does not appear to affect clinical efficacy except in the treatment of systemic helminth infections. Mebendazole has been found to be ovicidal for the eggs of roundworm, hookworm, and whipworm with the disadvantages of cost and long duration of therapy; it is also considered the best drug for the treatment of trichuriasis. ...
The drug's poor absorption does not appear to affect clinical efficacy except in the treatment of systemic helminth infections. Meben …
Worm Control in Livestock: Bringing Science to the Field
Kenyon F, et al. Trends Parasitol 2017 - Review. PMID 28647171
Parasitic roundworm infections are ubiquitous in grazing livestock. Chemical control through the frequent 'blanket' administration of anthelmintics (wormers) has been, and remains, the cornerstone in controlling these infections, but this practice is unsustainable. ...
Parasitic roundworm infections are ubiquitous in grazing livestock. Chemical control through the frequent 'blanket' administration of …
Eradicating Filariasis
Pai-Dhungat J. J Assoc Physicians India 2018. PMID 30347967
Evaluation of the efficacy of pyrantel-oxantel for the treatment of soil-transmitted nematode infections.
Albonico M, et al. Trans R Soc Trop Med Hyg 2002 - Clinical Trial. PMID 12625151 Free PMC article.
A randomized controlled trial comparing the efficacy of pyrantel-oxantel (10 mg/kg) with mebendazole (500 mg) was performed on 1329 schoolchildren aged 6-9 years on Pemba Island in September-October 2000 to evaluate alternative single-dose drugs for regular treatment of intestinal nematode infections. ...Pyrantel-oxantel (10 mg/kg) offers a valuable alternative to mebendazole as a single-dose treatment for the control of intestinal nematode infections in children in endemic areas of sub-Saharan Africa, due to its comparable efficacy, its low cost and its suitability for use in young children....
A randomized controlled trial comparing the efficacy of pyrantel-oxantel (10 mg/kg) with mebendazole (500 mg) was performed on 1329 schoolch …
Preventive chemotherapy in one year reduces by over 80% the number of individuals with soil-transmitted helminthiases causing morbidity: results from meta-analysis
Marocco C, et al. Trans R Soc Trop Med Hyg 2017 - Review. PMID 28340144 Free PMC article.
The morbidity due to Ascaris lumbricoides and Trichuris trichiura is caused by infections of moderate and heavy intensity while hookworm infections of all intensities are recognized to cause morbidity. This study aims to evaluate the effect of repeated rounds of preventive chemotherapy on the proportion of soil-transmitted helminth (STH) infections causing morbidity. ...
The morbidity due to Ascaris lumbricoides and Trichuris trichiura is caused by infections of moderate and heavy intensity while hookw …
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