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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2003 2
2004 2
2005 3
2006 2
2007 3
2008 9
2009 8
2010 98
2011 281
2012 336
2013 406
2014 362
2015 313
2016 317
2017 309
2018 272
2019 92
2020 0
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2,490 results
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Page 1
Neural Subtype Specification from Human Pluripotent Stem Cells.
Tao Y and Zhang SC. Cell Stem Cell 2016 - Review. PMID 27814479 Free PMC article.
Human pluripotent stem cells (hPSCs) provide a model to study early neural development, model pathological processes, and develop therapeutics. ...Further development to promote faster maturation or aging as well as circuit integration will help realize the potential of hPSC-derived neural cells in disease modeling and cell therapy....
Human pluripotent stem cells (hPSCs) provide a model to study early neural development, model pathological processes, a …
Isolation and Culture of Embryonic Mouse Neural Stem Cells.
Homayouni Moghadam F, et al. J Vis Exp 2018. PMID 30474636
Neural stem cells (NSCs) are multipotent and can give rise to the three major cell types of the central nervous system (CNS). ...There are several reported techniques for the isolation of neural stem cells from adult or embryo mammalian brains. During the microsurgical operation to isolate NSCs from different regions of the embryonic CNS, it is very important to reduce the damage to the brain cells to obtain the highest ratio of live and expandable stem cells. ...
Neural stem cells (NSCs) are multipotent and can give rise to the three major cell types of the central nervous system
Neural Stem Cells.
Tuazon JP, et al. Adv Exp Med Biol 2019 - Review. PMID 31898782
Neural stem cell (NSC) transplantation has provided the basis for the development of potentially powerful new therapeutic cell-based strategies for a broad spectrum of clinical diseases, including stroke, psychiatric illnesses such as fetal alcohol spectrum disorders, and cancer. ...
Neural stem cell (NSC) transplantation has provided the basis for the development of potentially powerful new therapeutic cell
Neural Stem Cells Derived Directly from Adipose Tissue.
Petersen ED, et al. Stem Cells Dev 2018. PMID 29649413
Neural stem cells (NSCs) are characterized as self-renewing cell populations with the ability to differentiate into the multiple tissue types of the central nervous system. ...Adult tissue is a more practical source of stem cells for transplantation therapies in humans. Some adult tissues such as adipose tissue and bone marrow contain a wide variety of stem cell populations, some of which have been shown to be similar to embryonic stem cells, possessing many pluripotent properties. ...
Neural stem cells (NSCs) are characterized as self-renewing cell populations with the ability to differentiate into the
Direct reprogramming of fibroblasts into neural stem cells by single non-neural progenitor transcription factor Ptf1a.
Xiao D, et al. Nat Commun 2018. PMID 30030434 Free PMC article.
Induced neural stem cells (iNSCs) reprogrammed from somatic cells have great potentials in cell replacement therapies and in vitro modeling of neural diseases. Direct conversion of fibroblasts into iNSCs has been shown to depend on a couple of key neural progenitor transcription factors (TFs), raising the question of whether such direct reprogramming can be achieved by non-neural progenitor TFs. ...
Induced neural stem cells (iNSCs) reprogrammed from somatic cells have great potentials in cell replacement ther …
Neural stem cells in the adult spinal cord.
Sabelström H, et al. Exp Neurol 2014 - Review. PMID 23376590
Work over the last few years has identified neural stem cells and delineated the stem cell potential of different cell populations in the adult spinal cord under homeostasis and in response to injury. Neural stem cell properties are contained within the ependymal cell population, and these cells generate the majority of new astrocytes forming the glial scar. ...
Work over the last few years has identified neural stem cells and delineated the stem cell potential of differen …
Comparison of 2D and 3D neural induction methods for the generation of neural progenitor cells from human induced pluripotent stem cells.
Chandrasekaran A, et al. Stem Cell Res 2017. PMID 29128818 Free article.
Neural progenitor cells (NPCs) from human induced pluripotent stem cells (hiPSCs) are frequently induced using 3D culture methodologies however, it is unknown whether spheroid-based (3D) neural induction is actually superior to monolayer (2D) neural induction. ...Electron microscopy demonstrated that both methods resulted in morphologically similar neural rosettes. However, quantification of NPCs derived from 3D neural induction exhibited an increase in the number of PAX6/NESTIN double positive cells and the derived neurons exhibited longer neurites. ...
Neural progenitor cells (NPCs) from human induced pluripotent stem cells (hiPSCs) are frequently induced using 3
Derivation of Neural Stem Cells from the Developing and Adult Human Brain.
Kelly CM and Caldwell MA. Results Probl Cell Differ 2018. PMID 30209653
Neural stem cells isolated from the developing and adult brain are an ideal source of cells for use in clinical applications such as cell replacement therapy. ...Foetal neural stem cells can be readily derived from the foetal brain and expand in culture over time. Similarly, adult stem cells have been explored for their potential in vitro and in vivo animal models. ...
Neural stem cells isolated from the developing and adult brain are an ideal source of cells for use in clinical
Human Fetal Neural Stem Cells for Neurodegenerative Disease Treatment.
Ferrari D, et al. Results Probl Cell Differ 2018. PMID 30209666
Clinical trials for Parkinson's disease, which used primary brain fetal tissue, have demonstrated that neural stem cell therapy could be suitable for neurodegenerative diseases. ...Here we describe a well-established protocol to produce human neural stem cells following GMP guidelines that allows us to obtain "clinical grade" cell lines....
Clinical trials for Parkinson's disease, which used primary brain fetal tissue, have demonstrated that neural stem cell therap …
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