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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 1
1949 1
1952 4
1953 13
1954 9
1955 17
1956 9
1957 10
1958 9
1959 17
1960 34
1961 28
1962 18
1965 38
1966 37
1967 64
1968 62
1969 62
1970 55
1971 61
1972 54
1973 55
1974 59
1975 66
1976 76
1977 70
1978 80
1979 70
1980 82
1981 96
1982 109
1983 139
1984 132
1985 151
1986 211
1987 239
1988 258
1989 280
1990 270
1991 337
1992 328
1993 389
1994 362
1995 340
1996 468
1997 466
1998 510
1999 461
2000 578
2001 586
2002 561
2003 534
2004 628
2005 745
2006 967
2007 1061
2008 1146
2009 1316
2010 1473
2011 1722
2012 1743
2013 1775
2014 1743
2015 1788
2016 1590
2017 1522
2018 1654
2019 572
2020 2
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Search Results

27,419 results
Results by year
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Page 1
Pathology of Neurodegenerative Diseases.
Dugger BN and Dickson DW. Cold Spring Harb Perspect Biol 2017 - Review. PMID 28062563 Free PMC article.
Neurodegenerative diseases can be classified according to primary clinical features (e.g., dementia, parkinsonism, or motor neuron disease), anatomic distribution of neurodegeneration (e.g., frontotemporal degenerations, extrapyramidal disorders, or spinocerebellar degenerations), or principal molecular abnormality. ...In this review, we detail the human pathology of select neurodegenerative disorders, focusing on their main protein aggregates....
Neurodegenerative diseases can be classified according to primary clinical features (e.g., dementia, parkinsonism, or motor ne
Neurodegenerative diseases.
Heemels MT. Nature 2016. PMID 27830810
Role of neuroinflammation in neurodegenerative diseases (Review).
Chen WW, et al. Mol Med Rep 2016 - Review. PMID 26935478 Free PMC article.
Neurodegeneration is observed after viral insult and mostly in various so-called 'neurodegenerative diseases', generally observed in the elderly, such as Alzheimer's disease, multiple sclerosis, Parkinson's disease and amyotrophic lateral sclerosis that negatively affect mental and physical functioning. ...In this review, we investigated the role played by the inflammatory process in neurodegenerative diseases....
Neurodegeneration is observed after viral insult and mostly in various so-called 'neurodegenerative diseases', generall
Oxidative Stress in Neurodegenerative Diseases.
Niedzielska E, et al. Mol Neurobiol 2016 - Review. PMID 26198567 Free PMC article.
The pathophysiologies of neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), Parkinson's disease (PD), and Alzheimer's disease (AD), are far from being fully explained. ...In this article, we review the current knowledge regarding the involvement of OS in neurodegenerative diseases, based on clinical trials and animal studies. ...
The pathophysiologies of neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), Parkinson's disease (PD), …
Neurodegenerative Diseases and Ageing.
Walker L, et al. Subcell Biochem 2019 - Review. PMID 30888650
This chapter describes the main neuropathological features of the most common age associated neurodegenerative diseases including Alzheimer's disease, Lewy body diseases, vascular dementia and the various types of frontotemporal lobar degeneration. ...The main aim of this chapter is to inform the reader about the neuropathological basics of age associated neurodegenerative diseases as we feel this is crucial to meaningfully interpret the vast literature that is published in the broad field of dementia research....
This chapter describes the main neuropathological features of the most common age associated neurodegenerative diseases includ …
Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration.
Deczkowska A, et al. Cell 2018 - Review. PMID 29775591 Free article.
A major challenge in the field of neurodegenerative diseases and brain aging is to identify the body's intrinsic mechanism that could sense the central nervous system (CNS) damage early and protect the brain from neurodegeneration. Accumulating evidence suggests that disease-associated microglia (DAM), a recently identified subset of CNS resident macrophages found at sites of neurodegeneration, might play such a protective role. ...
A major challenge in the field of neurodegenerative diseases and brain aging is to identify the body's intrinsic mechanism tha …
Neurodegenerative diseases: model organisms, pathology and autophagy.
Suresh SN, et al. J Genet 2018 - Review. PMID 30027903 Free article.
A proteostasis view of neurodegeneration (ND) identifies protein aggregation as a leading causative reason for damage seen at the cellular and organ levels. ...
A proteostasis view of neurodegeneration (ND) identifies protein aggregation as a leading causative reason for damage seen at the cel …
Glycation, Glycolysis, and Neurodegenerative Diseases: Is There Any Connection?
Muronetz VI, et al. Biochemistry (Mosc) 2017 - Review. PMID 28941455
This review considers the interrelation between different types of protein glycation, glycolysis, and the development of amyloid neurodegenerative diseases. ...In our opinion, the modification of aggregates and fibrils is secondary in nature and does not play an important role in the development of neurodegenerative diseases. ...
This review considers the interrelation between different types of protein glycation, glycolysis, and the development of amyloid neurodeg
Tauopathies
Kovacs GG. Handb Clin Neurol 2017 - Review. PMID 28987182
Tauopathies are neurodegenerative disorders characterized by the deposition of abnormal tau protein in the brain. The spectrum of tau pathologies expands beyond the traditionally discussed disease forms like Pick disease, progressive supranuclear palsy, corticobasal degeneration, and argyrophilic grain disease. ...
Tauopathies are neurodegenerative disorders characterized by the deposition of abnormal tau protein in the brain. The spectrum of tau …
Autophagy in health and disease: A comprehensive review
Saha S, et al. Biomed Pharmacother 2018 - Review. PMID 29800913
Autophagy, a conserved catabolic process, plays an immensely significant role in a variety of diseases. However, whether it imparts a protective function in diseases remains debatable. ...Similarly, in neurodegenerative disorders, accumulation of tau and synuclein proteins has been attributed to the decline in the autophagic removal of proteins. ...
Autophagy, a conserved catabolic process, plays an immensely significant role in a variety of diseases. However, whether it imparts a …
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