Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

MyNCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 9
2002 25
2003 17
2004 17
2005 15
2006 17
2007 25
2008 22
2009 21
2010 27
2011 23
2012 25
2013 28
2014 28
2015 27
2016 25
2017 20
2018 21
2019 9
2020 0
Text availability
Article attribute
Article type
Publication date

Search Results

360 results
Results by year
Filters applied: . Clear all
Page 1
Lipid binding promotes the open conformation and tumor-suppressive activity of neurofibromin 2.
Chinthalapudi K, et al. Nat Commun 2018. PMID 29626191 Free PMC article.
Neurofibromatosis type 2 (NF2) is a tumor-forming disease of the nervous system caused by deletion or by loss-of-function mutations in NF2, encoding the tumor suppressing protein neurofibromin 2 (also known as schwannomin or merlin). Neurofibromin 2 is a member of the ezrin, radixin, moesin (ERM) family of proteins regulating the cytoskeleton and cell signaling. ...
Neurofibromatosis type 2 (NF2) is a tumor-forming disease of the nervous system caused by deletion or by loss-of-function muta
Role of Merlin/NF2 inactivation in tumor biology
Petrilli AM and Fernández-Valle C. Oncogene 2016 - Review. PMID 25893302 Free PMC article.
Merlin (Moesin-ezrin-radixin-like protein, also known as schwannomin) is a tumor suppressor protein encoded by the neurofibromatosis type 2 gene NF2. Loss of function mutations or deletions in NF2 cause neurofibromatosis type 2 (NF2), a multiple tumor forming disease of the nervous system. ...
Merlin (Moesin-ezrin-radixin-like protein, also known as schwannomin) is a tumor suppressor protein encoded by the neurofibromatosis
NF2/Merlin Inactivation and Potential Therapeutic Targets in Mesothelioma
Sato T and Sekido Y. Int J Mol Sci 2018 - Review. PMID 29587439 Free PMC article.
The neurofibromatosis type 2 (NF2) gene encodes merlin, a tumor suppressor protein frequently inactivated in schwannoma, meningioma, and malignant mesothelioma (MM). ...
The neurofibromatosis type 2 (NF2) gene encodes merlin, a tumor suppressor protein frequently inactivated in schwannoma, menin …
Genetic landscape of meningioma
Yuzawa S, et al. Brain Tumor Pathol 2016 - Review. PMID 27624470
Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP
Liu-Chittenden Y, et al. Genes Dev 2012. PMID 22677547 Free PMC article.
We show that a dominant-negative TEAD molecule does not perturb normal liver growth but potently suppresses hepatomegaly/tumorigenesis resulting from YAP overexpression or Neurofibromin 2 (NF2)/Merlin inactivation. ...
We show that a dominant-negative TEAD molecule does not perturb normal liver growth but potently suppresses hepatomegaly/tumorigenesis resul …
A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis
Moroishi T, et al. Genes Dev 2015. PMID 26109050 Free PMC article.
Here, we show that YAP/TAZ activation results in activation of their negative regulators, LATS1/2 (large tumor suppressor 1/2) kinases, to constitute a negative feedback loop of the Hippo pathway in both cultured cells and mouse tissues. ...Furthermore, YAP/TAZ also stimulate the kinase activity of LATS1/2 through inducing NF2 (neurofibromin 2). This feedback regulation is responsible for the transient activation of YAP upon lysophosphatidic acid (LPA) stimulation and the inhibition of YAP-induced cell migration. ...
Here, we show that YAP/TAZ activation results in activation of their negative regulators, LATS1/2 (large tumor suppressor 1/2) …
NF2 Activates Hippo Signaling and Promotes Ischemia/Reperfusion Injury in the Heart
Matsuda T, et al. Circ Res 2016. PMID 27402866 Free PMC article.
RATIONALE: NF2 (neurofibromin 2) is an established tumor suppressor that promotes apoptosis and inhibits growth in a variety of cell types, yet its function in cardiomyocytes remains largely unknown. ...
RATIONALE: NF2 (neurofibromin 2) is an established tumor suppressor that promotes apoptosis and inhibits growth in a variety o …
360 results
Jump to page
Feedback