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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1956 1
1957 8
1958 19
1959 12
1965 17
1966 25
1967 27
1968 44
1969 47
1970 27
1971 36
1972 28
1973 18
1974 30
1975 18
1976 21
1977 29
1978 8
1979 13
1980 19
1981 16
1982 21
1983 12
1984 12
1985 11
1986 12
1987 13
1988 11
1989 8
1990 5
1991 8
1992 13
1993 5
1994 12
1995 8
1996 5
1997 5
1998 4
1999 10
2000 6
2001 7
2002 7
2003 5
2004 10
2005 5
2006 9
2007 11
2008 10
2009 12
2010 11
2011 15
2012 14
2013 17
2014 17
2015 18
2016 11
2017 12
2018 13
2019 6
2020 0
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831 results
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Page 1
Nitrofurantoin's efficacy and safety as prophylaxis for urinary tract infections: a systematic review of the literature and meta-analysis of controlled trials.
Muller AE, et al. Clin Microbiol Infect 2017 - Review. PMID 27542332 Free article.
When compared with no prophylaxis, nitrofurantoin is effective in the prevention of UTI (risk ratio 0.38 in favour of nitrofurantoin, 95% CI 0.30-0.48). ...Its use may be associated with increased non-severe adverse effects; severe adverse effects occur infrequently. The risk of severe toxicity seems to increase with the duration of nitrofurantoin prophylaxis....
When compared with no prophylaxis, nitrofurantoin is effective in the prevention of UTI (risk ratio 0.38 in favour of nitrofuranto
Nitrofurantoin revisited: a systematic review and meta-analysis of controlled trials.
Huttner A, et al. J Antimicrob Chemother 2015 - Review. PMID 26066581
OBJECTIVES: Nitrofurantoin's use has increased exponentially since recent guidelines repositioned it as first-line therapy for uncomplicated lower urinary tract infection (UTI). ...Acquisition of resistance to nitrofurantoin is still relatively rare. CONCLUSIONS: When given short term for lower UTI, nitrofurantoin has good clinical and microbiological efficacy; toxicity is mild and predominantly gastrointestinal....
OBJECTIVES: Nitrofurantoin's use has increased exponentially since recent guidelines repositioned it as first-line therapy for …
Five-day nitrofurantoin is better than single-dose fosfomycin at resolving UTI symptoms.
[No authors listed] Drug Ther Bull 2018 - Clinical Trial. PMID 30297448
Review of: Huttner A et al Effect of 5-day nitrofurantoin vs single dose fosfomycin on clinical resolution of uncomplicated lower urinary tract infection in women. ...
Review of: Huttner A et al Effect of 5-day nitrofurantoin vs single dose fosfomycin on clinical resolution of uncomplicated lower uri …
Nitrofurantoin vs other prophylactic agents in reducing recurrent urinary tract infections in adult women: a systematic review and meta-analysis.
Price JR, et al. Am J Obstet Gynecol 2016 - Review. PMID 27457111
Daily antibiotic use is the recommended strategy for recurrent urinary tract infection prevention. Increasing antibiotic resistance rates, however, require immediate identification of innovative alternative prophylactic therapies. ...Randomized control trials of women with recurrent urinary tract infections comparing nitrofurantoin with any other treatment were included. ...
Daily antibiotic use is the recommended strategy for recurrent urinary tract infection prevention. Increasing antibiotic resistance r …
Nitrofurantoin contraindication in patients with a creatinine clearance below 60 mL/min: looking for the evidence.
Oplinger M and Andrews CO. Ann Pharmacother 2013 - Review. PMID 23341159
OBJECTIVE: To investigate the evidence leading to nitrofurantoin contraindication in patients with a creatinine clearance (CrCl) below 60 mL/min. ...Concerns of increased risks of serious adverse reactions in patients with reduced renal function have further limited the use of nitrofurantoin. ...
OBJECTIVE: To investigate the evidence leading to nitrofurantoin contraindication in patients with a creatinine clearance (CrCl) belo …
Kidney function and the use of nitrofurantoin to treat urinary tract infections in older women.
Singh N, et al. CMAJ 2015. PMID 25918178 Free PMC article.
However, a similar risk of treatment failure with nitrofurantoin was also observed among women with relatively high estimated glomerular filtration rate. ...INTERPRETATION: In this study, the presence of mild or moderate reductions in estimated glomerular filtration rate did not justify avoidance of nitrofurantoin....
However, a similar risk of treatment failure with nitrofurantoin was also observed among women with relatively high estimated glomeru …
Nitrofurantoin safety and effectiveness in treating acute uncomplicated cystitis (AUC) in hospitalized adults with renal insufficiency: antibiotic stewardship implications.
Cunha BA, et al. Eur J Clin Microbiol Infect Dis 2017. PMID 28155015
However, there have been concerns regarding decreased nitrofurantoin efficacy with renal insufficiency. In our experience over the past three decades, nitrofurantoin has been safe and effective in treating AUC in hospitalized adults with renal insufficiency. Accordingly, we retrospectively reviewed our recent experience treating AUC in hospitalized adults with decreased renal function (CrCl < 60 ml/min) with nitrofurantoin. ...
However, there have been concerns regarding decreased nitrofurantoin efficacy with renal insufficiency. In our experience over the pa …
Nitrofurantoin.
D'Arcy PF. Drug Intell Clin Pharm 1985 - Review. PMID 3896715
For more than 30 years nitrofurantoin has been a widely prescribed and effective agent in the treatment of urinary tract infections. ...Reports on interactions of nitrofurantoin with alcohol, antacids, and oral contraceptives are unfounded and anecdotal. Interactions with nalidixic and oxolinic acids are not clinically significant, and only one case of interaction has been reported with phenytoin. ...
For more than 30 years nitrofurantoin has been a widely prescribed and effective agent in the treatment of urinary tract infections. …
Nitrofurantoin--current concepts.
Cunha BA. Urology 1988 - Review. PMID 3291373
One drug which has managed to avoid such resistance problems in its thirty years of use is nitrofurantoin. Nitrofurantoin is effective therapeutically for the treatment of acute lower tract infections, chronic UTI, and for the suppression of catheter-associated bacteria. ...Adverse drug reactions, especially pulmonary toxicity, are extremely rare, and nitrofurantoin maintains an excellent safety profile....
One drug which has managed to avoid such resistance problems in its thirty years of use is nitrofurantoin. Nitrofurantoin
Nitrofurantoin.
[No authors listed] Lancet 1971. PMID 4107403
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