Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

MyNCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1999 1
2000 1
2001 11
2002 35
2003 19
2004 41
2005 39
2006 52
2007 49
2008 58
2009 67
2010 81
2011 90
2012 95
2013 77
2014 62
2015 91
2016 100
2017 75
2018 68
2019 42
2020 2
Text availability
Article attribute
Article type
Publication date

Search Results

1,031 results
Results by year
Filters applied: . Clear all
Page 1
The nuclear pore complex: understanding its function through structural insight.
Beck M and Hurt E. Nat Rev Mol Cell Biol 2017 - Review. PMID 27999437
Nuclear pore complexes (NPCs) fuse the inner and outer nuclear membranes to form channels across the nuclear envelope. They are large macromolecular assemblies with a complex composition and diverse functions. ...
Nuclear pore complexes (NPCs) fuse the inner and outer nuclear membranes to form channels across the nuclear env
The Nuclear Pore Complex as a Flexible and Dynamic Gate.
Knockenhauer KE and Schwartz TU. Cell 2016 - Review. PMID 26967283 Free PMC article.
Nuclear pore complexes (NPCs) perforate the nuclear envelope and serve as the primary transport gates for molecular exchange between nucleus and cytoplasm. ...
Nuclear pore complexes (NPCs) perforate the nuclear envelope and serve as the primary transport gates for molecular exc
Moonlighting nuclear pore proteins: tissue-specific nucleoporin function in health and disease.
Jühlen R and Fahrenkrog B. Histochem Cell Biol 2018 - Review. PMID 30361777
The nuclear pore complex is the main transportation hub for exchange between the cytoplasm and the nucleus. It is built from nucleoporins that form distinct subcomplexes to establish this huge protein complex in the nuclear envelope. ...On the other hand, nucleoporins forming the scaffold structure of the nuclear pore complex are eminently mutation-prone. These novel and exciting associations between nucleoporins and human diseases emphasize the need to shed light on these unanticipated tissue-specific roles of nucleoporins that may go well beyond their role in nucleocytoplasmic transport. ...
The nuclear pore complex is the main transportation hub for exchange between the cytoplasm and the nucleus. It is built from n …
Mutations in multiple components of the nuclear pore complex cause nephrotic syndrome.
Braun DA, et al. J Clin Invest 2018. PMID 30179222 Free PMC article.
Recently, it was discovered that mutations of NUP93 and NUP205, encoding 2 proteins of the inner ring subunit of the nuclear pore complex (NPC), cause SRNS. ...We furthermore found that CRISPR/Cas9 knockout of NUP107, NUP85, or NUP133 in podocytes activated Cdc42, an important effector of SRNS pathogenesis. ...
Recently, it was discovered that mutations of NUP93 and NUP205, encoding 2 proteins of the inner ring subunit of the nuclear pore
Nuclear Pore Complex Components in the Malaria Parasite Plasmodium berghei.
Kehrer J, et al. Sci Rep 2018. PMID 30050042 Free PMC article.
The nuclear pore complex (NPC) is a large macromolecular assembly of around 30 different proteins, so-called nucleoporins (Nups). Embedded in the nuclear envelope the NPC mediates bi-directional exchange between the cytoplasm and the nucleus and plays a role in transcriptional regulation that is poorly understood. ...
The nuclear pore complex (NPC) is a large macromolecular assembly of around 30 different proteins, so-called nucleoporins (Nup …
Aberrant distributions of nuclear pore complex proteins in ALS mice and ALS patients.
Shang J, et al. Neuroscience 2017. PMID 28344074
Nuclear pore complexes (NPCs) play important roles in traffic of molecules between the nucleus and cytoplasm, aberrant distributions of components of NPCs were demonstrated in C9orf72 amyotrophic lateral sclerosis (C9-ALS) patients, but it is elusive whether such abnormities are also the case with other cause of ALS disease. ...Double immunofluorescent analysis showed abnormal nuclear retention and apparent co-localizations of RanGAPl with NUP205 and NUP205 with NUPl07, meanwhile, GP210 with NUP205 mainly co-localized in the nuclear envelope (NE) of motor neurons. ...
Nuclear pore complexes (NPCs) play important roles in traffic of molecules between the nucleus and cytoplasm, aberrant distrib
Nuclear pore proteins and the control of genome functions.
Ibarra A and Hetzer MW. Genes Dev 2015 - Review. PMID 25691464 Free PMC article.
Nuclear pore complexes (NPCs) are composed of several copies of ∼30 different proteins called nucleoporins (Nups). NPCs penetrate the nuclear envelope (NE) and regulate the nucleocytoplasmic trafficking of macromolecules. ...Nups play an evolutionarily conserved role in gene expression regulation that, in metazoans, extends into the nuclear interior. ...
Nuclear pore complexes (NPCs) are composed of several copies of ∼30 different proteins called nucleoporins (Nups). NPCs penetr
Nup153 Unlocks the Nuclear Pore Complex for HIV-1 Nuclear Translocation in Nondividing Cells.
Buffone C, et al. J Virol 2018. Among authors: Pornillos O. PMID 29997211 Free PMC article.
Interaction of the HIV-1 capsid with Nup153 and CPSF6 is important for nuclear entry and integration; however, the contribution of each of these proteins to nuclear import and integration is not clear. ...This work demonstrates that integration site selection is a multiparameter process that depends upon nuclear factors and the state of the cellular chromatin....
Interaction of the HIV-1 capsid with Nup153 and CPSF6 is important for nuclear entry and integration; however, the contribution of ea …
Cilia and Nuclear Pore Proteins: Pore No More?
Obado SO and Rout MP. Dev Cell 2016. PMID 27623377 Free article.
Nuclear pore proteins at the base of cilia were thought to regulate transport into cilia. In this issue of Developmental Cell, Del Viso et al. (2016) challenge this view, showing instead that pore proteins localize to ciliary basal bodies and that their perturbation leads to congenital heart disease....
Nuclear pore proteins at the base of cilia were thought to regulate transport into cilia. In this issue of Developmental Cell,
The nuclear pore complex: a strategic platform for regulating cell signaling.
Gu Y. New Phytol 2018 - Review. PMID 28858378 Free article.
Conclusions 29 Acknowledgements 29 References 29 SUMMARY: Nuclear pore complexes (NPCs) are fundamental components of the eukaryotic cell. ...Recent studies illustrate that the NPC is not a static structural channel but a flexible environment and strategic player during nuclear signaling. ...
Conclusions 29 Acknowledgements 29 References 29 SUMMARY: Nuclear pore complexes (NPCs) are fundamental components of the euka …
1,031 results
Jump to page
Feedback