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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 1
1993 6
1994 274
1995 704
1996 878
1997 1064
1998 1338
1999 1646
2000 2111
2001 2497
2002 2935
2003 3370
2004 4098
2005 4921
2006 5376
2007 6079
2008 6846
2009 7391
2010 8218
2011 8772
2012 9747
2013 10096
2014 10415
2015 10877
2016 11045
2017 11409
2018 11515
2019 6327
2020 157
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130,260 results
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Page 1
Oxidative stress: a concept in redox biology and medicine.
Sies H. Redox Biol 2015 - Review. PMID 25588755 Free PMC article.
"Oxidative stress" as a concept in redox biology and medicine has been formulated in 1985; at the beginning of 2015, approx. 138,000 PubMed entries show for this term. ...The field of oxidative stress research embraces chemistry, biochemistry, cell biology, physiology and pathophysiology, all the way to medicine and health and disease research....
"Oxidative stress" as a concept in redox biology and medicine has been formulated in 1985; at the beginning of 2015, approx. 1 …
Oxidative stress and mitochondrial dysfunction-linked neurodegenerative disorders.
Islam MT. Neurol Res 2017 - Review. PMID 27809706
In addition, oxidative stress causing protein misfold may turn to other NDDs include Creutzfeldt-Jakob disease, Bovine Spongiform Encephalopathy, Kuru, Gerstmann-Straussler-Scheinker syndrome, and Fatal Familial Insomnia. An overview of the oxidative stress and mitochondrial dysfunction-linked NDDs has been summarized in this review....
In addition, oxidative stress causing protein misfold may turn to other NDDs include Creutzfeldt-Jakob disease, Bovine Spongif …
Oxidative stress and antioxidants in hypertension-a current review.
Sinha N and Dabla PK. Curr Hypertens Rev 2015 - Review. PMID 26022210
Oxidative stress is a result of imbalance between the generation of reactive oxygen species (ROS) and the antioxidant defence systems. ...Results in humans are still less conclusive inspite of data available that involve oxidative stress as a causative factor of essential hypertension. ...
Oxidative stress is a result of imbalance between the generation of reactive oxygen species (ROS) and the antioxidant defence
A systematic review of p53 regulation of oxidative stress in skeletal muscle.
Beyfuss K and Hood DA. Redox Rep 2018 - Review. PMID 29298131
The role of p53 in the cell is determined by the type of imposed oxidative stress, its intensity and duration. The last decade of research has unravelled a dual nature in the function of p53 in mediating the oxidative stress burden. ...With low to moderate levels of oxidative stress, p53 is involved in activating pathways that increase time for cell repair, such as cell cycle arrest and autophagy, to enhance cell survival. ...
The role of p53 in the cell is determined by the type of imposed oxidative stress, its intensity and duration. The last decade …
Oxidative stress in health and disease: the therapeutic potential of Nrf2 activation.
Hybertson BM, et al. Mol Aspects Med 2011 - Review. PMID 22020111 Free article.
For the past 40 years or so, oxidative stress has been increasingly recognized as a contributing factor in aging and in various forms of pathophysiology generally associated with aging. ...In the last decade our view of oxidative stress has broadened considerably, and it is now often seen as an imbalance that has its origins in our genes, and the ways in which gene expression is regulated. ...
For the past 40 years or so, oxidative stress has been increasingly recognized as a contributing factor in aging and in variou …
Nutrient Sensing and the Oxidative Stress Response.
Luo H, et al. Trends Endocrinol Metab 2017 - Review. PMID 28314502 Free PMC article.
Recent advances in nutrient sensing have provided molecular insights into the oxidative stress response and suggest that CR triggers an active defense program involving a cascade of molecular regulators to reduce oxidative stress. Physiological studies have provided strong support for oxidative stress in the development of aging-associated conditions and diseases but have also revealed the surprising requirement for oxidative stress to support normal physiological functions and, in some contexts, even slow aging and prevent the progression of cancer. ...
Recent advances in nutrient sensing have provided molecular insights into the oxidative stress response and suggest that CR tr …
Oxidative stress and pathophysiology of ischemic stroke: novel therapeutic opportunities.
Rodrigo R, et al. CNS Neurol Disord Drug Targets 2013 - Review. PMID 23469845
Thus, it is critical to investigate antioxidant strategies that lead to the diminution of oxidative injury. The antioxidant vitamins C and E, the polyphenol resveratrol, the xanthine oxidase [XO] inhibitor allopurinol, and other antioxidant strategies have been reviewed in the setting of strokes. This review focuses on the mechanisms involved in ROS generation, the role of oxidative stress in the pathogenesis of ischemic stroke, and the novel therapeutic strategies to be tested to reduce the cerebral damage related to both ischemia and reperfusion....
Thus, it is critical to investigate antioxidant strategies that lead to the diminution of oxidative injury. The antioxidant vitamins …
Nutrients and Oxidative Stress: Friend or Foe?
Tan BL, et al. Oxid Med Cell Longev 2018 - Review. PMID 29643982 Free PMC article.
There are different types of nutritionally mediated oxidative stress sources that trigger inflammation. Much information indicates that high intakes of macronutrients can promote oxidative stress and subsequently contribute to inflammation via nuclear factor-kappa B- (NF-κB-) mediated cell signaling pathways. ...However, the molecular mechanisms of nutritionally mediated oxidative stress are complex and poorly understood. Therefore, this review aimed to explore how dietary choices exacerbate or dampen the oxidative stress and inflammation. ...
There are different types of nutritionally mediated oxidative stress sources that trigger inflammation. Much information indic …
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