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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 2
2004 12
2005 12
2006 28
2007 43
2008 53
2009 42
2010 46
2011 61
2012 79
2013 105
2014 161
2015 216
2016 300
2017 361
2018 338
2019 216
2020 22
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1,839 results
Results by year
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Page 1
Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome.
Schwartz GG, Steg PG, Szarek M, Bhatt DL, Bittner VA, Diaz R, Edelberg JM, Goodman SG, Hanotin C, Harrington RA, Jukema JW, Lecorps G, Mahaffey KW, Moryusef A, Pordy R, Quintero K, Roe MT, Sasiela WJ, Tamby JF, Tricoci P, White HD, Zeiher AM; ODYSSEY OUTCOMES Committees and Investigators. Schwartz GG, et al. N Engl J Med. 2018 Nov 29;379(22):2097-2107. doi: 10.1056/NEJMoa1801174. Epub 2018 Nov 7. N Engl J Med. 2018. PMID: 30403574 Clinical Trial.
Clinical Pharmacokinetics and Pharmacodynamics of Evolocumab, a PCSK9 Inhibitor.
Kasichayanula S, Grover A, Emery MG, Gibbs MA, Somaratne R, Wasserman SM, Gibbs JP. Kasichayanula S, et al. Clin Pharmacokinet. 2018 Jul;57(7):769-779. doi: 10.1007/s40262-017-0620-7. Clin Pharmacokinet. 2018. PMID: 29353350 Free PMC article. Review.
The Evolving Future of PCSK9 Inhibitors.
Rosenson RS, Hegele RA, Fazio S, Cannon CP. Rosenson RS, et al. J Am Coll Cardiol. 2018 Jul 17;72(3):314-329. doi: 10.1016/j.jacc.2018.04.054. Epub 2018 Jul 9. J Am Coll Cardiol. 2018. PMID: 30012326 Free article. Review.
In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model.
Carreras A, Pane LS, Nitsch R, Madeyski-Bengtson K, Porritt M, Akcakaya P, Taheri-Ghahfarokhi A, Ericson E, Bjursell M, Perez-Alcazar M, Seeliger F, Althage M, Knöll R, Hicks R, Mayr LM, Perkins R, Lindén D, Borén J, Bohlooly-Y M, Maresca M. Carreras A, et al. BMC Biol. 2019 Jan 15;17(1):4. doi: 10.1186/s12915-018-0624-2. BMC Biol. 2019. PMID: 30646909 Free PMC article.
2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.
Grundy SM, Stone NJ, Bailey AL, Beam C, Birtcher KK, Blumenthal RS, Braun LT, de Ferranti S, Faiella-Tommasino J, Forman DE, Goldberg R, Heidenreich PA, Hlatky MA, Jones DW, Lloyd-Jones D, Lopez-Pajares N, Ndumele CE, Orringer CE, Peralta CA, Saseen JJ, Smith SC Jr, Sperling L, Virani SS, Yeboah J. Grundy SM, et al. J Am Coll Cardiol. 2019 Jun 25;73(24):e285-e350. doi: 10.1016/j.jacc.2018.11.003. Epub 2018 Nov 10. J Am Coll Cardiol. 2019. PMID: 30423393 No abstract available.
Inhibiting PCSK9 - biology beyond LDL control.
Stoekenbroek RM, Lambert G, Cariou B, Hovingh GK. Stoekenbroek RM, et al. Nat Rev Endocrinol. 2018 Dec;15(1):52-62. doi: 10.1038/s41574-018-0110-5. Nat Rev Endocrinol. 2018. PMID: 30367179 Review.
Loss-of-function PCSK9 mutants evade the unfolded protein response sensor GRP78 and fail to induce endoplasmic reticulum stress when retained.
Lebeau P, Platko K, Al-Hashimi AA, Byun JH, Lhoták Š, Holzapfel N, Gyulay G, Igdoura SA, Cool DR, Trigatti B, Seidah NG, Austin RC. Lebeau P, et al. J Biol Chem. 2018 May 11;293(19):7329-7343. doi: 10.1074/jbc.RA117.001049. Epub 2018 Mar 28. J Biol Chem. 2018. PMID: 29593095 Free PMC article.
Inclisiran for the treatment of dyslipidemia.
Nishikido T, Ray KK. Nishikido T, et al. Expert Opin Investig Drugs. 2018 Mar;27(3):287-294. doi: 10.1080/13543784.2018.1442435. Epub 2018 Feb 22. Expert Opin Investig Drugs. 2018. PMID: 29451410 Review.
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