"PPAR alpha/antagonists and inhibitors"[MeSH] - Search Results

Year	Number of Results
2004	2
2005	6
2006	17
2007	12
2008	10
2009	16
2010	16
2011	20
2012	27
2013	19
2014	22
2015	22
2016	19
2017	18
2018	24
2019	12
2020	19
2021	11
2022	2
2024	0

1

Peroxisome proliferator-activated receptor agonists and antagonists: a patent review (2014-present).

Takada I, Makishima M. Takada I, et al. Expert Opin Ther Pat. 2020 Jan;30(1):1-13. doi: 10.1080/13543776.2020.1703952. Epub 2019 Dec 18. Expert Opin Ther Pat. 2020. PMID: 31825687 Review.

2

Silencing HIF-1α aggravates non-alcoholic fatty liver disease in vitro through inhibiting PPAR-α/ANGPTL4 singling pathway.

He Y, Yang W, Gan L, Liu S, Ni Q, Bi Y, Han T, Liu Q, Chen H, Hu Y, Long Y, Yang L. He Y, et al. Gastroenterol Hepatol. 2021 May;44(5):355-365. doi: 10.1016/j.gastrohep.2020.09.014. Epub 2020 Oct 23. Gastroenterol Hepatol. 2021. PMID: 33272734 English, Spanish.

3

Activated AMPK inhibits PPAR-{alpha} and PPAR-{gamma} transcriptional activity in hepatoma cells.

Sozio MS, Lu C, Zeng Y, Liangpunsakul S, Crabb DW. Sozio MS, et al. Am J Physiol Gastrointest Liver Physiol. 2011 Oct;301(4):G739-47. doi: 10.1152/ajpgi.00432.2010. Epub 2011 Jun 23. Am J Physiol Gastrointest Liver Physiol. 2011. PMID: 21700905 Free PMC article.

4

Targeting PPARalpha in Alzheimer's Disease.

D'Orio B, Fracassi A, Ceru MP, Moreno S. D'Orio B, et al. Curr Alzheimer Res. 2018 Feb 22;15(4):345-354. doi: 10.2174/1567205014666170505094549. Curr Alzheimer Res. 2018. PMID: 28474570 Review.

5

Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.

Lu X, Liu T, Chen K, Xia Y, Dai W, Xu S, Xu L, Wang F, Wu L, Li J, Li S, Wang W, Yu Q, Feng J, Fan X, Zhou Y, Niu P, Guo C. Lu X, et al. Biomed Pharmacother. 2018 Jul;103:800-811. doi: 10.1016/j.biopha.2018.04.016. Epub 2018 Apr 24. Biomed Pharmacother. 2018. PMID: 29684859

6

Selective PPARα Modulator Pemafibrate and Sodium-Glucose Cotransporter 2 Inhibitor Tofogliflozin Combination Treatment Improved Histopathology in Experimental Mice Model of Non-Alcoholic Steatohepatitis.

Murakami K, Sasaki Y, Asahiyama M, Yano W, Takizawa T, Kamiya W, Matsumura Y, Anai M, Osawa T, Fruchart JC, Fruchart-Najib J, Aburatani H, Sakai J, Kodama T, Tanaka T. Murakami K, et al. Cells. 2022 Feb 18;11(4):720. doi: 10.3390/cells11040720. Cells. 2022. PMID: 35203369 Free PMC article.

7

Antiepileptic action of N-palmitoylethanolamine through CB1 and PPAR-α receptor activation in a genetic model of absence epilepsy.

Citraro R, Russo E, Scicchitano F, van Rijn CM, Cosco D, Avagliano C, Russo R, D'Agostino G, Petrosino S, Guida F, Gatta L, van Luijtelaar G, Maione S, Di Marzo V, Calignano A, De Sarro G. Citraro R, et al. Neuropharmacology. 2013 Jun;69:115-26. doi: 10.1016/j.neuropharm.2012.11.017. Epub 2012 Dec 1. Neuropharmacology. 2013. PMID: 23206503

8

Citreoviridin induces triglyceride accumulation in hepatocytes through inhibiting PPAR-α in vivo and in vitro.

Feng C, Li D, Jiang L, Liu X, Li Q, Geng C, Sun X, Yang G, Yao X, Chen M. Feng C, et al. Chem Biol Interact. 2017 Aug 1;273:212-218. doi: 10.1016/j.cbi.2017.06.021. Epub 2017 Jun 21. Chem Biol Interact. 2017. PMID: 28645467

9

Discovery of potent and selective PPARα/δ dual antagonists and initial biological studies.

Jacintho JD, Baccei CS, Bravo Y, Broadhead A, Chen A, Correa L, Fischer K, Laffitte B, Lee C, Lorrain DS, Messmer D, Prasit P, Stebbins KJ, Stock NS. Jacintho JD, et al. Bioorg Med Chem Lett. 2019 Feb 1;29(3):503-508. doi: 10.1016/j.bmcl.2018.12.045. Epub 2018 Dec 21. Bioorg Med Chem Lett. 2019. PMID: 30594433

10

Sleep and neurochemical modulation by the nuclear peroxisome proliferator-activated receptor α (PPAR-α) in rat.

Mijangos-Moreno S, Poot-Aké A, Guzmán K, Arankowsky-Sandoval G, Arias-Carrión O, Zaldívar-Rae J, Sarro-Ramírez A, Murillo-Rodríguez E. Mijangos-Moreno S, et al. Neurosci Res. 2016 Apr;105:65-9. doi: 10.1016/j.neures.2015.09.005. Epub 2015 Oct 9. Neurosci Res. 2016. PMID: 26450400

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