Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

MyNCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 3
2004 145
2005 370
2006 390
2007 471
2008 513
2009 597
2010 660
2011 690
2012 748
2013 763
2014 728
2015 770
2016 726
2017 664
2018 643
2019 284
2020 8
Text availability
Article attribute
Article type
Publication date

Search Results

7,880 results
Results by year
Filters applied: . Clear all
Page 1
Fatty acids, eicosanoids and PPAR gamma.
Marion-Letellier R, et al. Eur J Pharmacol 2016 - Review. PMID 26632493
PPARγ have pleiotropic functions: (i) glucose and lipid metabolism regulation, (ii) anti-inflammatory properties, (iii) oxidative stress inhibition, (iv) improvement of endothelial function. ...
PPARγ have pleiotropic functions: (i) glucose and lipid metabolism regulation, (ii) anti-inflammatory properties, (iii) oxidative str …
The role of PPAR-gamma receptor in pruritus.
Ostadhadi S, et al. Eur J Pharmacol 2015 - Review. PMID 26057695
PPAR-γ agonists, thiazolidinediones, which are used in the treatment of diabetes mellitus, have been recently shown to diminish pruritus not only in animal models, but also in patients suffering from psoriasis; nevertheless, the role of PPAR-γ receptors in the pruritus is not well understood. In this perspective, a brief overview on the function of PPAR signaling in the pathogenesis of skin disorders as well as the involvement of PPAR-γ impact on pruritus is argued. ...
PPAR-γ agonists, thiazolidinediones, which are used in the treatment of diabetes mellitus, have been recently shown to diminish pruri
Peroxisome Proliferator-Activated Receptor-γ: Master Regulator of Adipogenesis and Obesity
Shao X, et al. Curr Stem Cell Res Ther 2016 - Review. PMID 26018229
PPAR includes three isoforms: PPAR-α, PPAR- β and PPAR- γ, all of which are exerting critical influences on the maintenance of the metabolism of saccharides, lipids and proteins. ...In this review, we focus on giving a brief introduction about PPAR family, the indispensible function of PPAR-γ in adipogenesis and the inseparable relationship between PPAR-γ and obesity, deriving from the understanding of how these receptors activated will provide windows of opportunities for the treatment of obesity and associated metabolism syndromes....
PPAR includes three isoforms: PPAR-α, PPAR- β and PPAR- γ, all of which are exerting critical influences on the
PPAR-γ and Wnt Regulate the Differentiation of MSCs into Adipocytes and Osteoblasts Respectively.
Li Y, et al. Curr Stem Cell Res Ther 2018 - Review. PMID 29034841
OBJECTIVE: In this review, we focus on the ties of PPAR-γ and Wnt signaling in MSC differentiation into adipocytes and osteoblasts. RESULTS: Peroxisome proliferator-activated receptor-γ (PPAR-γ) is well established as a prime inducer of adipogenesis, while the Wnt pathway is regarded as the master moderator of osteogenesis. ...
OBJECTIVE: In this review, we focus on the ties of PPAR-γ and Wnt signaling in MSC differentiation into adipocytes and osteoblasts. R …
Implications of the endogenous PPAR-gamma ligand, 15-deoxy-delta-12, 14-prostaglandin J2, in diabetic retinopathy.
Behl T, et al. Life Sci 2016 - Review. PMID 27060220
PPAR receptor, chiefly gamma subtype, mediates numerous responses related to glucose metabolism and hence is utilized, through its agonism, for the restoration of normal insulin sensitivity and glucose homeostasis in the body. ...Although the biological levels of 15d-PGJ2 (an endogenous agonist of PPAR-gamma receptor) are found to be below the concentration required to trigger PPAR-gamma-mediated actions, employment of several advanced methods for the exogenous administration of this ligand might provide a beneficial option. ...
PPAR receptor, chiefly gamma subtype, mediates numerous responses related to glucose metabolism and hence is utilized,
Senescence in hepatic stellate cells as a mechanism of liver fibrosis reversal: a putative synergy between retinoic acid and PPAR-gamma signalings.
Panebianco C, et al. Clin Exp Med 2017 - Review. PMID 27655446
The precise function of retinoic acid and its alterations in HSCs has yet to be elucidated, and nonetheless in various cell types retinoic acid and its receptors (RAR and RXR) are known to act synergistically with peroxisome proliferator-activated receptor gamma (PPAR-gamma) signaling through the activity of transcriptional heterodimers. Here, we review the recent advancements in the understanding of how retinoic acid signaling modulates the fibrogenic potential of HSCs and proposes a synergistic combined action with PPAR-gamma in the reversal of liver fibrosis....
The precise function of retinoic acid and its alterations in HSCs has yet to be elucidated, and nonetheless in various cell types retinoic a …
Interactions Between the Canonical WNT/Beta-Catenin Pathway and PPAR Gamma on Neuroinflammation, Demyelination, and Remyelination in Multiple Sclerosis.
Vallée A, et al. Cell Mol Neurobiol 2018 - Review. PMID 28905149
PPAR gamma activation can inhibit NF-kappaB, and can also downregulate the WNT/beta-catenin pathway. PPAR gamma and canonical WNT/beta-catenin pathway act in an opposite manner. PPAR gamma agonists appear as a promising treatment for the inhibition of demyelination and the promotion of proper remyelination through the control of both NF-kappaB activity and canonical WNT/beta-catenin pathway....
PPAR gamma activation can inhibit NF-kappaB, and can also downregulate the WNT/beta-catenin pathway. PPAR gamma
Nuclear Mechanisms of Insulin Resistance
Kang S, et al. Trends Cell Biol 2016 - Review. PMID 26822036 Free PMC article.
Mouse models of PPAR-gamma deficiency: dissecting PPAR-gamma's role in metabolic homoeostasis.
Gray SL, et al. Biochem Soc Trans 2005 - Review. PMID 16246044
These models exhibit phenotypes of partial PPAR-gamma impairment and are useful to elucidate how PPAR-gamma regulates specific metabolic processes. ...The mechanism involved in PPAR-gamma regulation of glucose homoeostasis is obscure as both agonism and partial impairment of PPAR-gamma increase insulin sensitivity. ...
These models exhibit phenotypes of partial PPAR-gamma impairment and are useful to elucidate how PPAR-gamma regu …
7,880 results
Jump to page
Feedback