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Year Number of Results
1979 1
1983 5
1984 14
1985 19
1986 11
1987 12
1988 10
1989 14
1990 11
1991 14
1992 10
1993 16
1994 7
1995 9
1996 10
1997 5
1998 7
1999 9
2000 13
2001 8
2002 7
2003 7
2004 10
2005 9
2006 4
2007 5
2008 6
2009 4
2010 4
2011 6
2012 2
2013 2
2014 1
2015 2
2016 2
2017 4
2020 0
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273 results
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Page 1
Preparation of cells from pig gastric mucosa. Isolation of parietal cells by isopycnic centrifugation on linear density gradients of Percoll.
Mårdh S, et al. Acta Physiol Scand 1984. Among authors: Carlsson C. PMID 6524398
Isolated mucosal cells attached to Petri dishes coated with fibronectin or collagen. Both parietal cells and chief cells adhered more readily to fibronectin than collagen. ...The accumulation of aminopyrine at 10(-6) M carbachol and 10(-7) M pentagastrin were for both secretagogues about 0.9 pmol per 10(4) parietal cells....
Isolated mucosal cells attached to Petri dishes coated with fibronectin or collagen. Both parietal cells
Dynamic functional and ultrastructural changes of gastric parietal cells induced by water immersion-restraint stress in rats.
Li YM, et al. World J Gastroenterol 2006. PMID 16733853 Free PMC article.
AIM: To investigate the dynamic functional and ultrastructural changes of gastric parietal cells induced by water immersion-restraint stress (WRS) in rats. ...In post-stress group, the parietal cells recovered to resting state. CONCLUSION: The acid secretion of parietal cells is consistent with their ultrastructural changes during the development and healing of stress ulcer induced by WRS and the degree of gastric mucosal lesions, suggesting gastric acid play an important role in the development of stress ulcer and is closely related with the recovery of gastric mucosal lesions induced by WRS....
AIM: To investigate the dynamic functional and ultrastructural changes of gastric parietal cells induced by water immer …
The unique ultrastructure of secretory membranes in gastric parietal cells depends upon the presence of H+, K+ -ATPase.
Miller ML, et al. Cell Tissue Res 2002. PMID 12195293
In H+, K+ -ATPase-deficient parietal cells, canalicular folds were decreased, normally abundant tubulovesicles were replaced with a few rigid round vesicles, and microvilli were sparse, stiff and short, in contrast to the long and flexible microvilli in wild-type cells. In addition, microvilli of the H+, K+ -ATPase-deficient parietal cells had centrally bundled F-actin filaments, unlike the microvilli of wild-type cells, in which actin filaments were peripherally positioned concentric to the plasmalemma. ...
In H+, K+ -ATPase-deficient parietal cells, canalicular folds were decreased, normally abundant tubulovesicles were rep …
Ultrastructural transformation of gastric parietal cells reverting from the active to the resting state of acid secretion revealed in isolated rat gastric mucosa model processed by high-pressure freezing.
Sawaguchi A, et al. J Electron Microsc (Tokyo) 2006. PMID 16702177
To elucidate a functional transformation of gastric parietal cells, we have newly developed an isolated rat gastric mucosa model whose parietal cells exhibited a reverting process from the active to the resting state of acid secretion. ...The present findings provide new insights into the functional transformation in gastric parietal cells reverting to their resting conformation....
To elucidate a functional transformation of gastric parietal cells, we have newly developed an isolated rat gastric mucosa mod …
A new approach for high-pressure freezing of primary culture cells: the fine structure and stimulation-associated transformation of cultured rabbit gastric parietal cells.
Sawaguchi A, et al. J Microsc 2002. PMID 12460447 Free article.
A newly designated procedure for high-pressure freezing of primary culture cells provided excellent ultrastructure of rabbit gastric parietal cells. The isolated parietal cells were cultivated on Matrigel-coated aluminium plates for conventional subsequential cryoimmobilization by high-pressure freezing. ...
A newly designated procedure for high-pressure freezing of primary culture cells provided excellent ultrastructure of rabbit g …
Cellular localization and stimulation-associated distribution dynamics of syntaxin-1 and syntaxin-3 in gastric parietal cells.
Karvar S, et al. Traffic 2005. Among authors: Crothers J. PMID 15998321 Free article.
We also examined the cellular localization of syntaxins in cultured parietal cells. Parietal cells were infected with CFP-syntaxin-1 and CFP-syntaxin-3 adenoviral constructs. ...In resting, non-secreting parietal cells, syntaxin-3 was distributed throughout the cytoplasmic compartment; after stimulation, syntaxin-3 translocated to the apical membrane vacuoles, there co-localizing with H,K-ATPase, syntaxin-1 and F-actin. ...
We also examined the cellular localization of syntaxins in cultured parietal cells. Parietal cells
Helicobacter pylori VacA disrupts apical membrane-cytoskeletal interactions in gastric parietal cells.
Wang F, et al. J Biol Chem 2008. Among authors: Cover TL. PMID 18625712 Free PMC article.
Here we show that VacA permeabilizes the apical membrane of gastric parietal cells and induces hypochlorhydria. The functional consequences of VacA infection on parietal cell physiology were studied using freshly isolated rabbit gastric glands and cultured parietal cells. ...Our results indicate that VacA disrupts the apical membrane-cytoskeletal interactions in gastric parietal cells and thereby causes hypochlorhydria....
Here we show that VacA permeabilizes the apical membrane of gastric parietal cells and induces hypochlorhydria. The functional …
The cryofixation of isolated rat gastric mucosa provides new insights into the functional transformation of gastric parietal cells: an in vitro experimental model study.
Sawaguchi A, et al. Arch Histol Cytol 2005. PMID 16276021 Free article.
In cimetidine-treated mucosa, most of the parietal cells were morphologically in the resting state, showing numerous tubulovesicles in their cytoplasm. In contrast, histamine-stimulated parietal cells exhibited well-developed intracellular canaliculi lined with long microvilli. ...
In cimetidine-treated mucosa, most of the parietal cells were morphologically in the resting state, showing numerous tu …
Exfoliation of gastric pit-parietal cells into the gastric lumen associated with a stimulation of isolated rat gastric mucosa in vitro: a morphological study by the application of cryotechniques.
Aoyama F, et al. Histochem Cell Biol 2008. PMID 18299880
As results, most of the exfoliated cells were identified as pit-parietal cells labeled with both peanut-lectin and anti-H+/K+-ATPase antibody. ...In addition, the pit-parietal cell exfoliation was accompanied by sealing of their basal portion with the cytoplasmic processes of adjacent surface mucous cells. ...
As results, most of the exfoliated cells were identified as pit-parietal cells labeled with both peanut-lectin and anti …
Functional transformation of gastric parietal cells and intracellular trafficking of ion channels/transporters in the apical canalicular membrane associated with acid secretion.
Aoyama F and Sawaguchi A. Biol Pharm Bull 2011 - Review. PMID 21628877 Free article.
The parietal cell of the gastric gland is a highly differentiated cell responsible for the gastric hydrochloric acid secretion into the lumen of the stomach. ...In the last decade, a number of molecular candidates for the Cl⁻ efflux and K⁺ recycling have been identified in the apical canalicular membrane of the parietal cell. ...
The parietal cell of the gastric gland is a highly differentiated cell responsible for the gastric hydrochloric acid se …
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