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Soluble guanylate cyclase signalling mediates etoposide resistance in progressing small cell lung cancer.
Schenk MW, Humphrey S, Hossain ASMM, Revill M, Pearsall S, Lallo A, Brown S, Bratt S, Galvin M, Descamps T, Zhou C, Pearce SP, Priest L, Greenhalgh M, Chaturvedi A, Kerr A, Blackhall F, Dive C, Frese KK. Schenk MW, et al. Among authors: pearsall s. Nat Commun. 2021 Nov 17;12(1):6652. doi: 10.1038/s41467-021-26823-6. Nat Commun. 2021. PMID: 34789728 Free PMC article.
Inhibiting activin-A signaling stimulates bone formation and prevents cancer-induced bone destruction in vivo.
Chantry AD, Heath D, Mulivor AW, Pearsall S, Baud'huin M, Coulton L, Evans H, Abdul N, Werner ED, Bouxsein ML, Key ML, Seehra J, Arnett TR, Vanderkerken K, Croucher P. Chantry AD, et al. Among authors: pearsall s. J Bone Miner Res. 2010 Dec;25(12):2633-46. doi: 10.1002/jbmr.142. Epub 2010 Jun 7. J Bone Miner Res. 2010. PMID: 20533325 Free article.
Differential muscle hypertrophy is associated with satellite cell numbers and Akt pathway activation following activin type IIB receptor inhibition in Mtm1 p.R69C mice.
Lawlor MW, Viola MG, Meng H, Edelstein RV, Liu F, Yan K, Luna EJ, Lerch-Gaggl A, Hoffmann RG, Pierson CR, Buj-Bello A, Lachey JL, Pearsall S, Yang L, Hillard CJ, Beggs AH. Lawlor MW, et al. Among authors: pearsall s. Am J Pathol. 2014 Jun;184(6):1831-42. doi: 10.1016/j.ajpath.2014.03.003. Epub 2014 Apr 13. Am J Pathol. 2014. PMID: 24726641 Free PMC article.
A soluble activin receptor type IIb prevents the effects of androgen deprivation on body composition and bone health.
Koncarevic A, Cornwall-Brady M, Pullen A, Davies M, Sako D, Liu J, Kumar R, Tomkinson K, Baker T, Umiker B, Monnell T, Grinberg AV, Liharska K, Underwood KW, Ucran JA, Howard E, Barberio J, Spaits M, Pearsall S, Seehra J, Lachey J. Koncarevic A, et al. Among authors: pearsall s. Endocrinology. 2010 Sep;151(9):4289-300. doi: 10.1210/en.2010-0134. Epub 2010 Jun 23. Endocrinology. 2010. PMID: 20573726