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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1982 7
1983 6
1984 6
1985 25
1986 21
1987 33
1988 40
1989 47
1990 50
1991 55
1992 50
1993 60
1994 47
1995 52
1996 50
1997 56
1998 55
1999 48
2000 49
2001 31
2002 35
2003 39
2004 66
2005 87
2006 92
2007 92
2008 95
2009 97
2010 96
2011 106
2012 106
2013 111
2014 112
2015 118
2016 107
2017 97
2018 71
2019 38
2020 0
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2,124 results
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Page 1
Bile acids drive colonic secretion of glucagon-like-peptide 1 and peptide-YY in rodents.
Christiansen CB, et al. Am J Physiol Gastrointest Liver Physiol 2019. PMID 30767682
A large number of glucagon-like-peptide-1 (GLP-1)- and peptide-YY (PYY)-producing L cells are located in the colon, but little is known about their contribution to whole body metabolism. ...NEW & NOTEWORTHY By the use of isolated perfused rodent colon preparations we show that bile acids are potent and direct promoters of colonic glucagon-like-peptide 1 and peptide-YY secretion. ...
A large number of glucagon-like-peptide-1 (GLP-1)- and peptide-YY (PYY)-producing L cells are located in the colon, but …
The Role of Neuropeptide Y and Peptide YY in the Development of Obesity via Gut-brain Axis.
Wu Y, et al. Curr Protein Pept Sci 2019 - Review. PMID 30678628
Both neuropeptide Y and peptide YY belong to the pancreatic polypeptide family and are important brain-gut peptides. Neuropeptide Y and peptide YY have functions that are closely related to appetite regulation and obesity formation. This review describes the role of the gutbrain axis in regulating appetite and maintaining energy balance, and the functions of brain-gut peptides neuropeptide Y and peptide YY in obesity. ...
Both neuropeptide Y and peptide YY belong to the pancreatic polypeptide family and are important brain-gut peptides. Neuropept …
Peptide YY: more than just an appetite regulator.
Persaud SJ and Bewick GA. Diabetologia 2014 - Review. PMID 24917132
We have recently identified a new role for the gut hormone peptide YY (PYY) and the neuropeptide Y (NPY) receptor systems in the control of beta cell survival. PYY is perhaps best known for its role in regulating appetite and body weight, but its production by islet cells, the presence of NPY receptors on islets and the demonstration that Y1 activation causes proliferation of beta cells and protects them from apoptosis, suggest a role for this peptide in modulating beta cell mass. ...
We have recently identified a new role for the gut hormone peptide YY (PYY) and the neuropeptide Y (NPY) receptor systems in t …
Emerging therapeutic potential for peptide YY for obesity-diabetes.
Lafferty RA, et al. Peptides 2018 - Review. PMID 29412828
The vast majority of research to date on the gut hormone Peptide YY (PYY) has focused on appetite suppression and body weight regulation effects. ...
The vast majority of research to date on the gut hormone Peptide YY (PYY) has focused on appetite suppression and body weight …
Expression of peptide YY by human blood leukocytes.
Holler JP, et al. Peptides 2014. PMID 24969624
We hypothesized that peptide YY is expressed by peripheral blood mononuclear cells. The purpose of the present study was to evaluate the expression of peptide YY mRNA and peptide by peripheral blood mononuclear cells and differentiated THP-1 cells after lipopolysaccharide treatment as an in vitro model of inflammation. ...In summary, freshly isolated peripheral blood mononuclear cells from healthy humans expressed peptide YY. In vitro data suggested that peptide YY expression is down-regulated by differentiation of monocytes to macrophages and proinflammatory stimuli....
We hypothesized that peptide YY is expressed by peripheral blood mononuclear cells. The purpose of the present study was to ev …
Timeline of changes in appetite during weight loss with a ketogenic diet
Nymo S, et al. Int J Obes (Lond) 2017. PMID 28439092 Free PMC article.
BACKGROUND/OBJECTIVE: Diet-induced weight loss (WL) leads to increased hunger and reduced fullness feelings, increased ghrelin and reduced satiety peptides concentration (glucagon-like peptide-1 (GLP-1), cholecystokinin (CCK) and peptide YY (PYY)). ...
BACKGROUND/OBJECTIVE: Diet-induced weight loss (WL) leads to increased hunger and reduced fullness feelings, increased ghrelin and reduced s …
Ghrelin, CCK, GLP-1, and PYY(3-36): Secretory Controls and Physiological Roles in Eating and Glycemia in Health, Obesity, and After RYGB
Steinert RE, et al. Physiol Rev 2017 - Review. PMID 28003328 Free PMC article.
Here we review the nutrient-sensing mechanisms that control the secretion of four of these hormones, ghrelin, cholecystokinin (CCK), glucagon-like peptide-1 (GLP-1), and peptide tyrosine tyrosine [PYY(3-36)], and their contributions to the controls of GI motor function, food intake, and meal-related increases in glycemia in healthy-weight and obese persons, as well as in RYGB patients. ...
Here we review the nutrient-sensing mechanisms that control the secretion of four of these hormones, ghrelin, cholecystokinin (CCK), glucago …
Peptide YY and glucagon-like peptide-1 contribute to decreased food intake after Roux-en-Y gastric bypass surgery.
Svane MS, et al. Int J Obes (Lond) 2016 - Clinical Trial. PMID 27434221
BACKGROUND/OBJECTIVES: Exaggerated postprandial secretion of glucagon-like peptide-1 (GLP-1) and peptide YY (PYY) may explain appetite reduction and weight loss after Roux-en-Y gastric bypass (RYGB), but causality has not been established. ...
BACKGROUND/OBJECTIVES: Exaggerated postprandial secretion of glucagon-like peptide-1 (GLP-1) and peptide YY (PYY) may e …
Ghrelin and Peptide YY Change During Puberty: Relationships With Adolescent Growth, Development, and Obesity.
Cheng HL, et al. J Clin Endocrinol Metab 2018. PMID 29860506
How this is mediated is unclear, but ghrelin and peptide YY (PYY) play potentially important roles. OBJECTIVE: To measure ghrelin and PYY change in relation to pubertal growth. ...
How this is mediated is unclear, but ghrelin and peptide YY (PYY) play potentially important roles. OBJECTIVE: To measure ghre …
Bidirectional GPR119 Agonism Requires Peptide YY and Glucose for Activity in Mouse and Human Colon Mucosa.
Tough IR, et al. Endocrinology 2018. PMID 29471473 Free PMC article.
The lipid sensor G protein-coupled receptor 119 (GPR119) is highly expressed by enteroendocrine L-cells and pancreatic β-cells that release the hormones, peptide YY (PYY) and glucagonlike peptide 1, and insulin, respectively. ...
The lipid sensor G protein-coupled receptor 119 (GPR119) is highly expressed by enteroendocrine L-cells and pancreatic β-cells that release …
2,124 results
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