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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 2
1994 4
1995 4
1996 4
1997 10
1998 12
1999 6
2000 8
2001 12
2002 11
2003 7
2004 11
2005 10
2006 6
2007 10
2008 13
2009 14
2010 15
2011 11
2012 19
2013 19
2014 12
2015 20
2016 12
2017 5
2018 3
2019 1
2020 0
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231 results
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Page 1
The effect of statins on periodontal treatment-a systematic review with meta-analyses and meta-regression.
Muniz FWMG, et al. Clin Oral Investig 2018 - Review. PMID 29396642
OBJECTIVE: This study aimed to systematically review clinical trials about the effect of statins as adjunct to mechanical periodontal therapy, on probing pocket depth, clinical attachment level, and intrabony defects, in comparison to mechanical periodontal therapy alone or in association with placebo. ...Weighted mean differences between baseline and 6 months after periodontal treatment for clinical attachment level (CAL), probing pocket depth (PPD), and intrabony defect (IBD) were calculated. ...
OBJECTIVE: This study aimed to systematically review clinical trials about the effect of statins as adjunct to mechanical periodontal
The effect of local and systemic statin use as an adjunct to non-surgical and surgical periodontal therapy-A systematic review and meta-analysis.
Bertl K, et al. J Dent 2017 - Review. PMID 28855141
OBJECTIVES: To evaluate the effect of local and/or systemic statin use as an adjunct to non-surgical and/or surgical periodontal therapy. ...Local but not systemic statin application as an adjunct to SRP yielded significantly larger probing pocket depth (PD), radiographic defect depth (RDD), and bleeding index reduction, and larger clinical attachment level gain, and less residual PD and RDD (p≤0.016); rosuvastatin appeared as the most efficacious. ...
OBJECTIVES: To evaluate the effect of local and/or systemic statin use as an adjunct to non-surgical and/or surgical periodontal t
Systemic antibiotics in the treatment of aggressive periodontitis. A systematic review and a Bayesian Network meta-analysis
Rabelo CC, et al. J Clin Periodontol 2015 - Review. PMID 26087839
AIM: The aim of this study was to assess the effect of systemic antibiotic therapy on the treatment of aggressive periodontitis (AgP). ...Greater gain in clinical attachment (CA) (mean difference [MD]: 1.08 mm; p < 0.0001) and reduction in probing depth (PD) (MD: 1.05 mm; p < 0.00001) were observed for SRP + metronidazole (Mtz), and for SRP + Mtz + amoxicillin (Amx) (MD: 0.45 mm, MD: 0.53 mm, respectively; p < 0.00001) than SRP alone/placebo. ...
AIM: The aim of this study was to assess the effect of systemic antibiotic therapy on the treatment of aggressive periodontitis (AgP) …
Systemic antimicrobials adjuvant to periodontal therapy in diabetic subjects: a meta-analysis.
Grellmann AP, et al. J Clin Periodontol 2016 - Review. PMID 26790108
BACKGROUND: Adjuvant antibiotics have been suggested to improve periodontal therapy in diabetic subjects. AIM: The aim of this study was to systematically review randomized clinical trials assessing systemic antimicrobial use adjuvant to scaling and root planing (SRP) versus SRP alone in diabetic subjects. ...CONCLUSION: Adjunctive therapy may improve the efficacy of SRP in reducing PD in diabetic subjects....
BACKGROUND: Adjuvant antibiotics have been suggested to improve periodontal therapy in diabetic subjects. AIM: The aim of this …
Two-Year Randomized Clinical Trial of Adjunctive Minocycline Microspheres in Periodontal Maintenance.
Killeen AC, et al. J Dent Hyg 2018 - Clinical Trial. PMID 30143550
Baseline and 24-month measurements included radiographic interproximal alveolar bone height, probing depths (PD), clinical attachment level (CAL), bleeding on probing (BOP), gingival crevicular fluid (GCF), and salivary interleukin (IL) - 1β, (24 month only). ...However, there were no differences between groups over the 24-month study period.Conclusion: Scaling and root planning alone, of moderately inflamed periodontal pockets at 6-month intervals, produced stable interproximal alveolar bone height as well as sustained improvements in probing depths, clinical attachment level, bleeding on probing over 24 months; minocycline microspheres were not shown to enhance these results....
Baseline and 24-month measurements included radiographic interproximal alveolar bone height, probing depths (PD), clinical attachment
Maintenance periodontal therapy after systemic antibiotic and regenerative therapy of generalized aggressive periodontitis. A case report with 10-year follow-up.
Siqueira SJ, et al. Dent Update 2015. PMID 26062264
Aggressive periodontitis (AgP) is an inflammatory disease characterized by rapid attachment loss and bone destruction. This case report presents the 10-year results in a subject with generalized AgP treated by a regenerative periodontal therapeutic approach and the adjunctive use of antibiotics, following a systematic maintenance periodontal therapy. ...Clinical Relevance: The combined treatment protocol using EMD plus adjunctive antibiotic therapy, associated with a systematic supportive periodontal therapy, benefits the long-term maintenance of teeth with previous advanced periodontal defects in subjects presenting AgP, supporting this approach as an alternative in the treatment of AgP....
Aggressive periodontitis (AgP) is an inflammatory disease characterized by rapid attachment loss and bone destruction. This ca …
Enamel matrix derivative (Emdogain) for periodontal tissue regeneration in intrabony defects. A Cochrane systematic review.
Esposito M, et al. Eur J Oral Implantol 2009 - Review. PMID 20467602
Amelogenins are involved in the formation of enamel and periodontal attachment formation during tooth development. OBJECTIVES: To test whether EMD is effective, and to compare EMD versus GTR, and various BG procedures for the treatment of intrabony defects. ...The outcome measures considered were: tooth loss, changes in probing attachment levels (PAL), pocket depths (PPD), gingival recessions (REC), bone levels from the bottom of the defects on intraoral radiographs, aesthetics and adverse events. ...
Amelogenins are involved in the formation of enamel and periodontal attachment formation during tooth development. OBJECTIVES: …
Scaling and Root Planing per Quadrant Versus One-Stage Full-Mouth Disinfection: Assessment of the Impact of Chronic Periodontitis Treatment on Quality of Life--A Clinical Randomized, Controlled Trial
Santuchi CC, et al. J Periodontol 2016 - Clinical Trial. PMID 26376944
This study aims to compare the effects of two different forms of non-surgical periodontal therapy, scaling and root planing (SRP) per quadrant and one-stage full-mouth disinfection (FMD), on periodontal clinical parameters and OHRQL of patients with chronic periodontitis. ...Periodontal clinical parameters recorded included probing depth, clinical attachment level, plaque index, and gingival index. ...
This study aims to compare the effects of two different forms of non-surgical periodontal therapy, scaling and root planing (S …
Effect of systemic long-term, low-dose aspirin on periodontal status and soluble CD14 in gingival crevicular fluid: a case-control study.
Bali SK, et al. J Investig Clin Dent 2018. PMID 30062853
METHODS: The study group consisted of 45 patients who were on long-term, low-dose aspirin therapy, and the control group included patients not on aspirin therapy. Mean bleeding index, plaque index (PI), probing depth (PD), and clinical attachment loss (CAL) were recorded. GCF samples were analyzed for concentrations of ATL, and sCD14 using enzyme-linked immunosorbent assay method. ...
METHODS: The study group consisted of 45 patients who were on long-term, low-dose aspirin therapy, and the control group included pat …
Treatment of subjects with refractory periodontal disease.
Magnusson I, et al. J Clin Periodontol 1994 - Clinical Trial. PMID 7806681
The remainder of sites showed no change between pre- and post-therapy monitoring periods. The progression of attachment loss in the active sites could not be completely stopped over the entire 2-year period. After 12-15 months following therapy, there was a tendency towards new loss of attachment and an increase of pocket depth. However, all 4 subjects treated with placebo drug demonstrated continuous deterioration and had to be retreated. ...
The remainder of sites showed no change between pre- and post-therapy monitoring periods. The progression of attachment los
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