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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1972 4
1973 4
1974 10
1975 7
1976 6
1977 7
1978 6
1979 4
1980 6
1981 7
1982 3
1983 10
1984 5
1985 8
1986 10
1987 7
1988 7
1989 18
1990 18
1991 25
1992 18
1993 15
1994 15
1995 20
1996 19
1997 16
1998 19
1999 10
2000 19
2001 31
2002 28
2003 22
2004 22
2005 16
2006 24
2007 14
2008 38
2009 44
2010 45
2011 42
2012 60
2013 37
2014 51
2015 23
2016 32
2017 45
2018 29
2019 10
2020 0
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854 results
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Page 1
Treatment of periodontal intrabony defects using autologous periodontal ligament stem cells: a randomized clinical trial.
Chen FM, et al. Stem Cell Res Ther 2016 - Clinical Trial. PMID 26895633 Free PMC article.
Evidence from preclinical trials and small-scale pilot clinical studies indicates that stem cells derived from periodontal ligament tissues are a promising therapy for the regeneration of lost/damaged periodontal tissue. This study assessed the safety and feasibility of using autologous periodontal ligament stem cells (PDLSCs) as an adjuvant to grafting materials in guided tissue regeneration (GTR) to treat periodontal intrabony defects. ...
Evidence from preclinical trials and small-scale pilot clinical studies indicates that stem cells derived from periodontal ligament t …
The Fate of Transplanted Periodontal Ligament Stem Cells in Surgically Created Periodontal Defects in Rats.
Iwasaki K, et al. Int J Mol Sci 2019. PMID 30621073 Free PMC article.
Human periodontal ligament stem cells (PDLSCs) were transferred to decellularized amniotic membrane and transplanted into periodontal defects in rats. ...This study describes a novel stem cell transplantation strategy for periodontal disease using the cell transfer technology and offers new insight for cell-based periodontal regeneration....
Human periodontal ligament stem cells (PDLSCs) were transferred to decellularized amniotic membrane and transplanted into periodon
Chemokine in inflamed periodontal tissues activates healthy periodontal-ligament stem cell migration.
Lee JS, et al. J Clin Periodontol 2017. PMID 28207939
AIM: The present study aimed to characterize the expression pattern of chemokines obtained from inflamed periodontal defects and to determine the characteristics of human periodontal-ligament stem cells (hPDLSCs) migrated by each specific chemokine. ...CONCLUSION: The present study found a specific chemokine profile induced by inflammation in periodontal tissues, with RANTES/CCL5 appearing to play a role in the migration of hPDLSCs into inflammatory periodontal lesions....
AIM: The present study aimed to characterize the expression pattern of chemokines obtained from inflamed periodontal defects and to d …
Cytotoxicity of Self-Adhesive Resin Cements on Human Periodontal Ligament Fibroblasts.
Sun F, et al. Biomed Res Int 2018. PMID 30627569 Free PMC article.
The aim of this study was to evaluate the potential cytotoxicity of self-adhesive resin cements with or without light irradiation on human periodontal ligament fibroblasts (HPDLFs) in vitro. ...
The aim of this study was to evaluate the potential cytotoxicity of self-adhesive resin cements with or without light irradiation on human …
Effects of loss of occlusal contact on the expression of matrix metalloproteinase-2, membrane type 1-MMP, tissue inhibitor of the MMP-2, eruption rate, organization and resistance of collagen fibers of the rat incisor periodontal ligament.
Omar NF, et al. J Periodontal Res 2018. PMID 29044524
Collagen protein organization, as indicated by the birefringence of the periodontal ligament, was analyzed under polarized light and the periodontal ligament's resistance was determined from the load necessary to inject the incisor into its alveolar space, before extraction. RESULTS: Loss of occlusal contact, in rats submitted to hypofunctional eruption, increased MMP-2 activity and eruption rate, but decreased MT1-MMP and TIMP-2 expression and disrupted collagen organization in the periodontal ligament, consequently reducing periodontal ligament resistance. ...
Collagen protein organization, as indicated by the birefringence of the periodontal ligament, was analyzed under polarized light and …
Porphyromonas gingivalis can invade periodontal ligament stem cells.
Pan C, et al. BMC Microbiol 2017. PMID 28212613 Free PMC article.
Periodontal ligament stem cells (PDLSCs) play an important role in the maintenance of periodontal tissue self-renewal and repair. ...
Periodontal ligament stem cells (PDLSCs) play an important role in the maintenance of periodontal tissue self-renewal and repa
Investigation of periodontal ligament reaction upon excessive occlusal load--osteopontin induction among periodontal ligament cells.
Kaku M, et al. J Periodontal Res 2005. PMID 15613081
The destruction of the periodontal ligament was observed and the production of osteopontin and RANKL by periodontal ligament cells was detected via immunohistochemistry. RESULTS: Our model produced wide-ranging destruction of the periodontal ligament. From day 3 to day 7, prominent compression of the periodontal ligament and osteoclast migration were observed at the apical interradicular septum. ...
The destruction of the periodontal ligament was observed and the production of osteopontin and RANKL by periodontal ligament c …
Human periodontal ligament cell sheets can regenerate periodontal ligament tissue in an athymic rat model.
Hasegawa M, et al. Tissue Eng 2005. PMID 15869425
Conventional periodontal regeneration methods remain insufficient to attain complete and reliable clinical regeneration of periodontal tissues. ...The purpose of this study was to investigate the characteristics of human periodontal ligament (HPDL) cell sheets retrieved from culture on unique temperature-responsive culture dishes, and to examine whether these cell sheets can regenerate periodontal tissues. ...
Conventional periodontal regeneration methods remain insufficient to attain complete and reliable clinical regeneration of periodo
854 results
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