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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 1
1965 12
1966 29
1967 20
1968 31
1969 13
1970 16
1971 14
1972 17
1973 22
1974 23
1975 15
1976 14
1977 14
1978 24
1979 16
1980 13
1981 26
1982 15
1983 22
1984 56
1985 44
1986 36
1987 44
1988 41
1989 48
1990 56
1991 47
1992 53
1993 56
1994 54
1995 48
1996 63
1997 49
1998 80
1999 54
2000 58
2001 59
2002 76
2003 52
2004 78
2005 84
2006 81
2007 71
2008 86
2009 77
2010 103
2011 100
2012 115
2013 124
2014 117
2015 140
2016 150
2017 144
2018 125
2019 85
2020 3
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2,892 results
Results by year
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Page 1
[Statins in periodontitis therapy].
Li SS, et al. Zhonghua Kou Qiang Yi Xue Za Zhi 2017 - Review. PMID 28253583 Chinese.
Studies have found that statins also play a positive role in periodontitis treatment. In this paper, we reviewed the functions of statins in bone metabolism and anti-inflammation in periodontitis. In addition, the application of statins as a local drug delivery system in the treatment of periodontitis was described....
Studies have found that statins also play a positive role in periodontitis treatment. In this paper, we reviewed the functions of sta …
Antibiotics/antimicrobials: systemic and local administration in the therapy of mild to moderately advanced periodontitis.
Jepsen K and Jepsen S. Periodontol 2000 2016 - Review. PMID 27045432
In particular, it addresses whether their use can improve the results of nonsurgical mechanical therapy in mild-to-moderate forms of the disease. ...These effects are more pronounced in aggressive periodontitis and in initially deep pockets, whereas more limited additional improvements, of 0.3 mm for additional pocket reduction and 0.2 mm for additional clinical attachment gain, have been documented for moderately deep sites (4-6 mm) in patients with chronic periodontitis. ...
In particular, it addresses whether their use can improve the results of nonsurgical mechanical therapy in mild-to-moderate forms of …
Advanced drug delivery approaches against periodontitis.
Joshi D, et al. Drug Deliv 2016 - Review. PMID 25005586
Various local or systemic approaches were used for an effective treatment of periodontitis. Currently, controlled local drug delivery approach is more favorable as compared to systemic approach because it mainly focuses on improving the therapeutic outcomes by achieving factors like site-specific delivery, low dose requirement, bypass of first-pass metabolism, reduction in gastrointestinal side effects and decrease in dosing frequency. ...The review summarizes various available and recently developing targeted delivery devices for the treatment of periodontitis....
Various local or systemic approaches were used for an effective treatment of periodontitis. Currently, controlled local drug d …
Systemic antibiotics in the treatment of periodontitis.
Feres M, et al. Periodontol 2000 2015 - Review. PMID 25494600
Basic questions concerning the use of systemic antibiotics to treat periodontitis remain unanswered, such as: which drug(s) should be used; which patients would most benefit from treatment; which are the most effective protocols (i.e. doses and durations); and in which phase of the mechanical therapy should the drug(s) be administered? ...This article endeavored to provide a 'state of the art' overview on the use of systemic antibiotics in the treatment of periodontitis, based on the most recent literature on the topic as well as on a compilation of data from studies conducted at the Center of Clinical Trials at Guarulhos University (São Paulo, Brazil) from 2002 to 2012....
Basic questions concerning the use of systemic antibiotics to treat periodontitis remain unanswered, such as: which drug(s) sh …
Local Drug Delivery Systems in the Treatment of Periodontitis: A Literature Review.
Da Rocha HA, et al. J Int Acad Periodontol 2015 - Review. PMID 26373225
In order to complement non-surgical therapy in periodontitis, there are multiple options of antimicrobials, such as metronidazole, chlorhexidine, minocycline, doxycycline and tetracycline, which can be locally delivered into the mucosa. ...Furthermore, local drug delivery as an active treatment or maintenance therapy depends on clinical findings, responses to treatment described in the literature, desired clinical outcomes, and patients' dental and medical histories, including their past usage of antimicrobials....
In order to complement non-surgical therapy in periodontitis, there are multiple options of antimicrobials, such as metronidaz …
Efficacy of photodynamic therapy as adjunct treatment of chronic periodontitis: a systematic review and meta-analysis.
Azaripour A, et al. Lasers Med Sci 2018 - Review. PMID 29177555
Meta-analysis of treatment effects of antimicrobial photodynamic therapy (aPDT) adjunct to non-surgical scaling and root planing (SRP) in comparison to SRP alone on patients with chronic periodontitis. ...Sensitivity analysis minimized heterogeneity of PD reduction (MD 0.21; 95% CI 0.13-0.30; P < 0.00001) and CAL gain (MD 0.36; 95% CI 0.27-0.46). aPDT adjunct to SRP provides significant PD reduction and CAL gain in treatment of chronic periodontitis. ...
Meta-analysis of treatment effects of antimicrobial photodynamic therapy (aPDT) adjunct to non-surgical scaling and root planing (SRP …
Host modulation therapy using anti-inflammatory and antioxidant agents in periodontitis: A review to a clinical translation.
Sulijaya B, et al. Arch Oral Biol 2019 - Review. PMID 31288144
OBJECTIVE: To highlight the shifting paradigm of periodontitis, describe mechanism of periodontal bone destruction, and propose an updated host modulation therapy (HMT) strategy. ...DESIGN: Literature searches were conducted from articles published in PubMed using keywords "periodontal disease AND periodontitis AND host modulation therapy AND anti-inflammatory AND antioxidant", and then the findings were comprehensively summarized and elaborated. ...
OBJECTIVE: To highlight the shifting paradigm of periodontitis, describe mechanism of periodontal bone destruction, and propose an up …
Hyaluronic acid: Perspectives in dentistry. A systematic review
Casale M, et al. Int J Immunopathol Pharmacol 2016 - Review. PMID 27280412 Free PMC article.
At the end of our study selection process, 25 relevant publications were included, three of them regarding gingivitis, 13 of them relating to chronic periodontitis, seven of them relating to dental surgery, including implant and sinus lift procedures, and the remaining three articles describing oral ulcers. ...
At the end of our study selection process, 25 relevant publications were included, three of them regarding gingivitis, 13 of them relating t …
Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults.
Cope AL, et al. Cochrane Database Syst Rev 2018 - Review. PMID 30259968 Free PMC article.
Symptomatic apical periodontitis and acute apical abscess are common causes of dental pain and arise from an inflamed or necrotic dental pulp, or infection of the pulpless root canal system. ...The body of evidence was assessed as at very low quality.Objective 2: systemic antibiotics without surgical intervention for adults with symptomatic apical periodontitis or acute apical abscessWe found no studies that compared the effects of systemic antibiotics with a matched placebo delivered without a surgical intervention for symptomatic apical periodontitis or acute apical abscess in adults. ...
Symptomatic apical periodontitis and acute apical abscess are common causes of dental pain and arise from an inflamed or necrotic den …
The anti-inflammatory effect of locally delivered nano-doxycycline gel in therapy of chronic periodontitis.
Madi M, et al. Acta Odontol Scand 2018. PMID 28959907
BACKGROUND AND OBJECTIVE: To date, various drugs as host modulating agents had been suggested as adjunctive treatment modality in the therapy of chronic periodontal disease. ...Plaque Index (PI), Gingival Index (GI), pocket depth (PD) and clinical attachment level(CAL), as well as ginigival crevicular fluid levels of (GCF) IL-6 and TNF-α were assessed at baseline, 1 and 3 months following local drug application. ...
BACKGROUND AND OBJECTIVE: To date, various drugs as host modulating agents had been suggested as adjunctive treatment modality in the the
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