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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 1
1972 2
1973 3
1974 27
1975 50
1976 27
1977 31
1978 23
1979 25
1980 33
1981 31
1982 35
1983 36
1984 54
1985 45
1986 72
1987 49
1988 50
1989 67
1990 80
1991 78
1992 82
1993 86
1994 79
1995 83
1996 89
1997 106
1998 130
1999 136
2000 168
2001 171
2002 157
2003 138
2004 152
2005 160
2006 169
2007 184
2008 186
2009 186
2010 188
2011 202
2012 204
2013 209
2014 174
2015 203
2016 199
2017 188
2018 160
2019 64
2020 2
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4,694 results
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Page 1
Necroptotic cell death in anti-cancer therapy
Krysko O, et al. Immunol Rev 2017 - Review. PMID 29027225
Next, we discuss the molecular mechanisms of phosphatidylserine exposure during necroptosis and its role in the recognition of necroptotic cells. ...
Next, we discuss the molecular mechanisms of phosphatidylserine exposure during necroptosis and its role in the recognition of necrop …
Phosphatidylserine in the brain: metabolism and function.
Kim HY, et al. Prog Lipid Res 2014 - Review. PMID 24992464 Free PMC article.
Phosphatidylserine (PS) is the major anionic phospholipid class particularly enriched in the inner leaflet of the plasma membrane in neural tissues. PS is synthesized from phosphatidylcholine or phosphatidylethanolamine by exchanging the base head group with serine, and this reaction is catalyzed by phosphatidylserine synthase 1 and phosphatidylserine synthase 2 located in the endoplasmic reticulum. ...
Phosphatidylserine (PS) is the major anionic phospholipid class particularly enriched in the inner leaflet of the plasma membrane in
An Apoptotic 'Eat Me' Signal: Phosphatidylserine Exposure.
Segawa K and Nagata S. Trends Cell Biol 2015 - Review. PMID 26437594
For apoptotic cells to be cleared, they must display an 'eat me' signal, most likely phosphatidylserine (PtdSer) exposure, which prompts phagocytes to engulf the cells. ...
For apoptotic cells to be cleared, they must display an 'eat me' signal, most likely phosphatidylserine (PtdSer) exposure, which prom …
The diversity of platelet microparticles
Boilard E, et al. Curr Opin Hematol 2015 - Review. PMID 26214207
Platelet microparticles are commonly characterized by the expression of surface platelet antigens and phosphatidylserine. In fact, only a fraction of platelet microparticles harbor phosphatidylserine, and a distinct subset contains respiratory-competent mitochondria. ...
Platelet microparticles are commonly characterized by the expression of surface platelet antigens and phosphatidylserine. In fact, on …
Viral apoptotic mimicry
Amara A and Mercer J. Nat Rev Microbiol 2015 - Review. PMID 26052667
Viral apoptotic mimicry, defined by the exposure of phosphatidylserine - a marker for apoptosis - on the pathogen surface, is emerging as a common theme used by enveloped viruses to promote infection. ...
Viral apoptotic mimicry, defined by the exposure of phosphatidylserine - a marker for apoptosis - on the pathogen surface, is emergin …
Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer.
Birge RB, et al. Cell Death Differ 2016 - Review. PMID 26915293 Free PMC article.
It serves important roles in physiology by sculpting complex tissues during embryogenesis and by removing effete cells that have reached advanced age or whose genomes have been irreparably damaged. ...The externalization of phosphatidylserine (PS) is arguably the most emblematic eat-me signal that is in turn bound by a large number of serum proteins and opsonins that facilitate efferocytosis. ...
It serves important roles in physiology by sculpting complex tissues during embryogenesis and by removing effete cells that have reac …
Getting to the Outer Leaflet: Physiology of Phosphatidylserine Exposure at the Plasma Membrane.
Bevers EM and Williamson PL. Physiol Rev 2016 - Review. PMID 26936867 Free article.
Phosphatidylserine (PS) is a major component of membrane bilayers whose change in distribution between inner and outer leaflets is an important physiological signal. ...
Phosphatidylserine (PS) is a major component of membrane bilayers whose change in distribution between inner and outer leaflets is an
Living Neurons with Tau Filaments Aberrantly Expose Phosphatidylserine and Are Phagocytosed by Microglia.
Brelstaff J, et al. Cell Rep 2018. PMID 30134156 Free PMC article.
We report that living neurons with tau inclusions from P301S-tau mice expose abnormally high amounts of phosphatidylserine because of the production of reactive oxygen species (ROS). ...
We report that living neurons with tau inclusions from P301S-tau mice expose abnormally high amounts of phosphatidylserine because of …
Phosphatidylserine.
Pepping J. Am J Health Syst Pharm 1999 - Review. PMID 10541030
Cell-surface phosphatidylserine regulates osteoclast precursor fusion.
Verma SK, et al. J Biol Chem 2018. PMID 29101233 Free PMC article.
We found that osteoclast fusion required the dendrocyte-expressed seven transmembrane protein (DC-STAMP)-dependent non-apoptotic exposure of phosphatidylserine at the surface of fusion-committed cells. Fusion also depended on extracellular annexins, phosphatidylserine-binding proteins, which, along with annexin-binding protein S100A4, regulated fusogenic activity of syncytin 1. ...
We found that osteoclast fusion required the dendrocyte-expressed seven transmembrane protein (DC-STAMP)-dependent non-apoptotic exposure of …
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