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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1983 1
1987 1
1988 1
1989 5
1990 7
1991 6
1992 5
1993 7
1994 7
1995 24
1996 43
1997 44
1998 69
1999 56
2000 80
2001 63
2002 65
2003 100
2004 112
2005 97
2006 120
2007 112
2008 181
2009 212
2010 250
2011 267
2012 247
2013 267
2014 279
2015 361
2016 325
2017 279
2018 283
2019 116
2020 1
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3,663 results
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Page 1
Evaluating the Effect of Six Proton Pump Inhibitors on the Antiplatelet Effects of Clopidogrel.
Przespolewski ER, et al. J Stroke Cerebrovasc Dis 2018 - Clinical Trial. PMID 29449127
Participants underwent platelet aggregation testing after clopidogrel alone, while on clopidogrel in combination with 1 of 3 PPIs (40 mg of pantoprazole, 20 mg of omeprazole, 20 mg of rabeprazole, 40 mg of esomeprazole, 30 mg of lansoprazole, or 30 mg of dexlansoprazole), and during 1 week of clopidogrel-only washout periods. FINDINGS: The median platelet aggregation to adenosine diphosphate during a drug-free baseline was 10Ω (2.5 interquartile range) of impedance and decreased to 0Ω on clopidogrel alone. ...
Participants underwent platelet aggregation testing after clopidogrel alone, while on clopidogrel in combination with 1 of 3 P …
Oral Administration of Sustained Release Niacin Inhibits Platelet Aggregation.
Norgard NB, et al. Curr Clin Pharmacol 2016. PMID 26651612
OBJECTIVE: The purpose of this trial was to investigate whether the oral administration of niacin inhibits platelet aggregation. ...Significant inhibition of platelet aggregation was found one hour following the oral administration of 1 gram of SR niacin while the oral administration of a 2 gram dose of SR niacin did not produce significant platelet inhibition when platelet aggregation was measured 12 hours after the dose. ...
OBJECTIVE: The purpose of this trial was to investigate whether the oral administration of niacin inhibits platelet aggrega
Semi-mechanistic modelling and simulation of inhibition of platelet aggregation by antiplatelet agents.
Yun HY, et al. Basic Clin Pharmacol Toxicol 2014. PMID 24612881 Free article.
Antiplatelet agents are a class of pharmaceuticals that decrease platelet aggregation and thus inhibit thrombus formation. We examined the relationships between plasma concentrations of antiplatelet agents (triflusal, clopidogrel and cilostazol) and the platelet aggregation inhibitory effect after dosing. ...In addition, the estimated parameters were suitable for the explanation of the agents and also have a good correlation with platelet characteristics, such as platelet half-life and platelet aggregation baseline effects. ...
Antiplatelet agents are a class of pharmaceuticals that decrease platelet aggregation and thus inhibit thrombus formation. We …
Cangrelor in Percutaneous Coronary Intervention: Current Status and Perspectives
Alexopoulos D, et al. J Cardiovasc Pharmacol Ther 2018 - Review. PMID 29228817
Nevertheless, the clinical role of cangrelor in conjunction with administration of prasugrel or ticagrelor remains unclear. Accruing real-life experience is expected to improve our understanding of cangrelor's role in everyday clinical practice....
Nevertheless, the clinical role of cangrelor in conjunction with administration of prasugrel or ticagrelor remains unclear. Accruing …
The Role of Chemoprophylactic Agents in Modulating Platelet Aggregability After Traumatic Brain Injury.
Morris MC, et al. J Surg Res 2019. PMID 31279258 Free PMC article.
We hypothesized that utilization of aspirin, ketorolac, amitriptyline, unfractionated heparin, or enoxaparin would modulate the platelet aggregation response after TBI. ...By contrast, adenosine diphosphate- and arachidonic acid-induced platelet aggregation at 6 h was significantly lower in mice receiving ketorolac, aspirin, and amitriptyline compared with mice receiving saline at 6 h after injury and only arachidonic acid-initiated platelet aggregation was decreased by aspirin at 24 h. ...
We hypothesized that utilization of aspirin, ketorolac, amitriptyline, unfractionated heparin, or enoxaparin would modulate the platelet
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