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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1974 1
1975 6
1976 1
1977 8
1978 7
1979 7
1980 8
1981 8
1982 14
1983 9
1984 17
1985 14
1986 22
1987 13
1988 13
1989 14
1990 18
1991 16
1992 23
1993 28
1994 21
1995 20
1996 28
1997 20
1998 17
1999 32
2000 30
2001 19
2002 23
2003 36
2004 52
2005 52
2006 80
2007 78
2008 95
2009 114
2010 122
2011 139
2012 151
2013 115
2014 125
2015 101
2016 101
2017 93
2018 80
2019 42
2020 2
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1,826 results
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Page 1
Immediate-type hypersensitivity to polyethylene glycols: a review.
Wenande E and Garvey LH. Clin Exp Allergy 2016 - Review. PMID 27196817
Polyethylene glycols (PEGs) or macrogols are polyether compounds widely used in medical and household products. Although generally considered biologically inert, cases of mild to life-threatening immediate-type PEG hypersensitivity are reported with increasing frequency. ...
Polyethylene glycols (PEGs) or macrogols are polyether compounds widely used in medical and household products. Although gener
Safety assessment on polyethylene glycols (PEGs) and their derivatives as used in cosmetic products.
Fruijtier-Pölloth C. Toxicology 2005 - Review. PMID 16011869
This assessment focusses on polyethylene glycols (PEGs) and on anionic or nonionic PEG derivatives, which are currently used in cosmetics in Europe. ...
This assessment focusses on polyethylene glycols (PEGs) and on anionic or nonionic PEG derivatives, which are currently used i …
PEG-asparaginase induced severe hypertriglyceridemia
Galindo RJ, et al. Arch Endocrinol Metab 2016 - Review. PMID 26331232 Free article.
HTG is a rare but clinically important adverse effect of PEG. Underlying obesity and/or diabetes may represent risk factors. ...
HTG is a rare but clinically important adverse effect of PEG. Underlying obesity and/or diabetes may represent risk factors. ...
Pegylated-asparaginase during induction therapy for adult acute lymphoblastic leukaemia: toxicity data from the UKALL14 trial
Patel B, et al. Leukemia 2017 - Clinical Trial. PMID 27480385 Free PMC article.
Of the 74 patients who did not die, 37 (50.0%) experienced at least one grade 3/4 PEG-ASP-related adverse event, most commonly hepatotoxicity (36.5%, n=27). ...
Of the 74 patients who did not die, 37 (50.0%) experienced at least one grade 3/4 PEG-ASP-related adverse event, most commonly hepato …
PEGylated Biopharmaceuticals: Current Experience and Considerations for Nonclinical Development
Ivens IA, et al. Toxicol Pathol 2015 - Review. PMID 26239651
Adverse effects seen with those in toxicology studies are mostly related to the active part of the drug molecule and not to polyethylene glycol (PEG). ...No other effects attributed to PEG alone have been reported. Importantly, vacuolation, which occurs mainly in phagocytes, has not been linked with changes in organ function in these toxicology studies. ...
Adverse effects seen with those in toxicology studies are mostly related to the active part of the drug molecule and not to
Polyethylene glycol: its adverse gastric effects in rats.
Cho CH, et al. J Pharm Pharmacol 1992. PMID 1359078
The effects of polyethylene glycol (PEG) on gastric function and on lesion formation, evoked by topical applications of absolute ethanol to an ex-vivo stomach chamber preparation have been examined. Parenteral injection (i.p. or s.c.) of PEG with different molecular weights (PEG 300, 400 or 4000), dose-dependently reduced the gastric mucosal blood flow and volume of gastric secretion; these effects were greater in rats given PEG by the i.p. route, which also lowered acid output. ...
The effects of polyethylene glycol (PEG) on gastric function and on lesion formation, evoked by topical applications of absolu …
Safety Assessment of PEGs Cocamine and Related Ingredients as Used in Cosmetics
Boyer I, et al. Int J Toxicol 2018. PMID 30235961
The Cosmetic Ingredient Review Expert Panel assessed the safety of 47 polyethylene glycols (PEGs) cocamine and related ingredients, which are reported to function mostly as surfactants and antistatic agents. ...
The Cosmetic Ingredient Review Expert Panel assessed the safety of 47 polyethylene glycols (PEGs) cocamine and related ingredi …
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