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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1972 1
1973 2
1974 2
1975 12
1976 4
1977 8
1978 10
1979 15
1980 18
1981 20
1982 25
1983 23
1984 31
1985 26
1986 44
1987 35
1988 46
1989 37
1990 73
1991 59
1992 83
1993 70
1994 74
1995 74
1996 77
1997 79
1998 75
1999 91
2000 93
2001 111
2002 128
2003 163
2004 194
2005 251
2006 297
2007 406
2008 429
2009 512
2010 623
2011 691
2012 701
2013 687
2014 706
2015 624
2016 533
2017 477
2018 395
2019 189
2020 4
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8,292 results
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Page 1
Osmotic and stimulant laxatives for the management of childhood constipation
Gordon M, et al. Cochrane Database Syst Rev 2016 - Review. PMID 27531591 Free PMC article.
Meta-analysis of two studies (101 patients) comparing polyethylene glycol (PEG) with placebo showed a significantly increased number of stools per week with PEG (MD 2.61 stools per week, 95% CI 1.15 to 4.08). ...Further research is needed to investigate the long term use of PEG for childhood constipation, as well as the role of liquid paraffin. ...
Meta-analysis of two studies (101 patients) comparing polyethylene glycol (PEG) with placebo showed a significantly increased number …
Polyethylene Glycol 3350 With Electrolytes Versus Polyethylene Glycol 4000 for Constipation: A Randomized, Controlled Trial.
Bekkali NLH, et al. J Pediatr Gastroenterol Nutr 2018 - Clinical Trial. PMID 28906317 Free PMC article.
OBJECTIVE: The long-term efficacy and safety of polyethylene glycol (PEG) in constipated children are unknown, and a head-to-head comparison of the different PEG formulations is lacking. ...Daily sachet use was: 0 to 2 years: 0.4 to 2.3 and 0.9 to 2.1; 2 to 4 years: 0.1 to 3.5 and 1.2 to 3.2; 4 to 8 years: 1.1 to 2.8 and 0.7 to 3.8; 8 to 16 years 0.6 to 3.7 and 1.0 to 3.7, in PEG3350 + E and PEG4000, respectively. ...
OBJECTIVE: The long-term efficacy and safety of polyethylene glycol (PEG) in constipated children are unknown, and a head-to-head com …
Management of Childhood Functional Constipation: Consensus Practice Guidelines of Indian Society of Pediatric Gastroenterology, Hepatology and Nutrition and Pediatric Gastroenterology Chapter of Indian Academy of Pediatrics
Yachha SK, et al. Indian Pediatr 2018. PMID 29941697 Free article.
Those with impaction and/or retentive incontinence should be disimpacted with polyethylene glycol (hospital or home-based). Osmotic laxatives (polyethylene glycol more than 1 year of age and lactulose/lactitol less than 1 year of age) are the first line of maintenance therapy. ...
Those with impaction and/or retentive incontinence should be disimpacted with polyethylene glycol (hospital or home-based). Osmotic l …
Role of Polyethylene Glycol in the Treatment of Functional Constipation in Children.
Koppen IJN, et al. J Pediatr Gastroenterol Nutr 2017 - Review. PMID 28777126
According to international guidelines, polyethylene glycol (PEG) is the laxative of first choice in the treatment of functional constipation in children, both for disimpaction and for maintenance treatment. ...Overall the use of PEG in children has been reported to be safe, although in patients predisposed to water and electrolyte imbalances monitoring of serum electrolytes should be considered....
According to international guidelines, polyethylene glycol (PEG) is the laxative of first choice in the treatment of functional const …
Surfactants and their role in wound cleansing and biofilm management
Percival SL, et al. J Wound Care 2017 - Review. PMID 29131752
In complex or chronic wounds that are complicated by biofilms, persistent inflammation or the production of non-viable tissue and slough, the use of surfactants has been shown to aid in the removal of these barriers to wound healing. The use of concentrated surfactant(poloxamer) based wound dressings represent an important component of wound management. Consequently, this article will discuss the effect of clinically used surfactants, with specific focus on a concentrated poloxamer for use against wound biofilm....
In complex or chronic wounds that are complicated by biofilms, persistent inflammation or the production of non-viable tissue and slough, th …
An Evidence-Based Review of Off-Label Uses of Polidocanol
Ebrahimi SRS, et al. Curr Clin Pharmacol 2017 - Review. PMID 29473522
This article attempts to provide physicians with the latest information concerning successful and unsuccessful use of polidocanol as an alternative treatment for esophageal and gastric varices, tendinopathy and epicondylitis, vascular malformations, varicocele, hydrocele and spermatocele, aneurysmal bone cysts, itching, management of gastrointestinal bleeding, simple renal cysts, reducing the incidence and severity of radio-induced dermatitis and hemorrhoids. ...
This article attempts to provide physicians with the latest information concerning successful and unsuccessful use of polidocanol as …
Certolizumab pegol for the treatment of psoriasis
Campanati A, et al. Expert Opin Biol Ther 2017 - Review. PMID 28165828
TNF-alpha inhibitors have shown long-term efficacy and safety/tolerability in psoriasis, and preliminary data support the use of certolizumab pegol (CZP) as well. ...CZP seems to be a promising therapeutic option for psoriasis patients, although further evidence supporting the continuing clinical program for development of CZP in psoriasis is needed....
TNF-alpha inhibitors have shown long-term efficacy and safety/tolerability in psoriasis, and preliminary data support the use of cert …
Comparison of the effectiveness of polyethylene glycol with and without electrolytes in constipation: a systematic review and network meta-analysis.
Katelaris P, et al. BMC Gastroenterol 2016 - Review. PMID 27029340 Free PMC article.
METHODS: A systematic review was conducted to identify randomised controlled clinical trials that assessed the use of polyethylene glycol in functional constipation. ...The addition of electrolytes to polyethylene glycol does not appear to offer any clinical benefits over polyethylene glycol alone in the management of constipation....
METHODS: A systematic review was conducted to identify randomised controlled clinical trials that assessed the use of polyethylene
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