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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 7
1993 16
1994 26
1995 40
1996 52
1997 46
1998 45
1999 61
2000 92
2001 96
2002 128
2003 136
2004 172
2005 188
2006 284
2007 353
2008 341
2009 342
2010 335
2011 319
2012 357
2013 387
2014 491
2015 540
2016 522
2017 511
2018 466
2019 164
2020 2
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5,438 results
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Page 1
Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications.
Goldstein RZ and Volkow ND. Nat Rev Neurosci 2011 - Review. PMID 22011681 Free PMC article.
However, imaging studies in addictive behaviours have identified a key involvement of the prefrontal cortex (PFC) both through its regulation of limbic reward regions and its involvement in higher-order executive function (for example, self-control, salience attribution and awareness). ...
However, imaging studies in addictive behaviours have identified a key involvement of the prefrontal cortex (PFC) both through …
Impact of anxiety on prefrontal cortex encoding of cognitive flexibility.
Park J and Moghaddam B. Neuroscience 2017 - Review. PMID 27316551 Free PMC article.
The brain region most critically involved in behavioral flexibility is the prefrontal cortex (PFC), but little is known about how anxiety impacts PFC encoding of internal and external events that are critical for flexible behavior. ...
The brain region most critically involved in behavioral flexibility is the prefrontal cortex (PFC), but little is known about …
Human lesion studies of ventromedial prefrontal cortex.
Schneider B and Koenigs M. Neuropsychologia 2017 - Review. PMID 28966138
Studies of neurological patients with focal lesions involving ventromedial prefrontal cortex (vmPFC) have demonstrated a critical role for this brain area in various aspects of cognition, emotion, and behavior. ...
Studies of neurological patients with focal lesions involving ventromedial prefrontal cortex (vmPFC) have demonstrated a criti …
Medial prefrontal cortex supports perceptual memory.
Schwiedrzik CM, et al. Curr Biol 2018. PMID 30253147 Free article.
The role of higher-order areas, especially prefrontal cortex (PFC), in perceptual memory is less explored. Because PFC exhibits long neural time constants, invariance properties, and large receptive fields which may stabilize perception against time-varying inputs, it seems particularly suited to implement perceptual memory [4]. ...
The role of higher-order areas, especially prefrontal cortex (PFC), in perceptual memory is less explored. Because PFC exhibit …
Stress weakens prefrontal networks: molecular insults to higher cognition.
Arnsten AF. Nat Neurosci 2015 - Review. PMID 26404712 Free PMC article.
A variety of cognitive disorders are worsened by stress exposure and involve dysfunction of the newly evolved prefrontal cortex (PFC). ...
A variety of cognitive disorders are worsened by stress exposure and involve dysfunction of the newly evolved prefrontal cortex
The brain on stress: vulnerability and plasticity of the prefrontal cortex over the life course.
McEwen BS and Morrison JH. Neuron 2013 - Review. PMID 23849196 Free PMC article.
The prefrontal cortex (PFC) is involved in working memory and self-regulatory and goal-directed behaviors and displays remarkable structural and functional plasticity over the life course. ...
The prefrontal cortex (PFC) is involved in working memory and self-regulatory and goal-directed behaviors and displays remarka …
Emerging role for the medial prefrontal cortex in alcohol-seeking behaviors.
Klenowski PM. Addict Behav 2018 - Review. PMID 28992574
The medial prefrontal cortex (mPFC) plays an important role in high-order executive processes and sends highly organized projections to sub-cortical regions controlling mood, motivation and impulsivity. ...
The medial prefrontal cortex (mPFC) plays an important role in high-order executive processes and sends highly organized proje …
Impaired neuroplasticity in the prefrontal cortex in depression indexed through paired associative stimulation.
Noda Y, et al. Depress Anxiety 2018. PMID 29637656
We have previously established methods to assess neuroplasticity from the dorsolateral prefrontal cortex (DLPFC) using a paired associative stimulation (PAS) paradigm, which pairs a preceding peripheral nerve stimulation with subsequent transcranial magnetic stimulation (TMS) combined with electroencephalography (EEG). ...
We have previously established methods to assess neuroplasticity from the dorsolateral prefrontal cortex (DLPFC) using a paire …
Cortico-limbic pain mechanisms
Thompson JM and Neugebauer V. Neurosci Lett 2019 - Review. PMID 30503916 Free PMC article.
Underlying mechanisms are still not well understood but an important role for interactions between prefrontal cortical areas and subcortical limbic structures has emerged. Evidence from preclinical studies in the rodent brain suggests that neuroplastic changes in prefrontal (anterior cingulate, prelimbic and infralimbic) cortical and subcortical (amygdala and nucleus accumbens) brain areas and their interactions (corticolimbic circuitry) contribute to the complexity and persistence of pain and may be predetermining factors as has been proposed in recent human neuroimaging studies....
Underlying mechanisms are still not well understood but an important role for interactions between prefrontal cortical areas and subc …
Ventromedial prefrontal cortex activity and pathological worry in generalised anxiety disorder.
Via E, et al. Br J Psychiatry 2018. PMID 29739481
The ventromedial prefrontal cortex (vmPFC) is involved in the regulation of such processes, but the link between vmPFC emotional responses and pathological v. adaptive worry has not yet been examined.AimsTo study the association between worry and vmPFC activity evoked by the processing of learned safety and threat signals. ...
The ventromedial prefrontal cortex (vmPFC) is involved in the regulation of such processes, but the link between vmPFC emotion …
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