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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1969 1
1971 1
1972 1
1999 1
2005 3
2006 1
2008 1
2009 2
2010 1
2011 2
2012 3
2013 2
2014 2
2015 2
2018 1
2020 0
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21 results
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Page 1
Add-On Pregnenolone with L-Theanine to Antipsychotic Therapy Relieves Negative and Anxiety Symptoms of Schizophrenia: An 8-Week, Randomized, Double-Blind, Placebo-Controlled Trial.
Kardashev A, Ratner Y, Ritsner MS. Kardashev A, et al. Clin Schizophr Relat Psychoses. 2018 Spring;12(1):31-41. doi: 10.3371/CSRP.KARA.070415. Epub 2015 Jul 28. Clin Schizophr Relat Psychoses. 2018. PMID: 26218236 Clinical Trial.
Pregnenolone can protect the brain from cannabis intoxication.
Vallée M, Vitiello S, Bellocchio L, Hébert-Chatelain E, Monlezun S, Martin-Garcia E, Kasanetz F, Baillie GL, Panin F, Cathala A, Roullot-Lacarrière V, Fabre S, Hurst DP, Lynch DL, Shore DM, Deroche-Gamonet V, Spampinato U, Revest JM, Maldonado R, Reggio PH, Ross RA, Marsicano G, Piazza PV. Vallée M, et al. Science. 2014 Jan 3;343(6166):94-8. doi: 10.1126/science.1243985. Science. 2014. PMID: 24385629 Free PMC article.
Pregnenolone and dehydroepiandrosterone as an adjunctive treatment in schizophrenia and schizoaffective disorder: an 8-week, double-blind, randomized, controlled, 2-center, parallel-group trial.
Ritsner MS, Gibel A, Shleifer T, Boguslavsky I, Zayed A, Maayan R, Weizman A, Lerner V. Ritsner MS, et al. J Clin Psychiatry. 2010 Oct;71(10):1351-62. doi: 10.4088/JCP.09m05031yel. Epub 2010 Jun 15. J Clin Psychiatry. 2010. PMID: 20584515 Clinical Trial.
Pregnenolone co-treatment partially restores steroidogenesis, but does not prevent growth inhibition and increased atresia in mouse ovarian antral follicles treated with mono-hydroxy methoxychlor.
Craig ZR, Hannon PR, Flaws JA. Craig ZR, et al. Toxicol Appl Pharmacol. 2013 Nov 1;272(3):780-6. doi: 10.1016/j.taap.2013.08.002. Epub 2013 Aug 13. Toxicol Appl Pharmacol. 2013. PMID: 23948739 Free PMC article.
Proof-of-concept trial with the neurosteroid pregnenolone targeting cognitive and negative symptoms in schizophrenia.
Marx CE, Keefe RS, Buchanan RW, Hamer RM, Kilts JD, Bradford DW, Strauss JL, Naylor JC, Payne VM, Lieberman JA, Savitz AJ, Leimone LA, Dunn L, Porcu P, Morrow AL, Shampine LJ. Marx CE, et al. Neuropsychopharmacology. 2009 Jul;34(8):1885-903. doi: 10.1038/npp.2009.26. Epub 2009 Apr 1. Neuropsychopharmacology. 2009. PMID: 19339966 Free PMC article. Clinical Trial.
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